| Full name: microtubule associated monooxygenase, calponin and LIM domain containing 1 | Alias Symbol: MICAL|FLJ11937|DKFZp434B1517|FLJ21739 | ||
| Type: protein-coding gene | Cytoband: 6q21 | ||
| Entrez ID: 64780 | HGNC ID: HGNC:20619 | Ensembl Gene: ENSG00000135596 | OMIM ID: 607129 |
| Drug and gene relationship at DGIdb | |||
Expression of MICAL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MICAL1 | 64780 | 218376_s_at | -0.1300 | 0.8690 | |
| GSE20347 | MICAL1 | 64780 | 218376_s_at | 0.1212 | 0.6273 | |
| GSE23400 | MICAL1 | 64780 | 218376_s_at | -0.0073 | 0.9449 | |
| GSE26886 | MICAL1 | 64780 | 218376_s_at | 1.0112 | 0.0002 | |
| GSE29001 | MICAL1 | 64780 | 218376_s_at | 0.0542 | 0.9076 | |
| GSE38129 | MICAL1 | 64780 | 218376_s_at | -0.0032 | 0.9893 | |
| GSE45670 | MICAL1 | 64780 | 218376_s_at | -0.2129 | 0.3330 | |
| GSE53622 | MICAL1 | 64780 | 131399 | 0.1629 | 0.1192 | |
| GSE53624 | MICAL1 | 64780 | 47929 | -0.1884 | 0.0150 | |
| GSE63941 | MICAL1 | 64780 | 218376_s_at | -2.3889 | 0.0003 | |
| GSE77861 | MICAL1 | 64780 | 218376_s_at | -0.0271 | 0.9219 | |
| GSE97050 | MICAL1 | 64780 | A_33_P3324884 | 0.5491 | 0.1890 | |
| SRP007169 | MICAL1 | 64780 | RNAseq | -0.7260 | 0.2026 | |
| SRP008496 | MICAL1 | 64780 | RNAseq | -0.6704 | 0.0634 | |
| SRP064894 | MICAL1 | 64780 | RNAseq | 0.3207 | 0.0734 | |
| SRP133303 | MICAL1 | 64780 | RNAseq | -0.4291 | 0.0036 | |
| SRP193095 | MICAL1 | 64780 | RNAseq | 0.0605 | 0.8146 | |
| SRP219564 | MICAL1 | 64780 | RNAseq | 0.0105 | 0.9684 | |
| TCGA | MICAL1 | 64780 | RNAseq | -0.2421 | 0.0020 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by MICAL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MICAL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MICAL1 | 64780 | 3 | 3 | 24 | |
| GSE20123 | MICAL1 | 64780 | 3 | 2 | 25 | |
| GSE43470 | MICAL1 | 64780 | 3 | 1 | 39 | |
| GSE46452 | MICAL1 | 64780 | 2 | 11 | 46 | |
| GSE47630 | MICAL1 | 64780 | 9 | 4 | 27 | |
| GSE54993 | MICAL1 | 64780 | 3 | 2 | 65 | |
| GSE54994 | MICAL1 | 64780 | 8 | 8 | 37 | |
| GSE60625 | MICAL1 | 64780 | 0 | 2 | 9 | |
| GSE74703 | MICAL1 | 64780 | 2 | 1 | 33 | |
| GSE74704 | MICAL1 | 64780 | 1 | 0 | 19 | |
| TCGA | MICAL1 | 64780 | 6 | 24 | 66 |
Total number of gains: 40; Total number of losses: 58; Total Number of normals: 390.
Somatic mutations of MICAL1:
Generating mutation plots.
Highly correlated genes for MICAL1:
Showing top 20/342 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MICAL1 | MMP3 | 0.843234 | 3 | 0 | 3 |
| MICAL1 | KDELR3 | 0.829598 | 3 | 0 | 3 |
| MICAL1 | VCAN | 0.788867 | 3 | 0 | 3 |
| MICAL1 | SEC24D | 0.787079 | 3 | 0 | 3 |
| MICAL1 | CLEC11A | 0.775689 | 4 | 0 | 4 |
| MICAL1 | FAP | 0.770699 | 3 | 0 | 3 |
| MICAL1 | THY1 | 0.765482 | 3 | 0 | 3 |
| MICAL1 | COL8A1 | 0.759658 | 3 | 0 | 3 |
| MICAL1 | TMEM158 | 0.759066 | 3 | 0 | 3 |
| MICAL1 | ZNF469 | 0.75451 | 3 | 0 | 3 |
| MICAL1 | COL4A1 | 0.746845 | 3 | 0 | 3 |
| MICAL1 | COL1A2 | 0.745369 | 3 | 0 | 3 |
| MICAL1 | DCBLD1 | 0.741733 | 3 | 0 | 3 |
| MICAL1 | DPY19L1 | 0.740971 | 3 | 0 | 3 |
| MICAL1 | COL1A1 | 0.736546 | 3 | 0 | 3 |
| MICAL1 | RAB7B | 0.734241 | 3 | 0 | 3 |
| MICAL1 | SERPINE1 | 0.734088 | 3 | 0 | 3 |
| MICAL1 | PODNL1 | 0.730831 | 3 | 0 | 3 |
| MICAL1 | C12orf75 | 0.730079 | 3 | 0 | 3 |
| MICAL1 | FST | 0.728517 | 3 | 0 | 3 |
For details and further investigation, click here
