| Full name: orthopedia homeobox | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 5q14.1 | ||
| Entrez ID: 23440 | HGNC ID: HGNC:8518 | Ensembl Gene: ENSG00000171540 | OMIM ID: 604529 |
| Drug and gene relationship at DGIdb | |||
Expression of OTP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OTP | 23440 | 231488_at | -0.1823 | 0.4224 | |
| GSE26886 | OTP | 23440 | 231488_at | -0.1065 | 0.3178 | |
| GSE45670 | OTP | 23440 | 231488_at | -0.1203 | 0.1609 | |
| GSE53622 | OTP | 23440 | 19217 | 0.0226 | 0.8313 | |
| GSE53624 | OTP | 23440 | 19217 | -0.1883 | 0.1721 | |
| GSE63941 | OTP | 23440 | 231488_at | 0.0379 | 0.8089 | |
| GSE77861 | OTP | 23440 | 231488_at | -0.1413 | 0.2522 | |
| TCGA | OTP | 23440 | RNAseq | 3.1177 | 0.0042 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by OTP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OTP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OTP | 23440 | 1 | 13 | 16 | |
| GSE20123 | OTP | 23440 | 1 | 13 | 16 | |
| GSE43470 | OTP | 23440 | 1 | 13 | 29 | |
| GSE46452 | OTP | 23440 | 0 | 28 | 31 | |
| GSE47630 | OTP | 23440 | 1 | 19 | 20 | |
| GSE54993 | OTP | 23440 | 8 | 1 | 61 | |
| GSE54994 | OTP | 23440 | 1 | 19 | 33 | |
| GSE60625 | OTP | 23440 | 0 | 0 | 11 | |
| GSE74703 | OTP | 23440 | 1 | 9 | 26 | |
| GSE74704 | OTP | 23440 | 1 | 6 | 13 | |
| TCGA | OTP | 23440 | 5 | 49 | 42 |
Total number of gains: 20; Total number of losses: 170; Total Number of normals: 298.
Somatic mutations of OTP:
Generating mutation plots.
Highly correlated genes for OTP:
Showing all 20 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OTP | PEX14 | 0.687987 | 3 | 0 | 3 |
| OTP | RTN4RL2 | 0.61651 | 3 | 0 | 3 |
| OTP | DUOXA2 | 0.610792 | 3 | 0 | 3 |
| OTP | OVGP1 | 0.609776 | 3 | 0 | 3 |
| OTP | LIPE-AS1 | 0.604154 | 3 | 0 | 3 |
| OTP | NOBOX | 0.598884 | 4 | 0 | 3 |
| OTP | HBM | 0.597973 | 3 | 0 | 3 |
| OTP | TESPA1 | 0.581163 | 4 | 0 | 3 |
| OTP | OR2C1 | 0.573212 | 5 | 0 | 3 |
| OTP | A1CF | 0.565636 | 5 | 0 | 4 |
| OTP | TTTY11 | 0.553629 | 3 | 0 | 3 |
| OTP | EP300-AS1 | 0.546522 | 4 | 0 | 3 |
| OTP | KCNK9 | 0.536025 | 3 | 0 | 3 |
| OTP | DRD3 | 0.532228 | 4 | 0 | 3 |
| OTP | ZGLP1 | 0.529691 | 4 | 0 | 3 |
| OTP | LINC01136 | 0.52232 | 4 | 0 | 3 |
| OTP | LACRT | 0.518769 | 4 | 0 | 3 |
| OTP | C22orf15 | 0.518131 | 4 | 0 | 3 |
| OTP | CHRND | 0.511822 | 5 | 0 | 3 |
| OTP | PRG3 | 0.50692 | 4 | 0 | 3 |
For details and further investigation, click here
