| Full name: acid phosphatase 6, lysophosphatidic | Alias Symbol: LPAP|ACPL1 | ||
| Type: protein-coding gene | Cytoband: 1q21.2 | ||
| Entrez ID: 51205 | HGNC ID: HGNC:29609 | Ensembl Gene: ENSG00000162836 | OMIM ID: 611471 |
| Drug and gene relationship at DGIdb | |||
Expression of ACP6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ACP6 | 51205 | 218795_at | -0.1015 | 0.7869 | |
| GSE20347 | ACP6 | 51205 | 218795_at | -0.2067 | 0.2538 | |
| GSE23400 | ACP6 | 51205 | 218795_at | -0.2697 | 0.0006 | |
| GSE26886 | ACP6 | 51205 | 218795_at | 0.0827 | 0.8331 | |
| GSE29001 | ACP6 | 51205 | 218795_at | -0.3172 | 0.2631 | |
| GSE38129 | ACP6 | 51205 | 218795_at | -0.2396 | 0.1226 | |
| GSE45670 | ACP6 | 51205 | 218795_at | -0.1515 | 0.6215 | |
| GSE53622 | ACP6 | 51205 | 31785 | -0.2898 | 0.0211 | |
| GSE53624 | ACP6 | 51205 | 31785 | -0.4815 | 0.0000 | |
| GSE63941 | ACP6 | 51205 | 218795_at | 0.9278 | 0.2578 | |
| GSE77861 | ACP6 | 51205 | 218795_at | -0.3065 | 0.2600 | |
| GSE97050 | ACP6 | 51205 | A_23_P160240 | -0.3225 | 0.4073 | |
| SRP007169 | ACP6 | 51205 | RNAseq | -0.9577 | 0.0682 | |
| SRP008496 | ACP6 | 51205 | RNAseq | -0.0827 | 0.8546 | |
| SRP064894 | ACP6 | 51205 | RNAseq | -0.2212 | 0.3173 | |
| SRP133303 | ACP6 | 51205 | RNAseq | -0.2645 | 0.2915 | |
| SRP159526 | ACP6 | 51205 | RNAseq | 0.2166 | 0.4739 | |
| SRP193095 | ACP6 | 51205 | RNAseq | -0.2916 | 0.1096 | |
| SRP219564 | ACP6 | 51205 | RNAseq | -0.0520 | 0.8915 | |
| TCGA | ACP6 | 51205 | RNAseq | -0.3437 | 0.0051 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ACP6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ACP6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ACP6 | 51205 | 12 | 0 | 18 | |
| GSE20123 | ACP6 | 51205 | 12 | 0 | 18 | |
| GSE43470 | ACP6 | 51205 | 5 | 1 | 37 | |
| GSE46452 | ACP6 | 51205 | 2 | 1 | 56 | |
| GSE47630 | ACP6 | 51205 | 12 | 2 | 26 | |
| GSE54993 | ACP6 | 51205 | 0 | 2 | 68 | |
| GSE54994 | ACP6 | 51205 | 15 | 0 | 38 | |
| GSE60625 | ACP6 | 51205 | 0 | 0 | 11 | |
| GSE74703 | ACP6 | 51205 | 5 | 1 | 30 | |
| GSE74704 | ACP6 | 51205 | 6 | 0 | 14 | |
| TCGA | ACP6 | 51205 | 33 | 15 | 48 |
Total number of gains: 102; Total number of losses: 22; Total Number of normals: 364.
Somatic mutations of ACP6:
Generating mutation plots.
Highly correlated genes for ACP6:
Showing top 20/282 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ACP6 | SRRM1 | 0.802012 | 3 | 0 | 3 |
| ACP6 | ZNF317 | 0.792845 | 3 | 0 | 3 |
| ACP6 | BIVM | 0.788008 | 3 | 0 | 3 |
| ACP6 | ENOSF1 | 0.77812 | 3 | 0 | 3 |
| ACP6 | FAM13A | 0.774652 | 3 | 0 | 3 |
| ACP6 | RERG | 0.746693 | 3 | 0 | 3 |
| ACP6 | OTUD7B | 0.7429 | 3 | 0 | 3 |
| ACP6 | FBXL3 | 0.739389 | 3 | 0 | 3 |
| ACP6 | ADCK1 | 0.73737 | 3 | 0 | 3 |
| ACP6 | NNT | 0.735083 | 3 | 0 | 3 |
| ACP6 | MRPL20 | 0.733917 | 3 | 0 | 3 |
| ACP6 | RCOR3 | 0.728996 | 4 | 0 | 3 |
| ACP6 | PITHD1 | 0.728895 | 3 | 0 | 3 |
| ACP6 | RFX5 | 0.728121 | 3 | 0 | 3 |
| ACP6 | SLC44A4 | 0.725021 | 3 | 0 | 3 |
| ACP6 | COX15 | 0.724303 | 3 | 0 | 3 |
| ACP6 | CYP2U1 | 0.723222 | 3 | 0 | 3 |
| ACP6 | MYL6B | 0.722161 | 3 | 0 | 3 |
| ACP6 | ZNF564 | 0.719724 | 4 | 0 | 3 |
| ACP6 | HACL1 | 0.715679 | 4 | 0 | 3 |
For details and further investigation, click here
