| Full name: poly(A) binding protein cytoplasmic 3 | Alias Symbol: PABP3|tPABP | ||
| Type: protein-coding gene | Cytoband: 13q12.13 | ||
| Entrez ID: 5042 | HGNC ID: HGNC:8556 | Ensembl Gene: ENSG00000151846 | OMIM ID: 604680 |
| Drug and gene relationship at DGIdb | |||
Expression of PABPC3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PABPC3 | 5042 | 208113_x_at | 0.1513 | 0.7075 | |
| GSE20347 | PABPC3 | 5042 | 208113_x_at | -0.1317 | 0.2766 | |
| GSE23400 | PABPC3 | 5042 | 208113_x_at | -0.3091 | 0.0003 | |
| GSE26886 | PABPC3 | 5042 | 208113_x_at | -0.2934 | 0.1059 | |
| GSE29001 | PABPC3 | 5042 | 208113_x_at | -0.2166 | 0.1616 | |
| GSE38129 | PABPC3 | 5042 | 208113_x_at | -0.0542 | 0.6385 | |
| GSE45670 | PABPC3 | 5042 | 208113_x_at | -0.0552 | 0.5270 | |
| GSE53622 | PABPC3 | 5042 | 22215 | -0.4774 | 0.0000 | |
| GSE53624 | PABPC3 | 5042 | 22215 | -0.4790 | 0.0000 | |
| GSE63941 | PABPC3 | 5042 | 208113_x_at | -0.0717 | 0.8303 | |
| GSE77861 | PABPC3 | 5042 | 208113_x_at | -0.3508 | 0.0066 | |
| GSE97050 | PABPC3 | 5042 | A_23_P48307 | -0.1592 | 0.6191 | |
| TCGA | PABPC3 | 5042 | RNAseq | 0.1494 | 0.0318 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PABPC3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PABPC3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PABPC3 | 5042 | 1 | 12 | 17 | |
| GSE20123 | PABPC3 | 5042 | 1 | 11 | 18 | |
| GSE43470 | PABPC3 | 5042 | 2 | 12 | 29 | |
| GSE46452 | PABPC3 | 5042 | 0 | 33 | 26 | |
| GSE47630 | PABPC3 | 5042 | 3 | 26 | 11 | |
| GSE54993 | PABPC3 | 5042 | 11 | 2 | 57 | |
| GSE54994 | PABPC3 | 5042 | 1 | 13 | 39 | |
| GSE60625 | PABPC3 | 5042 | 0 | 3 | 8 | |
| GSE74703 | PABPC3 | 5042 | 2 | 9 | 25 | |
| GSE74704 | PABPC3 | 5042 | 0 | 9 | 11 | |
| TCGA | PABPC3 | 5042 | 5 | 46 | 45 |
Total number of gains: 26; Total number of losses: 176; Total Number of normals: 286.
Somatic mutations of PABPC3:
Generating mutation plots.
Highly correlated genes for PABPC3:
Showing top 20/397 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PABPC3 | PABPC1 | 0.868324 | 13 | 0 | 13 |
| PABPC3 | GPT2 | 0.695012 | 4 | 0 | 4 |
| PABPC3 | SCRIB | 0.670785 | 10 | 0 | 9 |
| PABPC3 | MOV10 | 0.666288 | 3 | 0 | 3 |
| PABPC3 | CPNE3 | 0.65944 | 11 | 0 | 11 |
| PABPC3 | VSIG10L | 0.655802 | 5 | 0 | 4 |
| PABPC3 | SERPINB5 | 0.632129 | 3 | 0 | 3 |
| PABPC3 | DENND1B | 0.631476 | 4 | 0 | 4 |
| PABPC3 | FAM83H | 0.631213 | 3 | 0 | 3 |
| PABPC3 | TPRN | 0.623544 | 5 | 0 | 5 |
| PABPC3 | BRWD3 | 0.62202 | 3 | 0 | 3 |
| PABPC3 | ZBTB42 | 0.618103 | 3 | 0 | 3 |
| PABPC3 | ESRP1 | 0.618032 | 11 | 0 | 9 |
| PABPC3 | HMGN1 | 0.615863 | 4 | 0 | 3 |
| PABPC3 | PERP | 0.614016 | 7 | 0 | 4 |
| PABPC3 | DENND2C | 0.613546 | 5 | 0 | 4 |
| PABPC3 | DEGS2 | 0.613506 | 5 | 0 | 4 |
| PABPC3 | SEMA3F | 0.61324 | 8 | 0 | 6 |
| PABPC3 | CYSRT1 | 0.612578 | 4 | 0 | 3 |
| PABPC3 | CNFN | 0.60939 | 5 | 0 | 4 |
For details and further investigation, click here
