| Full name: epithelial splicing regulatory protein 1 | Alias Symbol: FLJ20171 | ||
| Type: protein-coding gene | Cytoband: 8q22.1 | ||
| Entrez ID: 54845 | HGNC ID: HGNC:25966 | Ensembl Gene: ENSG00000104413 | OMIM ID: 612959 |
| Drug and gene relationship at DGIdb | |||
Expression of ESRP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ESRP1 | 54845 | 225846_at | 0.2672 | 0.7935 | |
| GSE20347 | ESRP1 | 54845 | 219121_s_at | -0.8948 | 0.0000 | |
| GSE23400 | ESRP1 | 54845 | 219121_s_at | -0.5498 | 0.0000 | |
| GSE26886 | ESRP1 | 54845 | 225846_at | -0.8247 | 0.0003 | |
| GSE29001 | ESRP1 | 54845 | 219121_s_at | -0.9055 | 0.0181 | |
| GSE38129 | ESRP1 | 54845 | 219121_s_at | -0.1622 | 0.7355 | |
| GSE45670 | ESRP1 | 54845 | 225846_at | -0.0107 | 0.9577 | |
| GSE53622 | ESRP1 | 54845 | 121906 | -0.0663 | 0.8327 | |
| GSE53624 | ESRP1 | 54845 | 121906 | -0.7542 | 0.0000 | |
| GSE63941 | ESRP1 | 54845 | 219121_s_at | 6.3359 | 0.0001 | |
| GSE77861 | ESRP1 | 54845 | 225846_at | -0.2877 | 0.0830 | |
| GSE97050 | ESRP1 | 54845 | A_23_P259127 | 1.3670 | 0.3319 | |
| SRP007169 | ESRP1 | 54845 | RNAseq | -1.4807 | 0.0000 | |
| SRP008496 | ESRP1 | 54845 | RNAseq | -1.3169 | 0.0000 | |
| SRP064894 | ESRP1 | 54845 | RNAseq | -0.8481 | 0.0411 | |
| SRP133303 | ESRP1 | 54845 | RNAseq | -0.6096 | 0.0006 | |
| SRP159526 | ESRP1 | 54845 | RNAseq | -0.9476 | 0.0001 | |
| SRP193095 | ESRP1 | 54845 | RNAseq | -0.9214 | 0.0000 | |
| SRP219564 | ESRP1 | 54845 | RNAseq | -1.0943 | 0.3667 | |
| TCGA | ESRP1 | 54845 | RNAseq | 0.2771 | 0.0650 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by ESRP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ESRP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ESRP1 | 54845 | 16 | 0 | 14 | |
| GSE20123 | ESRP1 | 54845 | 17 | 0 | 13 | |
| GSE43470 | ESRP1 | 54845 | 21 | 1 | 21 | |
| GSE46452 | ESRP1 | 54845 | 22 | 0 | 37 | |
| GSE47630 | ESRP1 | 54845 | 24 | 0 | 16 | |
| GSE54993 | ESRP1 | 54845 | 0 | 20 | 50 | |
| GSE54994 | ESRP1 | 54845 | 34 | 1 | 18 | |
| GSE60625 | ESRP1 | 54845 | 0 | 4 | 7 | |
| GSE74703 | ESRP1 | 54845 | 18 | 1 | 17 | |
| GSE74704 | ESRP1 | 54845 | 12 | 0 | 8 | |
| TCGA | ESRP1 | 54845 | 56 | 1 | 39 |
Total number of gains: 220; Total number of losses: 28; Total Number of normals: 240.
Somatic mutations of ESRP1:
Generating mutation plots.
Highly correlated genes for ESRP1:
Showing top 20/934 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ESRP1 | FAM83H | 0.758503 | 5 | 0 | 4 |
| ESRP1 | SPINT2 | 0.747688 | 7 | 0 | 6 |
| ESRP1 | MAL2 | 0.742252 | 8 | 0 | 6 |
| ESRP1 | TFAP2A | 0.726798 | 5 | 0 | 5 |
| ESRP1 | EIF2S3 | 0.725476 | 3 | 0 | 3 |
| ESRP1 | ARAP2 | 0.724803 | 3 | 0 | 3 |
| ESRP1 | RIPK4 | 0.718541 | 7 | 0 | 6 |
| ESRP1 | CDS1 | 0.713169 | 11 | 0 | 11 |
| ESRP1 | EPHA1 | 0.711736 | 12 | 0 | 11 |
| ESRP1 | KDF1 | 0.709677 | 6 | 0 | 6 |
| ESRP1 | CXADR | 0.708954 | 7 | 0 | 5 |
| ESRP1 | SYTL1 | 0.706849 | 7 | 0 | 6 |
| ESRP1 | PERP | 0.706226 | 10 | 0 | 9 |
| ESRP1 | BAIAP2L1 | 0.705608 | 5 | 0 | 4 |
| ESRP1 | S100A11 | 0.70113 | 10 | 0 | 9 |
| ESRP1 | STAP2 | 0.700021 | 9 | 0 | 8 |
| ESRP1 | RAB25 | 0.696208 | 12 | 0 | 11 |
| ESRP1 | PKP3 | 0.69561 | 11 | 0 | 11 |
| ESRP1 | SFN | 0.695363 | 6 | 0 | 4 |
| ESRP1 | NIPAL1 | 0.694866 | 3 | 0 | 3 |
For details and further investigation, click here
