| Full name: high mobility group nucleosome binding domain 1 | Alias Symbol: FLJ27265|FLJ31471|MGC104230|MGC117425 | ||
| Type: protein-coding gene | Cytoband: 21q22.2 | ||
| Entrez ID: 3150 | HGNC ID: HGNC:4984 | Ensembl Gene: ENSG00000205581 | OMIM ID: 163920 |
| Drug and gene relationship at DGIdb | |||
Expression of HMGN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HMGN1 | 3150 | 200943_at | 0.1370 | 0.7204 | |
| GSE20347 | HMGN1 | 3150 | 200944_s_at | -0.2751 | 0.0243 | |
| GSE23400 | HMGN1 | 3150 | 200944_s_at | -0.0500 | 0.4643 | |
| GSE26886 | HMGN1 | 3150 | 200944_s_at | -0.6313 | 0.0007 | |
| GSE29001 | HMGN1 | 3150 | 200944_s_at | 0.0291 | 0.9038 | |
| GSE38129 | HMGN1 | 3150 | 200944_s_at | -0.0242 | 0.8545 | |
| GSE45670 | HMGN1 | 3150 | 200944_s_at | -0.0957 | 0.3631 | |
| GSE53622 | HMGN1 | 3150 | 5260 | 0.1267 | 0.0238 | |
| GSE53624 | HMGN1 | 3150 | 5260 | -0.0105 | 0.8621 | |
| GSE63941 | HMGN1 | 3150 | 200944_s_at | 0.0391 | 0.9055 | |
| GSE77861 | HMGN1 | 3150 | 200944_s_at | -0.5020 | 0.0062 | |
| GSE97050 | HMGN1 | 3150 | A_24_P409857 | 0.0004 | 0.9984 | |
| SRP007169 | HMGN1 | 3150 | RNAseq | -0.9615 | 0.0009 | |
| SRP008496 | HMGN1 | 3150 | RNAseq | -0.5799 | 0.0065 | |
| SRP064894 | HMGN1 | 3150 | RNAseq | 0.3037 | 0.1294 | |
| SRP133303 | HMGN1 | 3150 | RNAseq | -0.1022 | 0.2244 | |
| SRP159526 | HMGN1 | 3150 | RNAseq | -0.0102 | 0.9603 | |
| SRP193095 | HMGN1 | 3150 | RNAseq | -0.5459 | 0.0000 | |
| SRP219564 | HMGN1 | 3150 | RNAseq | 0.0006 | 0.9979 | |
| TCGA | HMGN1 | 3150 | RNAseq | 0.1068 | 0.0350 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HMGN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HMGN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HMGN1 | 3150 | 2 | 9 | 19 | |
| GSE20123 | HMGN1 | 3150 | 2 | 10 | 18 | |
| GSE43470 | HMGN1 | 3150 | 0 | 10 | 33 | |
| GSE46452 | HMGN1 | 3150 | 1 | 21 | 37 | |
| GSE47630 | HMGN1 | 3150 | 6 | 17 | 17 | |
| GSE54993 | HMGN1 | 3150 | 8 | 1 | 61 | |
| GSE54994 | HMGN1 | 3150 | 3 | 9 | 41 | |
| GSE60625 | HMGN1 | 3150 | 0 | 0 | 11 | |
| GSE74703 | HMGN1 | 3150 | 0 | 8 | 28 | |
| GSE74704 | HMGN1 | 3150 | 1 | 6 | 13 | |
| TCGA | HMGN1 | 3150 | 8 | 41 | 47 |
Total number of gains: 31; Total number of losses: 132; Total Number of normals: 325.
Somatic mutations of HMGN1:
Generating mutation plots.
Highly correlated genes for HMGN1:
Showing top 20/701 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HMGN1 | CNOT10 | 0.798348 | 3 | 0 | 3 |
| HMGN1 | ZNF844 | 0.795115 | 3 | 0 | 3 |
| HMGN1 | MTMR3 | 0.794918 | 3 | 0 | 3 |
| HMGN1 | ZNF681 | 0.791369 | 3 | 0 | 3 |
| HMGN1 | RBBP6 | 0.79023 | 3 | 0 | 3 |
| HMGN1 | ARRDC3 | 0.787849 | 3 | 0 | 3 |
| HMGN1 | MPHOSPH9 | 0.78494 | 3 | 0 | 3 |
| HMGN1 | PLEKHA7 | 0.77842 | 3 | 0 | 3 |
| HMGN1 | TADA1 | 0.774996 | 3 | 0 | 3 |
| HMGN1 | UBE2D2 | 0.765559 | 3 | 0 | 3 |
| HMGN1 | TRIM6 | 0.760566 | 3 | 0 | 3 |
| HMGN1 | ARF4 | 0.759985 | 3 | 0 | 3 |
| HMGN1 | ZNF615 | 0.756503 | 3 | 0 | 3 |
| HMGN1 | SRSF10 | 0.755461 | 3 | 0 | 3 |
| HMGN1 | LRP10 | 0.755272 | 3 | 0 | 3 |
| HMGN1 | PPP4R1 | 0.753469 | 3 | 0 | 3 |
| HMGN1 | MBNL3 | 0.752717 | 4 | 0 | 4 |
| HMGN1 | UBE2L3 | 0.751705 | 3 | 0 | 3 |
| HMGN1 | TBC1D22B | 0.744251 | 4 | 0 | 4 |
| HMGN1 | ZNF571 | 0.740881 | 3 | 0 | 3 |
For details and further investigation, click here
