| Full name: pantothenate kinase 3 | Alias Symbol: FLJ12899 | ||
| Type: protein-coding gene | Cytoband: 5q34 | ||
| Entrez ID: 79646 | HGNC ID: HGNC:19365 | Ensembl Gene: ENSG00000120137 | OMIM ID: 606161 |
| Drug and gene relationship at DGIdb | |||
Expression of PANK3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PANK3 | 79646 | 221751_at | 0.2782 | 0.4438 | |
| GSE20347 | PANK3 | 79646 | 221751_at | -0.3072 | 0.0374 | |
| GSE23400 | PANK3 | 79646 | 221751_at | -0.0443 | 0.6590 | |
| GSE26886 | PANK3 | 79646 | 221751_at | -0.4021 | 0.0624 | |
| GSE29001 | PANK3 | 79646 | 221751_at | -0.0454 | 0.8887 | |
| GSE38129 | PANK3 | 79646 | 221751_at | -0.1399 | 0.3127 | |
| GSE45670 | PANK3 | 79646 | 221751_at | -0.0418 | 0.7525 | |
| GSE53622 | PANK3 | 79646 | 42614 | -0.3933 | 0.0000 | |
| GSE53624 | PANK3 | 79646 | 89198 | -0.1974 | 0.0038 | |
| GSE63941 | PANK3 | 79646 | 221751_at | 0.2132 | 0.7365 | |
| GSE77861 | PANK3 | 79646 | 221751_at | 0.2228 | 0.4834 | |
| GSE97050 | PANK3 | 79646 | A_33_P3241646 | 0.5146 | 0.2269 | |
| SRP007169 | PANK3 | 79646 | RNAseq | -0.0397 | 0.9077 | |
| SRP008496 | PANK3 | 79646 | RNAseq | -0.3168 | 0.2057 | |
| SRP064894 | PANK3 | 79646 | RNAseq | -0.3225 | 0.2757 | |
| SRP133303 | PANK3 | 79646 | RNAseq | 0.0038 | 0.9772 | |
| SRP159526 | PANK3 | 79646 | RNAseq | 0.0864 | 0.8122 | |
| SRP193095 | PANK3 | 79646 | RNAseq | -0.4840 | 0.0002 | |
| SRP219564 | PANK3 | 79646 | RNAseq | -0.0036 | 0.9942 | |
| TCGA | PANK3 | 79646 | RNAseq | -0.0068 | 0.9225 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PANK3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PANK3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PANK3 | 79646 | 1 | 11 | 18 | |
| GSE20123 | PANK3 | 79646 | 1 | 11 | 18 | |
| GSE43470 | PANK3 | 79646 | 2 | 8 | 33 | |
| GSE46452 | PANK3 | 79646 | 0 | 27 | 32 | |
| GSE47630 | PANK3 | 79646 | 0 | 20 | 20 | |
| GSE54993 | PANK3 | 79646 | 9 | 2 | 59 | |
| GSE54994 | PANK3 | 79646 | 2 | 15 | 36 | |
| GSE60625 | PANK3 | 79646 | 1 | 0 | 10 | |
| GSE74703 | PANK3 | 79646 | 2 | 6 | 28 | |
| GSE74704 | PANK3 | 79646 | 0 | 6 | 14 | |
| TCGA | PANK3 | 79646 | 7 | 37 | 52 |
Total number of gains: 25; Total number of losses: 143; Total Number of normals: 320.
Somatic mutations of PANK3:
Generating mutation plots.
Highly correlated genes for PANK3:
Showing top 20/225 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PANK3 | CYCS | 0.791615 | 3 | 0 | 3 |
| PANK3 | PPIL4 | 0.755329 | 3 | 0 | 3 |
| PANK3 | SRFBP1 | 0.733868 | 3 | 0 | 3 |
| PANK3 | MTSS1 | 0.732046 | 3 | 0 | 3 |
| PANK3 | DENND1B | 0.731167 | 5 | 0 | 5 |
| PANK3 | CEBPG | 0.730655 | 3 | 0 | 3 |
| PANK3 | TATDN1 | 0.724428 | 3 | 0 | 3 |
| PANK3 | PNP | 0.715575 | 3 | 0 | 3 |
| PANK3 | CEP97 | 0.715075 | 4 | 0 | 4 |
| PANK3 | CDYL | 0.712059 | 4 | 0 | 3 |
| PANK3 | BRMS1L | 0.708867 | 3 | 0 | 3 |
| PANK3 | RAB22A | 0.708377 | 4 | 0 | 4 |
| PANK3 | TMEM45A | 0.700216 | 3 | 0 | 3 |
| PANK3 | SMARCA5 | 0.697479 | 3 | 0 | 3 |
| PANK3 | RBAK | 0.691692 | 3 | 0 | 3 |
| PANK3 | KRT10 | 0.691611 | 3 | 0 | 3 |
| PANK3 | LRIF1 | 0.685515 | 4 | 0 | 3 |
| PANK3 | RPF2 | 0.684577 | 3 | 0 | 3 |
| PANK3 | MBLAC2 | 0.684003 | 4 | 0 | 3 |
| PANK3 | TMCO6 | 0.680428 | 4 | 0 | 3 |
For details and further investigation, click here
