| Full name: transmembrane protein 45A | Alias Symbol: FLJ10134|DERP7 | ||
| Type: protein-coding gene | Cytoband: 3q12.2 | ||
| Entrez ID: 55076 | HGNC ID: HGNC:25480 | Ensembl Gene: ENSG00000181458 | OMIM ID: 616928 |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM45A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM45A | 55076 | 219410_at | 1.2308 | 0.3827 | |
| GSE20347 | TMEM45A | 55076 | 219410_at | 1.1581 | 0.0510 | |
| GSE23400 | TMEM45A | 55076 | 219410_at | 1.5988 | 0.0000 | |
| GSE26886 | TMEM45A | 55076 | 219410_at | 0.7767 | 0.2735 | |
| GSE29001 | TMEM45A | 55076 | 219410_at | 1.4681 | 0.0343 | |
| GSE38129 | TMEM45A | 55076 | 219410_at | 1.5317 | 0.0001 | |
| GSE45670 | TMEM45A | 55076 | 219410_at | 2.6041 | 0.0000 | |
| GSE53622 | TMEM45A | 55076 | 105964 | 1.2358 | 0.0000 | |
| GSE53624 | TMEM45A | 55076 | 105964 | 1.2463 | 0.0000 | |
| GSE63941 | TMEM45A | 55076 | 219410_at | -2.6273 | 0.0613 | |
| GSE77861 | TMEM45A | 55076 | 219410_at | 1.2068 | 0.3002 | |
| GSE97050 | TMEM45A | 55076 | A_33_P3344831 | 2.4082 | 0.0815 | |
| SRP007169 | TMEM45A | 55076 | RNAseq | -0.0279 | 0.9692 | |
| SRP008496 | TMEM45A | 55076 | RNAseq | 0.5405 | 0.5880 | |
| SRP064894 | TMEM45A | 55076 | RNAseq | 1.7785 | 0.0000 | |
| SRP133303 | TMEM45A | 55076 | RNAseq | 1.4400 | 0.0008 | |
| SRP159526 | TMEM45A | 55076 | RNAseq | 1.7688 | 0.0060 | |
| SRP193095 | TMEM45A | 55076 | RNAseq | 1.6327 | 0.0001 | |
| SRP219564 | TMEM45A | 55076 | RNAseq | 2.6822 | 0.0003 | |
| TCGA | TMEM45A | 55076 | RNAseq | 0.8266 | 0.0000 |
Upregulated datasets: 11; Downregulated datasets: 0.
Survival by TMEM45A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM45A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM45A | 55076 | 17 | 1 | 12 | |
| GSE20123 | TMEM45A | 55076 | 16 | 1 | 13 | |
| GSE43470 | TMEM45A | 55076 | 19 | 1 | 23 | |
| GSE46452 | TMEM45A | 55076 | 12 | 6 | 41 | |
| GSE47630 | TMEM45A | 55076 | 16 | 6 | 18 | |
| GSE54993 | TMEM45A | 55076 | 2 | 5 | 63 | |
| GSE54994 | TMEM45A | 55076 | 27 | 5 | 21 | |
| GSE60625 | TMEM45A | 55076 | 0 | 6 | 5 | |
| GSE74703 | TMEM45A | 55076 | 15 | 1 | 20 | |
| GSE74704 | TMEM45A | 55076 | 13 | 1 | 6 | |
| TCGA | TMEM45A | 55076 | 48 | 10 | 38 |
Total number of gains: 185; Total number of losses: 43; Total Number of normals: 260.
Somatic mutations of TMEM45A:
Generating mutation plots.
Highly correlated genes for TMEM45A:
Showing top 20/448 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM45A | RNF145 | 0.793568 | 3 | 0 | 3 |
| TMEM45A | ALPK2 | 0.708202 | 3 | 0 | 3 |
| TMEM45A | PANK3 | 0.700216 | 3 | 0 | 3 |
| TMEM45A | KRTDAP | 0.671224 | 6 | 0 | 5 |
| TMEM45A | OGDHL | 0.670963 | 3 | 0 | 3 |
| TMEM45A | CRIPT | 0.6697 | 3 | 0 | 3 |
| TMEM45A | LTF | 0.666528 | 3 | 0 | 3 |
| TMEM45A | TNFSF14 | 0.66349 | 3 | 0 | 3 |
| TMEM45A | HSD17B1 | 0.65958 | 3 | 0 | 3 |
| TMEM45A | SLC28A3 | 0.657865 | 5 | 0 | 3 |
| TMEM45A | SH3RF3 | 0.65745 | 3 | 0 | 3 |
| TMEM45A | TGFB1 | 0.652251 | 5 | 0 | 3 |
| TMEM45A | DCBLD1 | 0.648741 | 7 | 0 | 6 |
| TMEM45A | LZTS1 | 0.646749 | 3 | 0 | 3 |
| TMEM45A | S100A7A | 0.64603 | 6 | 0 | 4 |
| TMEM45A | NOSIP | 0.639465 | 4 | 0 | 4 |
| TMEM45A | BIRC3 | 0.635944 | 4 | 0 | 3 |
| TMEM45A | S100A12 | 0.635524 | 3 | 0 | 3 |
| TMEM45A | TUSC3 | 0.632611 | 8 | 0 | 6 |
| TMEM45A | TMEM70 | 0.632356 | 3 | 0 | 3 |
For details and further investigation, click here
