| Full name: keratin 10 | Alias Symbol: K10|CK10 | ||
| Type: protein-coding gene | Cytoband: 17q21.2 | ||
| Entrez ID: 3858 | HGNC ID: HGNC:6413 | Ensembl Gene: ENSG00000186395 | OMIM ID: 148080 |
| Drug and gene relationship at DGIdb | |||
Expression of KRT10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KRT10 | 3858 | 210633_x_at | 0.2864 | 0.3393 | |
| GSE20347 | KRT10 | 3858 | 210633_x_at | 0.4555 | 0.0397 | |
| GSE23400 | KRT10 | 3858 | 210633_x_at | 0.3690 | 0.0035 | |
| GSE26886 | KRT10 | 3858 | 210633_x_at | 0.3163 | 0.0882 | |
| GSE29001 | KRT10 | 3858 | 210633_x_at | 0.6990 | 0.0236 | |
| GSE38129 | KRT10 | 3858 | 213287_s_at | 0.6798 | 0.0043 | |
| GSE45670 | KRT10 | 3858 | 210633_x_at | 0.9874 | 0.0068 | |
| GSE53622 | KRT10 | 3858 | 117033 | 0.8553 | 0.0000 | |
| GSE53624 | KRT10 | 3858 | 117033 | 0.8391 | 0.0000 | |
| GSE63941 | KRT10 | 3858 | 213287_s_at | 0.2707 | 0.5663 | |
| GSE77861 | KRT10 | 3858 | 210633_x_at | 0.6320 | 0.1432 | |
| GSE97050 | KRT10 | 3858 | A_23_P49975 | 0.8974 | 0.1834 | |
| SRP007169 | KRT10 | 3858 | RNAseq | 0.1702 | 0.7650 | |
| SRP008496 | KRT10 | 3858 | RNAseq | 0.8436 | 0.4036 | |
| SRP064894 | KRT10 | 3858 | RNAseq | 0.9387 | 0.0035 | |
| SRP133303 | KRT10 | 3858 | RNAseq | 0.3462 | 0.6616 | |
| SRP159526 | KRT10 | 3858 | RNAseq | 2.5483 | 0.0010 | |
| SRP193095 | KRT10 | 3858 | RNAseq | 1.1119 | 0.0067 | |
| SRP219564 | KRT10 | 3858 | RNAseq | 3.0221 | 0.0015 | |
| TCGA | KRT10 | 3858 | RNAseq | 0.2892 | 0.0360 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by KRT10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRT10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRT10 | 3858 | 7 | 1 | 22 | |
| GSE20123 | KRT10 | 3858 | 7 | 1 | 22 | |
| GSE43470 | KRT10 | 3858 | 1 | 2 | 40 | |
| GSE46452 | KRT10 | 3858 | 34 | 0 | 25 | |
| GSE47630 | KRT10 | 3858 | 8 | 1 | 31 | |
| GSE54993 | KRT10 | 3858 | 3 | 4 | 63 | |
| GSE54994 | KRT10 | 3858 | 8 | 5 | 40 | |
| GSE60625 | KRT10 | 3858 | 4 | 0 | 7 | |
| GSE74703 | KRT10 | 3858 | 1 | 1 | 34 | |
| GSE74704 | KRT10 | 3858 | 5 | 1 | 14 | |
| TCGA | KRT10 | 3858 | 22 | 8 | 66 |
Total number of gains: 100; Total number of losses: 24; Total Number of normals: 364.
Somatic mutations of KRT10:
Generating mutation plots.
Highly correlated genes for KRT10:
Showing top 20/256 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRT10 | PANK3 | 0.691611 | 3 | 0 | 3 |
| KRT10 | GNPNAT1 | 0.667623 | 3 | 0 | 3 |
| KRT10 | SYT7 | 0.661375 | 3 | 0 | 3 |
| KRT10 | FBXO41 | 0.654745 | 5 | 0 | 3 |
| KRT10 | C14orf119 | 0.644291 | 3 | 0 | 3 |
| KRT10 | TMEM223 | 0.641316 | 4 | 0 | 3 |
| KRT10 | LANCL2 | 0.624328 | 4 | 0 | 3 |
| KRT10 | ANLN | 0.619546 | 5 | 0 | 3 |
| KRT10 | RCC1 | 0.618603 | 3 | 0 | 3 |
| KRT10 | REEP4 | 0.611962 | 4 | 0 | 3 |
| KRT10 | GFM1 | 0.610729 | 6 | 0 | 4 |
| KRT10 | AIMP2 | 0.609504 | 6 | 0 | 5 |
| KRT10 | GGCT | 0.605644 | 4 | 0 | 3 |
| KRT10 | B3GNT5 | 0.60102 | 4 | 0 | 3 |
| KRT10 | CEACAM19 | 0.600754 | 4 | 0 | 3 |
| KRT10 | BRMS1 | 0.599735 | 8 | 0 | 5 |
| KRT10 | WDR66 | 0.599328 | 6 | 0 | 4 |
| KRT10 | FRS2 | 0.598624 | 3 | 0 | 3 |
| KRT10 | PPP6R3 | 0.598604 | 4 | 0 | 3 |
| KRT10 | RFC2 | 0.598327 | 4 | 0 | 3 |
For details and further investigation, click here
