| Full name: peptidylprolyl isomerase like 4 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 6q25.1 | ||
| Entrez ID: 85313 | HGNC ID: HGNC:15702 | Ensembl Gene: ENSG00000131013 | OMIM ID: 607609 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of PPIL4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPIL4 | 85313 | 226472_at | 0.3674 | 0.3136 | |
| GSE26886 | PPIL4 | 85313 | 226472_at | 0.4124 | 0.0403 | |
| GSE45670 | PPIL4 | 85313 | 226472_at | 0.0826 | 0.6093 | |
| GSE53622 | PPIL4 | 85313 | 5168 | 0.2110 | 0.0001 | |
| GSE53624 | PPIL4 | 85313 | 5168 | 0.2477 | 0.0000 | |
| GSE63941 | PPIL4 | 85313 | 226472_at | -0.9291 | 0.0178 | |
| GSE77861 | PPIL4 | 85313 | 226472_at | 0.1501 | 0.5134 | |
| GSE97050 | PPIL4 | 85313 | A_23_P42507 | 0.0904 | 0.7482 | |
| SRP007169 | PPIL4 | 85313 | RNAseq | 0.3098 | 0.4040 | |
| SRP008496 | PPIL4 | 85313 | RNAseq | 0.7516 | 0.0029 | |
| SRP064894 | PPIL4 | 85313 | RNAseq | 0.2870 | 0.2610 | |
| SRP133303 | PPIL4 | 85313 | RNAseq | 0.3143 | 0.0000 | |
| SRP159526 | PPIL4 | 85313 | RNAseq | 0.0493 | 0.7768 | |
| SRP193095 | PPIL4 | 85313 | RNAseq | -0.0239 | 0.7766 | |
| SRP219564 | PPIL4 | 85313 | RNAseq | 0.0978 | 0.7153 | |
| TCGA | PPIL4 | 85313 | RNAseq | -0.0258 | 0.6182 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PPIL4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PPIL4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPIL4 | 85313 | 2 | 4 | 24 | |
| GSE20123 | PPIL4 | 85313 | 1 | 3 | 26 | |
| GSE43470 | PPIL4 | 85313 | 4 | 0 | 39 | |
| GSE46452 | PPIL4 | 85313 | 3 | 10 | 46 | |
| GSE47630 | PPIL4 | 85313 | 9 | 4 | 27 | |
| GSE54993 | PPIL4 | 85313 | 3 | 2 | 65 | |
| GSE54994 | PPIL4 | 85313 | 8 | 8 | 37 | |
| GSE60625 | PPIL4 | 85313 | 0 | 1 | 10 | |
| GSE74703 | PPIL4 | 85313 | 4 | 0 | 32 | |
| GSE74704 | PPIL4 | 85313 | 0 | 1 | 19 | |
| TCGA | PPIL4 | 85313 | 11 | 21 | 64 |
Total number of gains: 45; Total number of losses: 54; Total Number of normals: 389.
Somatic mutations of PPIL4:
Generating mutation plots.
Highly correlated genes for PPIL4:
Showing top 20/393 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPIL4 | TRIT1 | 0.798875 | 4 | 0 | 4 |
| PPIL4 | GAR1 | 0.773805 | 3 | 0 | 3 |
| PPIL4 | CCP110 | 0.764367 | 3 | 0 | 3 |
| PPIL4 | PANK3 | 0.755329 | 3 | 0 | 3 |
| PPIL4 | NOSIP | 0.755084 | 3 | 0 | 3 |
| PPIL4 | ZNF121 | 0.754957 | 3 | 0 | 3 |
| PPIL4 | EXOC8 | 0.75272 | 3 | 0 | 3 |
| PPIL4 | PCMT1 | 0.75102 | 4 | 0 | 4 |
| PPIL4 | ZMYND19 | 0.750912 | 3 | 0 | 3 |
| PPIL4 | ZNF35 | 0.748142 | 3 | 0 | 3 |
| PPIL4 | EIF4G3 | 0.744177 | 3 | 0 | 3 |
| PPIL4 | KDSR | 0.740424 | 3 | 0 | 3 |
| PPIL4 | SAR1A | 0.737558 | 3 | 0 | 3 |
| PPIL4 | WDR4 | 0.733369 | 3 | 0 | 3 |
| PPIL4 | GLOD4 | 0.732385 | 3 | 0 | 3 |
| PPIL4 | C8orf76 | 0.732258 | 3 | 0 | 3 |
| PPIL4 | YTHDF2 | 0.729201 | 3 | 0 | 3 |
| PPIL4 | ZNF407 | 0.725307 | 3 | 0 | 3 |
| PPIL4 | LTV1 | 0.720706 | 4 | 0 | 3 |
| PPIL4 | TMEM69 | 0.720503 | 4 | 0 | 4 |
For details and further investigation, click here
