| Full name: ribosome production factor 2 homolog | Alias Symbol: FLJ21087|bA397G5.4 | ||
| Type: protein-coding gene | Cytoband: 6q21 | ||
| Entrez ID: 84154 | HGNC ID: HGNC:20870 | Ensembl Gene: ENSG00000197498 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of RPF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPF2 | 84154 | 225866_at | 0.2051 | 0.7388 | |
| GSE26886 | RPF2 | 84154 | 225866_at | 0.0867 | 0.6271 | |
| GSE45670 | RPF2 | 84154 | 225866_at | 0.4095 | 0.0092 | |
| GSE53622 | RPF2 | 84154 | 53705 | 0.3521 | 0.0000 | |
| GSE53624 | RPF2 | 84154 | 76299 | 0.5371 | 0.0000 | |
| GSE63941 | RPF2 | 84154 | 225866_at | 0.7333 | 0.1440 | |
| GSE77861 | RPF2 | 84154 | 225866_at | 0.5893 | 0.0060 | |
| GSE97050 | RPF2 | 84154 | A_23_P19210 | 0.4209 | 0.2808 | |
| SRP007169 | RPF2 | 84154 | RNAseq | 0.8445 | 0.0165 | |
| SRP008496 | RPF2 | 84154 | RNAseq | 0.7432 | 0.0034 | |
| SRP064894 | RPF2 | 84154 | RNAseq | 0.2418 | 0.1505 | |
| SRP133303 | RPF2 | 84154 | RNAseq | 0.4027 | 0.0140 | |
| SRP159526 | RPF2 | 84154 | RNAseq | 0.1376 | 0.6163 | |
| SRP193095 | RPF2 | 84154 | RNAseq | 0.0600 | 0.6436 | |
| SRP219564 | RPF2 | 84154 | RNAseq | -0.2003 | 0.5318 | |
| TCGA | RPF2 | 84154 | RNAseq | 0.1942 | 0.0036 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RPF2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPF2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPF2 | 84154 | 2 | 3 | 25 | |
| GSE20123 | RPF2 | 84154 | 2 | 3 | 25 | |
| GSE43470 | RPF2 | 84154 | 3 | 1 | 39 | |
| GSE46452 | RPF2 | 84154 | 2 | 11 | 46 | |
| GSE47630 | RPF2 | 84154 | 9 | 4 | 27 | |
| GSE54993 | RPF2 | 84154 | 3 | 2 | 65 | |
| GSE54994 | RPF2 | 84154 | 8 | 8 | 37 | |
| GSE60625 | RPF2 | 84154 | 0 | 2 | 9 | |
| GSE74703 | RPF2 | 84154 | 2 | 1 | 33 | |
| GSE74704 | RPF2 | 84154 | 0 | 1 | 19 | |
| TCGA | RPF2 | 84154 | 6 | 23 | 67 |
Total number of gains: 37; Total number of losses: 59; Total Number of normals: 392.
Somatic mutations of RPF2:
Generating mutation plots.
Highly correlated genes for RPF2:
Showing top 20/1041 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPF2 | PGAP1 | 0.839971 | 3 | 0 | 3 |
| RPF2 | DSCC1 | 0.800694 | 3 | 0 | 3 |
| RPF2 | ZBED6 | 0.781542 | 3 | 0 | 3 |
| RPF2 | TUBA1B | 0.76929 | 3 | 0 | 3 |
| RPF2 | LYAR | 0.767565 | 8 | 0 | 8 |
| RPF2 | RACGAP1 | 0.761927 | 3 | 0 | 3 |
| RPF2 | ZNF121 | 0.75764 | 4 | 0 | 4 |
| RPF2 | ABCC4 | 0.75636 | 3 | 0 | 3 |
| RPF2 | ZNF417 | 0.752925 | 3 | 0 | 3 |
| RPF2 | MRPS28 | 0.748076 | 4 | 0 | 4 |
| RPF2 | RAD54L | 0.745938 | 3 | 0 | 3 |
| RPF2 | KPNA2 | 0.732246 | 3 | 0 | 3 |
| RPF2 | ZNF638 | 0.728067 | 3 | 0 | 3 |
| RPF2 | HNRNPU | 0.722531 | 3 | 0 | 3 |
| RPF2 | DDX59 | 0.721311 | 4 | 0 | 3 |
| RPF2 | MCM6 | 0.720813 | 5 | 0 | 5 |
| RPF2 | CDCA3 | 0.718521 | 5 | 0 | 5 |
| RPF2 | UBE2C | 0.717679 | 5 | 0 | 5 |
| RPF2 | PTPN2 | 0.717143 | 5 | 0 | 5 |
| RPF2 | DERL1 | 0.716859 | 3 | 0 | 3 |
For details and further investigation, click here
