CDYL

 

Full name: chromodomain Y like Alias Symbol: DKFZP586C1622|CDYL1
Type: protein-coding gene Cytoband: 6p25.1
Entrez ID: 9425 HGNC ID: HGNC:1811 Ensembl Gene: ENSG00000153046 OMIM ID: 603778
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of CDYL:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CDYL 9425 203098_at 0.1681 0.6123
GSE20347 CDYL 9425 203098_at 0.0926 0.5054
GSE23400 CDYL 9425 203098_at 0.0902 0.1520
GSE26886 CDYL 9425 203098_at -0.3327 0.1104
GSE29001 CDYL 9425 203098_at 0.0272 0.9411
GSE38129 CDYL 9425 203098_at 0.0944 0.3918
GSE45670 CDYL 9425 203098_at 0.1905 0.1900
GSE53622 CDYL 9425 34856 0.2100 0.0005
GSE53624 CDYL 9425 117532 0.0941 0.5139
GSE63941 CDYL 9425 203098_at -0.2813 0.3911
GSE77861 CDYL 9425 203098_at 0.2782 0.3105
GSE97050 CDYL 9425 A_23_P134078 0.0537 0.8437
SRP007169 CDYL 9425 RNAseq -0.9638 0.0193
SRP008496 CDYL 9425 RNAseq -0.8704 0.0002
SRP064894 CDYL 9425 RNAseq -0.0980 0.6025
SRP133303 CDYL 9425 RNAseq 0.0654 0.7131
SRP159526 CDYL 9425 RNAseq -0.0639 0.7920
SRP193095 CDYL 9425 RNAseq -0.1058 0.4153
SRP219564 CDYL 9425 RNAseq -0.7669 0.0058
TCGA CDYL 9425 RNAseq 0.1298 0.0162

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by CDYL expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of CDYL:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CDYL 9425 3 6 21
GSE20123 CDYL 9425 3 6 21
GSE43470 CDYL 9425 8 2 33
GSE46452 CDYL 9425 1 10 48
GSE47630 CDYL 9425 7 8 25
GSE54993 CDYL 9425 1 1 68
GSE54994 CDYL 9425 10 3 40
GSE60625 CDYL 9425 0 1 10
GSE74703 CDYL 9425 7 2 27
GSE74704 CDYL 9425 2 2 16
TCGA CDYL 9425 16 29 51

Total number of gains: 58; Total number of losses: 70; Total Number of normals: 360.  


 

Somatic mutations of CDYL:

 

Generating mutation plots.

 

Highly correlated genes for CDYL:

 

Showing top 20/371 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CDYLCIB10.802383303
CDYLPOLDIP20.798971303
CDYLUSP380.796146303
CDYLSMC50.779916303
CDYLMED80.767742303
CDYLANKRD13C0.760212303
CDYLSLC30A70.74979303
CDYLERGIC30.742042303
CDYLMTCH20.742007403
CDYLFBXO30.733099303
CDYLUBE2E20.726785303
CDYLSUZ120.724898303
CDYLTET20.724517303
CDYLPPP2R5E0.721819303
CDYLVPS290.721542303
CDYLPANK30.712059403
CDYLJMY0.709811404
CDYLARHGAP170.707686303
CDYLLRRC8B0.707332303
CDYLPSMC10.704936303

For details and further investigation, click here