| Full name: papilin, proteoglycan like sulfated glycoprotein | Alias Symbol: MGC50452 | ||
| Type: protein-coding gene | Cytoband: 14q24.2 | ||
| Entrez ID: 89932 | HGNC ID: HGNC:19262 | Ensembl Gene: ENSG00000100767 | OMIM ID: 617785 |
| Drug and gene relationship at DGIdb | |||
Expression of PAPLN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PAPLN | 89932 | 226435_at | 0.4708 | 0.4801 | |
| GSE26886 | PAPLN | 89932 | 226435_at | 1.6666 | 0.0107 | |
| GSE45670 | PAPLN | 89932 | 226435_at | 0.5139 | 0.1551 | |
| GSE53622 | PAPLN | 89932 | 117647 | 0.6625 | 0.0000 | |
| GSE53624 | PAPLN | 89932 | 117647 | 0.7006 | 0.0000 | |
| GSE63941 | PAPLN | 89932 | 226435_at | 0.6356 | 0.5380 | |
| GSE77861 | PAPLN | 89932 | 233896_s_at | -0.0873 | 0.4560 | |
| GSE97050 | PAPLN | 89932 | A_23_P333640 | 0.1990 | 0.4324 | |
| SRP007169 | PAPLN | 89932 | RNAseq | 0.6644 | 0.3002 | |
| SRP008496 | PAPLN | 89932 | RNAseq | 1.3618 | 0.0105 | |
| SRP064894 | PAPLN | 89932 | RNAseq | 1.0219 | 0.0000 | |
| SRP133303 | PAPLN | 89932 | RNAseq | 0.3619 | 0.1382 | |
| SRP159526 | PAPLN | 89932 | RNAseq | -0.0534 | 0.8659 | |
| SRP193095 | PAPLN | 89932 | RNAseq | 1.2035 | 0.0000 | |
| SRP219564 | PAPLN | 89932 | RNAseq | 0.4429 | 0.1167 | |
| TCGA | PAPLN | 89932 | RNAseq | 0.0427 | 0.7240 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by PAPLN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PAPLN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PAPLN | 89932 | 8 | 2 | 20 | |
| GSE20123 | PAPLN | 89932 | 8 | 2 | 20 | |
| GSE43470 | PAPLN | 89932 | 8 | 3 | 32 | |
| GSE46452 | PAPLN | 89932 | 16 | 3 | 40 | |
| GSE47630 | PAPLN | 89932 | 11 | 8 | 21 | |
| GSE54993 | PAPLN | 89932 | 3 | 8 | 59 | |
| GSE54994 | PAPLN | 89932 | 19 | 4 | 30 | |
| GSE60625 | PAPLN | 89932 | 0 | 2 | 9 | |
| GSE74703 | PAPLN | 89932 | 7 | 3 | 26 | |
| GSE74704 | PAPLN | 89932 | 3 | 2 | 15 | |
| TCGA | PAPLN | 89932 | 31 | 16 | 49 |
Total number of gains: 114; Total number of losses: 53; Total Number of normals: 321.
Somatic mutations of PAPLN:
Generating mutation plots.
Highly correlated genes for PAPLN:
Showing top 20/75 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PAPLN | KLHDC2 | 0.733887 | 3 | 0 | 3 |
| PAPLN | ZNF250 | 0.721161 | 3 | 0 | 3 |
| PAPLN | SART3 | 0.682862 | 3 | 0 | 3 |
| PAPLN | DCAF4 | 0.659282 | 4 | 0 | 3 |
| PAPLN | PTK2 | 0.62168 | 4 | 0 | 3 |
| PAPLN | MDK | 0.617598 | 3 | 0 | 3 |
| PAPLN | LINC01116 | 0.597288 | 6 | 0 | 5 |
| PAPLN | ASB2 | 0.591753 | 4 | 0 | 3 |
| PAPLN | ABCD4 | 0.590356 | 4 | 0 | 3 |
| PAPLN | STARD3NL | 0.583503 | 3 | 0 | 3 |
| PAPLN | C8orf82 | 0.575737 | 3 | 0 | 3 |
| PAPLN | ETV7 | 0.574449 | 4 | 0 | 3 |
| PAPLN | HPDL | 0.573808 | 4 | 0 | 3 |
| PAPLN | POGLUT1 | 0.569793 | 3 | 0 | 3 |
| PAPLN | MBD6 | 0.569514 | 3 | 0 | 3 |
| PAPLN | EAPP | 0.568164 | 3 | 0 | 3 |
| PAPLN | ZNF114 | 0.564419 | 3 | 0 | 3 |
| PAPLN | C14orf93 | 0.561361 | 4 | 0 | 3 |
| PAPLN | SLC2A9 | 0.560289 | 5 | 0 | 4 |
| PAPLN | TBC1D8 | 0.560151 | 3 | 0 | 3 |
For details and further investigation, click here
