| Full name: ETS variant transcription factor 7 | Alias Symbol: TEL2|TEL-2 | ||
| Type: protein-coding gene | Cytoband: 6p21.31 | ||
| Entrez ID: 51513 | HGNC ID: HGNC:18160 | Ensembl Gene: ENSG00000010030 | OMIM ID: 605255 |
| Drug and gene relationship at DGIdb | |||
Expression of ETV7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ETV7 | 51513 | 221680_s_at | 0.5032 | 0.3582 | |
| GSE20347 | ETV7 | 51513 | 221680_s_at | 0.1396 | 0.2440 | |
| GSE23400 | ETV7 | 51513 | 221680_s_at | 0.0120 | 0.8146 | |
| GSE26886 | ETV7 | 51513 | 221680_s_at | 0.4258 | 0.0097 | |
| GSE29001 | ETV7 | 51513 | 221680_s_at | 0.1534 | 0.4539 | |
| GSE38129 | ETV7 | 51513 | 221680_s_at | 0.2092 | 0.1269 | |
| GSE45670 | ETV7 | 51513 | 221680_s_at | 0.3250 | 0.1827 | |
| GSE53622 | ETV7 | 51513 | 87535 | 0.9212 | 0.0000 | |
| GSE53624 | ETV7 | 51513 | 112147 | 1.0078 | 0.0000 | |
| GSE63941 | ETV7 | 51513 | 221680_s_at | 0.4469 | 0.2461 | |
| GSE77861 | ETV7 | 51513 | 221680_s_at | 0.1607 | 0.2014 | |
| GSE97050 | ETV7 | 51513 | A_23_P42353 | 0.6138 | 0.2270 | |
| SRP007169 | ETV7 | 51513 | RNAseq | 0.9611 | 0.1833 | |
| SRP064894 | ETV7 | 51513 | RNAseq | 0.6658 | 0.0246 | |
| SRP133303 | ETV7 | 51513 | RNAseq | 1.4172 | 0.0001 | |
| SRP159526 | ETV7 | 51513 | RNAseq | 0.7387 | 0.1670 | |
| SRP193095 | ETV7 | 51513 | RNAseq | 0.6516 | 0.0009 | |
| SRP219564 | ETV7 | 51513 | RNAseq | 1.1707 | 0.1335 | |
| TCGA | ETV7 | 51513 | RNAseq | 0.6640 | 0.0001 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by ETV7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ETV7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ETV7 | 51513 | 6 | 0 | 24 | |
| GSE20123 | ETV7 | 51513 | 6 | 0 | 24 | |
| GSE43470 | ETV7 | 51513 | 5 | 1 | 37 | |
| GSE46452 | ETV7 | 51513 | 2 | 9 | 48 | |
| GSE47630 | ETV7 | 51513 | 8 | 4 | 28 | |
| GSE54993 | ETV7 | 51513 | 3 | 1 | 66 | |
| GSE54994 | ETV7 | 51513 | 10 | 5 | 38 | |
| GSE60625 | ETV7 | 51513 | 1 | 0 | 10 | |
| GSE74703 | ETV7 | 51513 | 5 | 0 | 31 | |
| GSE74704 | ETV7 | 51513 | 3 | 0 | 17 | |
| TCGA | ETV7 | 51513 | 15 | 15 | 66 |
Total number of gains: 64; Total number of losses: 35; Total Number of normals: 389.
Somatic mutations of ETV7:
Generating mutation plots.
Highly correlated genes for ETV7:
Showing top 20/236 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ETV7 | SSBP4 | 0.673871 | 3 | 0 | 3 |
| ETV7 | CXCL11 | 0.671226 | 9 | 0 | 8 |
| ETV7 | USP41 | 0.664421 | 3 | 0 | 3 |
| ETV7 | BATF2 | 0.658648 | 7 | 0 | 5 |
| ETV7 | CXCL10 | 0.638834 | 10 | 0 | 8 |
| ETV7 | FBXO6 | 0.634336 | 6 | 0 | 6 |
| ETV7 | EPSTI1 | 0.628148 | 6 | 0 | 5 |
| ETV7 | PBX4 | 0.627877 | 5 | 0 | 5 |
| ETV7 | RNF213 | 0.626934 | 4 | 0 | 3 |
| ETV7 | SOX30 | 0.626565 | 3 | 0 | 3 |
| ETV7 | SULT1A2 | 0.626148 | 3 | 0 | 3 |
| ETV7 | IL4I1 | 0.625658 | 7 | 0 | 6 |
| ETV7 | CEP131 | 0.622961 | 4 | 0 | 4 |
| ETV7 | GSK3A | 0.621608 | 4 | 0 | 3 |
| ETV7 | U2AF2 | 0.620787 | 3 | 0 | 3 |
| ETV7 | ADAP2 | 0.617577 | 3 | 0 | 3 |
| ETV7 | ICOS | 0.614871 | 4 | 0 | 4 |
| ETV7 | TAP1 | 0.614245 | 9 | 0 | 7 |
| ETV7 | DTX3L | 0.613184 | 7 | 0 | 5 |
| ETV7 | PCED1A | 0.612315 | 3 | 0 | 3 |
For details and further investigation, click here
