TBC1D19

 

Full name: TBC1 domain family member 19 Alias Symbol: FLJ11082
Type: protein-coding gene Cytoband: 4p15.2
Entrez ID: 55296 HGNC ID: HGNC:25624 Ensembl Gene: ENSG00000109680 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of TBC1D19:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TBC1D19 55296 220260_at 0.0316 0.9645
GSE20347 TBC1D19 55296 220260_at 0.1742 0.1666
GSE23400 TBC1D19 55296 220260_at -0.0251 0.5967
GSE26886 TBC1D19 55296 220260_at 0.1545 0.3621
GSE29001 TBC1D19 55296 220260_at 0.0581 0.8666
GSE38129 TBC1D19 55296 220260_at 0.2210 0.0345
GSE45670 TBC1D19 55296 220260_at 0.0592 0.7139
GSE53622 TBC1D19 55296 41058 0.1320 0.2334
GSE53624 TBC1D19 55296 41058 0.3435 0.0000
GSE63941 TBC1D19 55296 220260_at -3.1145 0.0003
GSE77861 TBC1D19 55296 220260_at -0.1513 0.1473
GSE97050 TBC1D19 55296 A_23_P136196 -0.0871 0.6706
SRP007169 TBC1D19 55296 RNAseq 0.0790 0.8793
SRP064894 TBC1D19 55296 RNAseq 0.6431 0.0030
SRP133303 TBC1D19 55296 RNAseq 0.1628 0.4190
SRP159526 TBC1D19 55296 RNAseq 0.7173 0.0097
SRP193095 TBC1D19 55296 RNAseq 0.1637 0.1817
SRP219564 TBC1D19 55296 RNAseq 0.2221 0.5635
TCGA TBC1D19 55296 RNAseq -0.1362 0.1567

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by TBC1D19 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of TBC1D19:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TBC1D19 55296 0 18 12
GSE20123 TBC1D19 55296 0 16 14
GSE43470 TBC1D19 55296 0 14 29
GSE46452 TBC1D19 55296 1 36 22
GSE47630 TBC1D19 55296 1 19 20
GSE54993 TBC1D19 55296 9 0 61
GSE54994 TBC1D19 55296 5 11 37
GSE60625 TBC1D19 55296 0 0 11
GSE74703 TBC1D19 55296 0 12 24
GSE74704 TBC1D19 55296 0 10 10
TCGA TBC1D19 55296 11 47 38

Total number of gains: 27; Total number of losses: 183; Total Number of normals: 278.  


 

Somatic mutations of TBC1D19:

 

Generating mutation plots.

 

Highly correlated genes for TBC1D19:

 

Showing top 20/313 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TBC1D19ATL10.802466303
TBC1D19FAM98B0.778703303
TBC1D19MTMR90.770706303
TBC1D19HGF0.766379303
TBC1D19NKIRAS10.760262303
TBC1D19SAR1A0.759822303
TBC1D19PAQR30.744579303
TBC1D19SNX180.739366303
TBC1D19PRICKLE20.736626403
TBC1D19UBE2Q20.73386403
TBC1D19GLIS30.730259303
TBC1D19IGFBP60.729557303
TBC1D19DIXDC10.728797303
TBC1D19PXK0.724811303
TBC1D19FAM155A0.720661303
TBC1D19ZNF5780.713692303
TBC1D19SH3RF30.71256303
TBC1D19ZNF7170.709035303
TBC1D19ALDH1L20.706742303
TBC1D19PLSCR40.703173303

For details and further investigation, click here