| Full name: neuroplastin | Alias Symbol: SDR1|GP55|GP65|np65|np55 | ||
| Type: protein-coding gene | Cytoband: 15q24.1 | ||
| Entrez ID: 27020 | HGNC ID: HGNC:17867 | Ensembl Gene: ENSG00000156642 | OMIM ID: 612820 |
| Drug and gene relationship at DGIdb | |||
Expression of NPTN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NPTN | 27020 | 202228_s_at | -0.2360 | 0.6087 | |
| GSE20347 | NPTN | 27020 | 202228_s_at | 0.0450 | 0.8325 | |
| GSE23400 | NPTN | 27020 | 202228_s_at | 0.0613 | 0.5744 | |
| GSE26886 | NPTN | 27020 | 202228_s_at | -0.4680 | 0.0238 | |
| GSE29001 | NPTN | 27020 | 202228_s_at | 0.0174 | 0.9659 | |
| GSE38129 | NPTN | 27020 | 202228_s_at | -0.0676 | 0.6439 | |
| GSE45670 | NPTN | 27020 | 202228_s_at | -0.3292 | 0.0034 | |
| GSE53622 | NPTN | 27020 | 40807 | -0.4384 | 0.0000 | |
| GSE53624 | NPTN | 27020 | 57232 | -0.2346 | 0.0000 | |
| GSE63941 | NPTN | 27020 | 202228_s_at | -0.6209 | 0.0905 | |
| GSE77861 | NPTN | 27020 | 202228_s_at | -0.0753 | 0.7667 | |
| GSE97050 | NPTN | 27020 | A_24_P95822 | -0.6277 | 0.0866 | |
| SRP007169 | NPTN | 27020 | RNAseq | -0.8572 | 0.0099 | |
| SRP008496 | NPTN | 27020 | RNAseq | -0.7777 | 0.0000 | |
| SRP064894 | NPTN | 27020 | RNAseq | -0.3154 | 0.0611 | |
| SRP133303 | NPTN | 27020 | RNAseq | 0.1308 | 0.4532 | |
| SRP159526 | NPTN | 27020 | RNAseq | -0.2868 | 0.3843 | |
| SRP193095 | NPTN | 27020 | RNAseq | -0.1327 | 0.2792 | |
| SRP219564 | NPTN | 27020 | RNAseq | -0.2270 | 0.5888 | |
| TCGA | NPTN | 27020 | RNAseq | -0.0526 | 0.2545 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NPTN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NPTN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NPTN | 27020 | 8 | 0 | 22 | |
| GSE20123 | NPTN | 27020 | 8 | 0 | 22 | |
| GSE43470 | NPTN | 27020 | 4 | 6 | 33 | |
| GSE46452 | NPTN | 27020 | 3 | 7 | 49 | |
| GSE47630 | NPTN | 27020 | 8 | 10 | 22 | |
| GSE54993 | NPTN | 27020 | 5 | 6 | 59 | |
| GSE54994 | NPTN | 27020 | 5 | 8 | 40 | |
| GSE60625 | NPTN | 27020 | 4 | 0 | 7 | |
| GSE74703 | NPTN | 27020 | 4 | 3 | 29 | |
| GSE74704 | NPTN | 27020 | 4 | 0 | 16 | |
| TCGA | NPTN | 27020 | 12 | 15 | 69 |
Total number of gains: 65; Total number of losses: 55; Total Number of normals: 368.
Somatic mutations of NPTN:
Generating mutation plots.
Highly correlated genes for NPTN:
Showing top 20/723 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NPTN | PRICKLE2 | 0.763869 | 5 | 0 | 5 |
| NPTN | UGP2 | 0.754275 | 4 | 0 | 4 |
| NPTN | DAZAP2 | 0.749702 | 3 | 0 | 3 |
| NPTN | RHBDD1 | 0.741422 | 3 | 0 | 3 |
| NPTN | RASSF3 | 0.729961 | 4 | 0 | 4 |
| NPTN | SLC30A9 | 0.726346 | 3 | 0 | 3 |
| NPTN | HCFC2 | 0.721602 | 3 | 0 | 3 |
| NPTN | NIPAL3 | 0.720279 | 3 | 0 | 3 |
| NPTN | GTF2B | 0.719379 | 3 | 0 | 3 |
| NPTN | DLD | 0.708246 | 4 | 0 | 4 |
| NPTN | HIPK1 | 0.70614 | 4 | 0 | 4 |
| NPTN | GHITM | 0.700818 | 3 | 0 | 3 |
| NPTN | ST13 | 0.697429 | 4 | 0 | 4 |
| NPTN | CALCOCO2 | 0.697152 | 4 | 0 | 3 |
| NPTN | FBXO30 | 0.694991 | 3 | 0 | 3 |
| NPTN | SOX17 | 0.691322 | 3 | 0 | 3 |
| NPTN | PAQR3 | 0.689933 | 4 | 0 | 4 |
| NPTN | ZRANB1 | 0.687328 | 3 | 0 | 3 |
| NPTN | NKAPL | 0.686453 | 3 | 0 | 3 |
| NPTN | FKBP7 | 0.685579 | 3 | 0 | 3 |
For details and further investigation, click here
