| Full name: prostate and breast cancer overexpressed 1 | Alias Symbol: UC28|UROC28 | ||
| Type: protein-coding gene | Cytoband: 6q23.3 | ||
| Entrez ID: 59351 | HGNC ID: HGNC:21079 | Ensembl Gene: ENSG00000254440 | OMIM ID: 605669 |
| Drug and gene relationship at DGIdb | |||
Expression of PBOV1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PBOV1 | 59351 | 224257_s_at | 0.0311 | 0.9196 | |
| GSE20347 | PBOV1 | 59351 | 208329_at | -0.0567 | 0.2719 | |
| GSE23400 | PBOV1 | 59351 | 208329_at | -0.1152 | 0.0001 | |
| GSE26886 | PBOV1 | 59351 | 224257_s_at | -0.1372 | 0.0985 | |
| GSE29001 | PBOV1 | 59351 | 208329_at | -0.1992 | 0.0668 | |
| GSE38129 | PBOV1 | 59351 | 208329_at | -0.1153 | 0.0407 | |
| GSE45670 | PBOV1 | 59351 | 224257_s_at | 0.0903 | 0.2477 | |
| GSE53622 | PBOV1 | 59351 | 128105 | -0.3625 | 0.0002 | |
| GSE53624 | PBOV1 | 59351 | 128105 | -0.3675 | 0.0003 | |
| GSE63941 | PBOV1 | 59351 | 208329_at | -0.0122 | 0.9240 | |
| GSE77861 | PBOV1 | 59351 | 224257_s_at | 0.0319 | 0.8303 | |
| SRP133303 | PBOV1 | 59351 | RNAseq | -0.1413 | 0.7299 | |
| TCGA | PBOV1 | 59351 | RNAseq | -3.0974 | 0.0016 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PBOV1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PBOV1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PBOV1 | 59351 | 3 | 4 | 23 | |
| GSE20123 | PBOV1 | 59351 | 3 | 3 | 24 | |
| GSE43470 | PBOV1 | 59351 | 5 | 0 | 38 | |
| GSE46452 | PBOV1 | 59351 | 3 | 10 | 46 | |
| GSE47630 | PBOV1 | 59351 | 9 | 4 | 27 | |
| GSE54993 | PBOV1 | 59351 | 3 | 2 | 65 | |
| GSE54994 | PBOV1 | 59351 | 8 | 8 | 37 | |
| GSE60625 | PBOV1 | 59351 | 0 | 1 | 10 | |
| GSE74703 | PBOV1 | 59351 | 4 | 0 | 32 | |
| GSE74704 | PBOV1 | 59351 | 1 | 1 | 18 | |
| TCGA | PBOV1 | 59351 | 11 | 17 | 68 |
Total number of gains: 50; Total number of losses: 50; Total Number of normals: 388.
Somatic mutations of PBOV1:
Generating mutation plots.
Highly correlated genes for PBOV1:
Showing top 20/486 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PBOV1 | PYHIN1 | 0.717543 | 4 | 0 | 4 |
| PBOV1 | FCRL5 | 0.691078 | 3 | 0 | 3 |
| PBOV1 | GRIP2 | 0.688326 | 5 | 0 | 5 |
| PBOV1 | ZNF671 | 0.68066 | 3 | 0 | 3 |
| PBOV1 | GPR31 | 0.680358 | 4 | 0 | 4 |
| PBOV1 | TTBK1 | 0.676391 | 3 | 0 | 3 |
| PBOV1 | CD160 | 0.676046 | 3 | 0 | 3 |
| PBOV1 | ASIC4 | 0.667722 | 3 | 0 | 3 |
| PBOV1 | IL2RG | 0.663025 | 3 | 0 | 3 |
| PBOV1 | HOXA3 | 0.661941 | 3 | 0 | 3 |
| PBOV1 | DPEP1 | 0.652169 | 3 | 0 | 3 |
| PBOV1 | GDF2 | 0.647603 | 3 | 0 | 3 |
| PBOV1 | TAPT1 | 0.646295 | 4 | 0 | 3 |
| PBOV1 | FSCN3 | 0.645998 | 4 | 0 | 4 |
| PBOV1 | DUSP13 | 0.64455 | 3 | 0 | 3 |
| PBOV1 | RAB3IL1 | 0.640459 | 4 | 0 | 4 |
| PBOV1 | SIT1 | 0.640142 | 4 | 0 | 4 |
| PBOV1 | KLF1 | 0.636403 | 3 | 0 | 3 |
| PBOV1 | ADRA1D | 0.635843 | 3 | 0 | 3 |
| PBOV1 | C20orf203 | 0.634217 | 3 | 0 | 3 |
For details and further investigation, click here
