| Full name: Kruppel like factor 1 | Alias Symbol: EKLF | ||
| Type: protein-coding gene | Cytoband: 19p13.13 | ||
| Entrez ID: 10661 | HGNC ID: HGNC:6345 | Ensembl Gene: ENSG00000105610 | OMIM ID: 600599 |
Expression of KLF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KLF1 | 10661 | 210504_at | -0.0771 | 0.7630 | |
| GSE20347 | KLF1 | 10661 | 210504_at | -0.0806 | 0.2791 | |
| GSE23400 | KLF1 | 10661 | 210504_at | -0.0668 | 0.0291 | |
| GSE26886 | KLF1 | 10661 | 210504_at | 0.3205 | 0.0196 | |
| GSE29001 | KLF1 | 10661 | 210504_at | -0.1191 | 0.2613 | |
| GSE38129 | KLF1 | 10661 | 210504_at | -0.1428 | 0.0627 | |
| GSE45670 | KLF1 | 10661 | 210504_at | 0.0668 | 0.4888 | |
| GSE63941 | KLF1 | 10661 | 210504_at | -0.0264 | 0.8979 | |
| GSE77861 | KLF1 | 10661 | 210504_at | 0.0208 | 0.8743 | |
| TCGA | KLF1 | 10661 | RNAseq | 1.8090 | 0.0196 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by KLF1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of KLF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KLF1 | 10661 | 4 | 2 | 24 | |
| GSE20123 | KLF1 | 10661 | 3 | 1 | 26 | |
| GSE43470 | KLF1 | 10661 | 2 | 6 | 35 | |
| GSE46452 | KLF1 | 10661 | 47 | 1 | 11 | |
| GSE47630 | KLF1 | 10661 | 4 | 7 | 29 | |
| GSE54993 | KLF1 | 10661 | 16 | 3 | 51 | |
| GSE54994 | KLF1 | 10661 | 8 | 13 | 32 | |
| GSE60625 | KLF1 | 10661 | 9 | 0 | 2 | |
| GSE74703 | KLF1 | 10661 | 2 | 4 | 30 | |
| GSE74704 | KLF1 | 10661 | 0 | 1 | 19 | |
| TCGA | KLF1 | 10661 | 16 | 13 | 67 |
Total number of gains: 111; Total number of losses: 51; Total Number of normals: 326.
Somatic mutations of KLF1:
Generating mutation plots.
Highly correlated genes for KLF1:
Showing top 20/686 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KLF1 | C3orf36 | 0.701726 | 5 | 0 | 5 |
| KLF1 | CYP2A6 | 0.689966 | 4 | 0 | 4 |
| KLF1 | LINC00474 | 0.687509 | 3 | 0 | 3 |
| KLF1 | NOS1 | 0.686242 | 4 | 0 | 4 |
| KLF1 | UPK2 | 0.680033 | 4 | 0 | 4 |
| KLF1 | FOLH1 | 0.679597 | 3 | 0 | 3 |
| KLF1 | AMACR | 0.678609 | 3 | 0 | 3 |
| KLF1 | MASP1 | 0.678422 | 4 | 0 | 4 |
| KLF1 | CER1 | 0.674025 | 3 | 0 | 3 |
| KLF1 | OR3A3 | 0.673653 | 5 | 0 | 4 |
| KLF1 | HABP2 | 0.670927 | 3 | 0 | 3 |
| KLF1 | G6PC2 | 0.67034 | 4 | 0 | 4 |
| KLF1 | FN3K | 0.667559 | 4 | 0 | 4 |
| KLF1 | SLC4A1 | 0.667115 | 3 | 0 | 3 |
| KLF1 | IFNA21 | 0.664219 | 4 | 0 | 4 |
| KLF1 | GPR12 | 0.659986 | 4 | 0 | 4 |
| KLF1 | RPS6KA6 | 0.659009 | 3 | 0 | 3 |
| KLF1 | HSD3B2 | 0.65381 | 3 | 0 | 3 |
| KLF1 | OR10C1 | 0.653104 | 3 | 0 | 3 |
| KLF1 | CTNNA3 | 0.651605 | 5 | 0 | 5 |
For details and further investigation, click here
