| Full name: interleukin 2 receptor subunit gamma | Alias Symbol: CD132 | ||
| Type: protein-coding gene | Cytoband: Xq13.1 | ||
| Entrez ID: 3561 | HGNC ID: HGNC:6010 | Ensembl Gene: ENSG00000147168 | OMIM ID: 308380 |
| Drug and gene relationship at DGIdb | |||
IL2RG involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04151 | PI3K-Akt signaling pathway | |
| hsa04630 | Jak-STAT signaling pathway | |
| hsa05162 | Measles | |
| hsa05166 | HTLV-I infection | |
| hsa05321 | Inflammatory bowel disease (IBD) |
Expression of IL2RG:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IL2RG | 3561 | 204116_at | 0.3975 | 0.7749 | |
| GSE20347 | IL2RG | 3561 | 204116_at | -0.1681 | 0.5437 | |
| GSE23400 | IL2RG | 3561 | 204116_at | -0.0413 | 0.6968 | |
| GSE26886 | IL2RG | 3561 | 204116_at | -0.3701 | 0.0727 | |
| GSE29001 | IL2RG | 3561 | 204116_at | -0.4095 | 0.0553 | |
| GSE38129 | IL2RG | 3561 | 204116_at | -0.1114 | 0.6443 | |
| GSE45670 | IL2RG | 3561 | 204116_at | -0.0460 | 0.7167 | |
| GSE53622 | IL2RG | 3561 | 38253 | 0.1880 | 0.2895 | |
| GSE53624 | IL2RG | 3561 | 40375 | -0.0408 | 0.7670 | |
| GSE63941 | IL2RG | 3561 | 204116_at | 0.4189 | 0.0086 | |
| GSE77861 | IL2RG | 3561 | 204116_at | -0.3297 | 0.0248 | |
| GSE97050 | IL2RG | 3561 | A_23_P148473 | 1.1142 | 0.1934 | |
| SRP007169 | IL2RG | 3561 | RNAseq | 0.5309 | 0.4837 | |
| SRP008496 | IL2RG | 3561 | RNAseq | -0.3549 | 0.4933 | |
| SRP064894 | IL2RG | 3561 | RNAseq | 0.1598 | 0.5020 | |
| SRP133303 | IL2RG | 3561 | RNAseq | -0.0136 | 0.9523 | |
| SRP159526 | IL2RG | 3561 | RNAseq | -0.6812 | 0.4432 | |
| SRP193095 | IL2RG | 3561 | RNAseq | -0.3774 | 0.2110 | |
| SRP219564 | IL2RG | 3561 | RNAseq | 0.7293 | 0.1934 | |
| TCGA | IL2RG | 3561 | RNAseq | 0.0549 | 0.7066 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by IL2RG expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IL2RG:
No record found for this gene.
Somatic mutations of IL2RG:
Generating mutation plots.
Highly correlated genes for IL2RG:
Showing top 20/623 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IL2RG | TIGIT | 0.811911 | 4 | 0 | 4 |
| IL2RG | FCRL3 | 0.791171 | 4 | 0 | 4 |
| IL2RG | JAK3 | 0.784843 | 6 | 0 | 5 |
| IL2RG | ATXN8OS | 0.784642 | 3 | 0 | 3 |
| IL2RG | CD3D | 0.767806 | 10 | 0 | 9 |
| IL2RG | CYTIP | 0.76371 | 7 | 0 | 7 |
| IL2RG | GPRIN3 | 0.759599 | 3 | 0 | 3 |
| IL2RG | CORO1B | 0.757562 | 3 | 0 | 3 |
| IL2RG | POU2AF1 | 0.751382 | 3 | 0 | 3 |
| IL2RG | GZMA | 0.746365 | 7 | 0 | 6 |
| IL2RG | ARHGAP9 | 0.741431 | 5 | 0 | 4 |
| IL2RG | SNX20 | 0.73022 | 6 | 0 | 5 |
| IL2RG | CD3E | 0.728562 | 11 | 0 | 9 |
| IL2RG | PSMB8-AS1 | 0.727317 | 3 | 0 | 3 |
| IL2RG | GIMAP2 | 0.726023 | 4 | 0 | 4 |
| IL2RG | IL12RB1 | 0.719645 | 7 | 0 | 6 |
| IL2RG | EXOC3L2 | 0.71905 | 3 | 0 | 3 |
| IL2RG | SLAMF6 | 0.71869 | 6 | 0 | 5 |
| IL2RG | EPN1 | 0.718255 | 3 | 0 | 3 |
| IL2RG | SASH3 | 0.717468 | 9 | 0 | 8 |
For details and further investigation, click here
