| Full name: transmembrane protein 135 | Alias Symbol: FLJ22104 | ||
| Type: protein-coding gene | Cytoband: 11q14.2 | ||
| Entrez ID: 65084 | HGNC ID: HGNC:26167 | Ensembl Gene: ENSG00000166575 | OMIM ID: 616360 |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM135:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM135 | 65084 | 222209_s_at | 0.4646 | 0.3264 | |
| GSE20347 | TMEM135 | 65084 | 222209_s_at | 1.1720 | 0.0004 | |
| GSE23400 | TMEM135 | 65084 | 222209_s_at | 0.5177 | 0.0000 | |
| GSE26886 | TMEM135 | 65084 | 222209_s_at | 0.4863 | 0.1774 | |
| GSE29001 | TMEM135 | 65084 | 222209_s_at | 0.6577 | 0.0429 | |
| GSE38129 | TMEM135 | 65084 | 222209_s_at | 0.9198 | 0.0002 | |
| GSE45670 | TMEM135 | 65084 | 222209_s_at | 0.2386 | 0.3521 | |
| GSE53622 | TMEM135 | 65084 | 66356 | 0.1181 | 0.4060 | |
| GSE53624 | TMEM135 | 65084 | 66356 | 0.1715 | 0.0639 | |
| GSE63941 | TMEM135 | 65084 | 222209_s_at | 0.0739 | 0.9027 | |
| GSE77861 | TMEM135 | 65084 | 222209_s_at | 0.6866 | 0.0250 | |
| GSE97050 | TMEM135 | 65084 | A_24_P127075 | -0.3843 | 0.1995 | |
| SRP007169 | TMEM135 | 65084 | RNAseq | 1.1775 | 0.0463 | |
| SRP008496 | TMEM135 | 65084 | RNAseq | 0.6806 | 0.0504 | |
| SRP064894 | TMEM135 | 65084 | RNAseq | 0.6718 | 0.0138 | |
| SRP133303 | TMEM135 | 65084 | RNAseq | 0.2331 | 0.0964 | |
| SRP159526 | TMEM135 | 65084 | RNAseq | 0.2911 | 0.4334 | |
| SRP193095 | TMEM135 | 65084 | RNAseq | -0.0221 | 0.9016 | |
| SRP219564 | TMEM135 | 65084 | RNAseq | 0.0860 | 0.7608 | |
| TCGA | TMEM135 | 65084 | RNAseq | -0.0463 | 0.5110 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by TMEM135 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM135:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM135 | 65084 | 4 | 9 | 17 | |
| GSE20123 | TMEM135 | 65084 | 4 | 9 | 17 | |
| GSE43470 | TMEM135 | 65084 | 3 | 4 | 36 | |
| GSE46452 | TMEM135 | 65084 | 6 | 23 | 30 | |
| GSE47630 | TMEM135 | 65084 | 2 | 19 | 19 | |
| GSE54993 | TMEM135 | 65084 | 8 | 2 | 60 | |
| GSE54994 | TMEM135 | 65084 | 5 | 19 | 29 | |
| GSE60625 | TMEM135 | 65084 | 0 | 3 | 8 | |
| GSE74703 | TMEM135 | 65084 | 2 | 3 | 31 | |
| GSE74704 | TMEM135 | 65084 | 3 | 6 | 11 | |
| TCGA | TMEM135 | 65084 | 16 | 38 | 42 |
Total number of gains: 53; Total number of losses: 135; Total Number of normals: 300.
Somatic mutations of TMEM135:
Generating mutation plots.
Highly correlated genes for TMEM135:
Showing top 20/1059 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM135 | NOM1 | 0.836062 | 3 | 0 | 3 |
| TMEM135 | MRPS5 | 0.80038 | 3 | 0 | 3 |
| TMEM135 | WDR75 | 0.792354 | 3 | 0 | 3 |
| TMEM135 | NUP35 | 0.786683 | 3 | 0 | 3 |
| TMEM135 | PIAS4 | 0.783677 | 3 | 0 | 3 |
| TMEM135 | PCGF6 | 0.778626 | 3 | 0 | 3 |
| TMEM135 | NEDD1 | 0.770152 | 4 | 0 | 4 |
| TMEM135 | MRPL45 | 0.752693 | 3 | 0 | 3 |
| TMEM135 | LTV1 | 0.747486 | 3 | 0 | 3 |
| TMEM135 | PARP8 | 0.744211 | 3 | 0 | 3 |
| TMEM135 | TGFBR1 | 0.743868 | 3 | 0 | 3 |
| TMEM135 | SLC25A21 | 0.729682 | 3 | 0 | 3 |
| TMEM135 | MIPOL1 | 0.725179 | 3 | 0 | 3 |
| TMEM135 | SLC41A1 | 0.719105 | 3 | 0 | 3 |
| TMEM135 | FAM98B | 0.718264 | 3 | 0 | 3 |
| TMEM135 | TAOK1 | 0.716624 | 3 | 0 | 3 |
| TMEM135 | ZSCAN29 | 0.71613 | 4 | 0 | 3 |
| TMEM135 | ALKBH6 | 0.715453 | 3 | 0 | 3 |
| TMEM135 | TAP1 | 0.714749 | 3 | 0 | 3 |
| TMEM135 | ZCCHC7 | 0.713331 | 3 | 0 | 3 |
For details and further investigation, click here
