| Full name: microtubule associated serine/threonine kinase like | Alias Symbol: FLJ14813|THC2|Gwl | ||
| Type: protein-coding gene | Cytoband: 10p12.1 | ||
| Entrez ID: 84930 | HGNC ID: HGNC:19042 | Ensembl Gene: ENSG00000120539 | OMIM ID: 608221 |
| Drug and gene relationship at DGIdb | |||
Expression of MASTL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MASTL | 84930 | 228468_at | 0.7773 | 0.1378 | |
| GSE26886 | MASTL | 84930 | 228468_at | 1.1090 | 0.0030 | |
| GSE45670 | MASTL | 84930 | 228468_at | 0.7650 | 0.0000 | |
| GSE53622 | MASTL | 84930 | 47148 | 0.8589 | 0.0000 | |
| GSE53624 | MASTL | 84930 | 47148 | 0.9666 | 0.0000 | |
| GSE63941 | MASTL | 84930 | 228468_at | 0.7648 | 0.1775 | |
| GSE77861 | MASTL | 84930 | 228468_at | 0.3329 | 0.3905 | |
| GSE97050 | MASTL | 84930 | A_24_P258051 | 0.9373 | 0.1049 | |
| SRP007169 | MASTL | 84930 | RNAseq | 0.7443 | 0.0739 | |
| SRP008496 | MASTL | 84930 | RNAseq | 0.4091 | 0.1311 | |
| SRP064894 | MASTL | 84930 | RNAseq | 0.4077 | 0.0608 | |
| SRP133303 | MASTL | 84930 | RNAseq | 0.5162 | 0.0080 | |
| SRP159526 | MASTL | 84930 | RNAseq | 0.1888 | 0.4226 | |
| SRP193095 | MASTL | 84930 | RNAseq | 0.4066 | 0.0026 | |
| SRP219564 | MASTL | 84930 | RNAseq | 0.1931 | 0.6897 | |
| TCGA | MASTL | 84930 | RNAseq | 0.4290 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MASTL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MASTL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MASTL | 84930 | 5 | 7 | 18 | |
| GSE20123 | MASTL | 84930 | 5 | 6 | 19 | |
| GSE43470 | MASTL | 84930 | 3 | 4 | 36 | |
| GSE46452 | MASTL | 84930 | 1 | 14 | 44 | |
| GSE47630 | MASTL | 84930 | 5 | 15 | 20 | |
| GSE54993 | MASTL | 84930 | 9 | 0 | 61 | |
| GSE54994 | MASTL | 84930 | 3 | 10 | 40 | |
| GSE60625 | MASTL | 84930 | 0 | 0 | 11 | |
| GSE74703 | MASTL | 84930 | 2 | 2 | 32 | |
| GSE74704 | MASTL | 84930 | 0 | 5 | 15 | |
| TCGA | MASTL | 84930 | 18 | 24 | 54 |
Total number of gains: 51; Total number of losses: 87; Total Number of normals: 350.
Somatic mutations of MASTL:
Generating mutation plots.
Highly correlated genes for MASTL:
Showing top 20/1538 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MASTL | TRAF7 | 0.801449 | 3 | 0 | 3 |
| MASTL | MGAT2 | 0.785361 | 3 | 0 | 3 |
| MASTL | FAF2 | 0.783277 | 3 | 0 | 3 |
| MASTL | RCN2 | 0.769412 | 4 | 0 | 4 |
| MASTL | SMC6 | 0.768882 | 5 | 0 | 5 |
| MASTL | DSCC1 | 0.765745 | 6 | 0 | 6 |
| MASTL | PLAGL2 | 0.757538 | 3 | 0 | 3 |
| MASTL | NUSAP1 | 0.75693 | 8 | 0 | 7 |
| MASTL | RFWD3 | 0.755977 | 5 | 0 | 5 |
| MASTL | KIF23 | 0.754879 | 8 | 0 | 8 |
| MASTL | RRAS2 | 0.753817 | 3 | 0 | 3 |
| MASTL | MAP4K4 | 0.753022 | 3 | 0 | 3 |
| MASTL | CCNB2 | 0.748612 | 7 | 0 | 7 |
| MASTL | TMEM17 | 0.747879 | 3 | 0 | 3 |
| MASTL | KNSTRN | 0.744684 | 7 | 0 | 6 |
| MASTL | INTS10 | 0.743318 | 3 | 0 | 3 |
| MASTL | R3HDM1 | 0.738689 | 6 | 0 | 6 |
| MASTL | RAN | 0.738167 | 5 | 0 | 5 |
| MASTL | SPNS1 | 0.737736 | 3 | 0 | 3 |
| MASTL | CDCA3 | 0.73772 | 8 | 0 | 8 |
For details and further investigation, click here
