| Full name: programmed cell death 5 | Alias Symbol: TFAR19|MGC9294 | ||
| Type: protein-coding gene | Cytoband: 19q13.11 | ||
| Entrez ID: 9141 | HGNC ID: HGNC:8764 | Ensembl Gene: ENSG00000105185 | OMIM ID: 604583 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PDCD5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PDCD5 | 9141 | 219275_at | 0.5577 | 0.1083 | |
| GSE20347 | PDCD5 | 9141 | 219275_at | 0.5173 | 0.0126 | |
| GSE23400 | PDCD5 | 9141 | 219275_at | 0.4565 | 0.0000 | |
| GSE26886 | PDCD5 | 9141 | 219275_at | 0.9707 | 0.0000 | |
| GSE29001 | PDCD5 | 9141 | 219275_at | 0.4574 | 0.0338 | |
| GSE38129 | PDCD5 | 9141 | 219275_at | 0.6997 | 0.0000 | |
| GSE45670 | PDCD5 | 9141 | 219275_at | 0.3430 | 0.0770 | |
| GSE53622 | PDCD5 | 9141 | 60022 | 0.4238 | 0.0000 | |
| GSE53624 | PDCD5 | 9141 | 60022 | 0.7934 | 0.0000 | |
| GSE63941 | PDCD5 | 9141 | 219275_at | -0.2089 | 0.7276 | |
| GSE77861 | PDCD5 | 9141 | 219275_at | 0.3204 | 0.1408 | |
| GSE97050 | PDCD5 | 9141 | A_24_P339611 | 0.6981 | 0.1931 | |
| SRP007169 | PDCD5 | 9141 | RNAseq | 1.1455 | 0.0471 | |
| SRP008496 | PDCD5 | 9141 | RNAseq | 1.0480 | 0.0202 | |
| SRP064894 | PDCD5 | 9141 | RNAseq | 0.5505 | 0.0108 | |
| SRP133303 | PDCD5 | 9141 | RNAseq | 0.6932 | 0.0302 | |
| SRP159526 | PDCD5 | 9141 | RNAseq | 0.3586 | 0.0705 | |
| SRP193095 | PDCD5 | 9141 | RNAseq | 0.0357 | 0.8287 | |
| SRP219564 | PDCD5 | 9141 | RNAseq | 0.3006 | 0.3065 | |
| TCGA | PDCD5 | 9141 | RNAseq | 0.2472 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by PDCD5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PDCD5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PDCD5 | 9141 | 7 | 6 | 17 | |
| GSE20123 | PDCD5 | 9141 | 7 | 5 | 18 | |
| GSE43470 | PDCD5 | 9141 | 5 | 6 | 32 | |
| GSE46452 | PDCD5 | 9141 | 47 | 1 | 11 | |
| GSE47630 | PDCD5 | 9141 | 8 | 6 | 26 | |
| GSE54993 | PDCD5 | 9141 | 17 | 3 | 50 | |
| GSE54994 | PDCD5 | 9141 | 7 | 9 | 37 | |
| GSE60625 | PDCD5 | 9141 | 9 | 0 | 2 | |
| GSE74703 | PDCD5 | 9141 | 5 | 4 | 27 | |
| GSE74704 | PDCD5 | 9141 | 6 | 3 | 11 | |
| TCGA | PDCD5 | 9141 | 19 | 11 | 66 |
Total number of gains: 137; Total number of losses: 54; Total Number of normals: 297.
Somatic mutations of PDCD5:
Generating mutation plots.
Highly correlated genes for PDCD5:
Showing top 20/1363 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PDCD5 | ZNF584 | 0.79772 | 3 | 0 | 3 |
| PDCD5 | UBQLN4 | 0.793716 | 3 | 0 | 3 |
| PDCD5 | PPP1R16A | 0.783405 | 4 | 0 | 4 |
| PDCD5 | SLC25A29 | 0.773271 | 3 | 0 | 3 |
| PDCD5 | PPP1CA | 0.761056 | 3 | 0 | 3 |
| PDCD5 | CHD7 | 0.751606 | 3 | 0 | 3 |
| PDCD5 | RBM26 | 0.741595 | 3 | 0 | 3 |
| PDCD5 | GPAA1 | 0.740491 | 3 | 0 | 3 |
| PDCD5 | ALG1 | 0.735048 | 3 | 0 | 3 |
| PDCD5 | ALKBH6 | 0.732111 | 5 | 0 | 4 |
| PDCD5 | ATXN2 | 0.72545 | 3 | 0 | 3 |
| PDCD5 | RPS19BP1 | 0.717763 | 4 | 0 | 3 |
| PDCD5 | PLEKHH1 | 0.715814 | 3 | 0 | 3 |
| PDCD5 | MRPL55 | 0.714525 | 5 | 0 | 4 |
| PDCD5 | RNF4 | 0.711524 | 3 | 0 | 3 |
| PDCD5 | RBM39 | 0.710525 | 4 | 0 | 3 |
| PDCD5 | PPP1R37 | 0.709274 | 4 | 0 | 4 |
| PDCD5 | TUBGCP3 | 0.707927 | 3 | 0 | 3 |
| PDCD5 | DYRK2 | 0.707008 | 3 | 0 | 3 |
| PDCD5 | KRTCAP2 | 0.706726 | 5 | 0 | 4 |
For details and further investigation, click here
