| Full name: phosducin like 2 | Alias Symbol: GCPHLP | ||
| Type: protein-coding gene | Cytoband: 4q12 | ||
| Entrez ID: 132954 | HGNC ID: HGNC:29524 | Ensembl Gene: ENSG00000163440 | OMIM ID: 611676 |
| Drug and gene relationship at DGIdb | |||
Expression of PDCL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PDCL2 | 132954 | 237477_at | 0.1603 | 0.6187 | |
| GSE26886 | PDCL2 | 132954 | 237477_at | -0.1264 | 0.1840 | |
| GSE45670 | PDCL2 | 132954 | 237477_at | -0.0991 | 0.0901 | |
| GSE53622 | PDCL2 | 132954 | 23014 | -1.2328 | 0.0000 | |
| GSE53624 | PDCL2 | 132954 | 23014 | -1.7244 | 0.0000 | |
| GSE63941 | PDCL2 | 132954 | 237477_at | 0.0917 | 0.3731 | |
| GSE77861 | PDCL2 | 132954 | 237477_at | -0.0914 | 0.1792 | |
| TCGA | PDCL2 | 132954 | RNAseq | 1.6059 | 0.3210 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by PDCL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PDCL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PDCL2 | 132954 | 3 | 11 | 16 | |
| GSE20123 | PDCL2 | 132954 | 2 | 11 | 17 | |
| GSE43470 | PDCL2 | 132954 | 0 | 14 | 29 | |
| GSE46452 | PDCL2 | 132954 | 1 | 36 | 22 | |
| GSE47630 | PDCL2 | 132954 | 1 | 18 | 21 | |
| GSE54993 | PDCL2 | 132954 | 7 | 0 | 63 | |
| GSE54994 | PDCL2 | 132954 | 2 | 10 | 41 | |
| GSE60625 | PDCL2 | 132954 | 0 | 0 | 11 | |
| GSE74703 | PDCL2 | 132954 | 0 | 12 | 24 | |
| GSE74704 | PDCL2 | 132954 | 1 | 6 | 13 | |
| TCGA | PDCL2 | 132954 | 20 | 27 | 49 |
Total number of gains: 37; Total number of losses: 145; Total Number of normals: 306.
Somatic mutations of PDCL2:
Generating mutation plots.
Highly correlated genes for PDCL2:
Showing top 20/490 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PDCL2 | PHACTR4 | 0.754995 | 3 | 0 | 3 |
| PDCL2 | KLK13 | 0.702694 | 3 | 0 | 3 |
| PDCL2 | SFI1 | 0.69812 | 3 | 0 | 3 |
| PDCL2 | CLCN3 | 0.689738 | 3 | 0 | 3 |
| PDCL2 | ETFDH | 0.687796 | 3 | 0 | 3 |
| PDCL2 | TEC | 0.686003 | 3 | 0 | 3 |
| PDCL2 | NAGK | 0.683929 | 3 | 0 | 3 |
| PDCL2 | ARSF | 0.683502 | 3 | 0 | 3 |
| PDCL2 | BTBD19 | 0.681782 | 3 | 0 | 3 |
| PDCL2 | CLINT1 | 0.68019 | 3 | 0 | 3 |
| PDCL2 | TXN | 0.677212 | 3 | 0 | 3 |
| PDCL2 | KRT83 | 0.676792 | 3 | 0 | 3 |
| PDCL2 | SERPINB4 | 0.676418 | 3 | 0 | 3 |
| PDCL2 | CYP2C18 | 0.674084 | 4 | 0 | 4 |
| PDCL2 | MCEE | 0.671218 | 3 | 0 | 3 |
| PDCL2 | SLC13A4 | 0.67116 | 3 | 0 | 3 |
| PDCL2 | SPATA19 | 0.667542 | 3 | 0 | 3 |
| PDCL2 | ANKRD13A | 0.662921 | 3 | 0 | 3 |
| PDCL2 | CHP1 | 0.66257 | 4 | 0 | 3 |
| PDCL2 | HOPX | 0.661624 | 4 | 0 | 4 |
For details and further investigation, click here
