| Full name: calcineurin like EF-hand protein 1 | Alias Symbol: Sid470p|CHP|SLC9A1BP|p22|p24 | ||
| Type: protein-coding gene | Cytoband: 15q15.1 | ||
| Entrez ID: 11261 | HGNC ID: HGNC:17433 | Ensembl Gene: ENSG00000187446 | OMIM ID: 606988 |
| Drug and gene relationship at DGIdb | |||
Expression of CHP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CHP1 | 11261 | 214665_s_at | -0.6258 | 0.1946 | |
| GSE20347 | CHP1 | 11261 | 214665_s_at | -1.0935 | 0.0000 | |
| GSE23400 | CHP1 | 11261 | 214665_s_at | -0.7083 | 0.0000 | |
| GSE26886 | CHP1 | 11261 | 214665_s_at | -1.2663 | 0.0000 | |
| GSE29001 | CHP1 | 11261 | 214665_s_at | -1.1632 | 0.0001 | |
| GSE38129 | CHP1 | 11261 | 214665_s_at | -0.8154 | 0.0000 | |
| GSE45670 | CHP1 | 11261 | 214665_s_at | -0.5261 | 0.0049 | |
| GSE53622 | CHP1 | 11261 | 65769 | -1.3504 | 0.0000 | |
| GSE53624 | CHP1 | 11261 | 65769 | -1.3957 | 0.0000 | |
| GSE63941 | CHP1 | 11261 | 214665_s_at | -0.1524 | 0.4424 | |
| GSE77861 | CHP1 | 11261 | 214665_s_at | -0.6447 | 0.0129 | |
| SRP007169 | CHP1 | 11261 | RNAseq | -2.4694 | 0.0000 | |
| SRP008496 | CHP1 | 11261 | RNAseq | -2.3475 | 0.0000 | |
| SRP064894 | CHP1 | 11261 | RNAseq | -1.6125 | 0.0000 | |
| SRP133303 | CHP1 | 11261 | RNAseq | -1.0472 | 0.0000 | |
| SRP159526 | CHP1 | 11261 | RNAseq | -1.5038 | 0.0000 | |
| SRP193095 | CHP1 | 11261 | RNAseq | -1.4229 | 0.0000 | |
| SRP219564 | CHP1 | 11261 | RNAseq | -1.4281 | 0.0027 |
Upregulated datasets: 0; Downregulated datasets: 12.
Survival by CHP1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of CHP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CHP1 | 11261 | 3 | 6 | 21 | |
| GSE20123 | CHP1 | 11261 | 3 | 6 | 21 | |
| GSE43470 | CHP1 | 11261 | 4 | 6 | 33 | |
| GSE46452 | CHP1 | 11261 | 3 | 7 | 49 | |
| GSE47630 | CHP1 | 11261 | 8 | 11 | 21 | |
| GSE54993 | CHP1 | 11261 | 4 | 6 | 60 | |
| GSE54994 | CHP1 | 11261 | 5 | 7 | 41 | |
| GSE60625 | CHP1 | 11261 | 4 | 0 | 7 | |
| GSE74703 | CHP1 | 11261 | 4 | 5 | 27 | |
| GSE74704 | CHP1 | 11261 | 2 | 4 | 14 | |
| TCGA | CHP1 | 11261 | 11 | 18 | 67 |
Total number of gains: 51; Total number of losses: 76; Total Number of normals: 361.
Somatic mutations of CHP1:
Generating mutation plots.
Highly correlated genes for CHP1:
Showing top 20/1923 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CHP1 | TCP11L2 | 0.868887 | 4 | 0 | 4 |
| CHP1 | TMOD3 | 0.868618 | 10 | 0 | 10 |
| CHP1 | KRT78 | 0.862139 | 6 | 0 | 6 |
| CHP1 | ABLIM1 | 0.861028 | 10 | 0 | 10 |
| CHP1 | PPL | 0.859607 | 10 | 0 | 10 |
| CHP1 | EVPL | 0.857402 | 10 | 0 | 10 |
| CHP1 | SMAGP | 0.851887 | 10 | 0 | 10 |
| CHP1 | DUOX1 | 0.851607 | 10 | 0 | 10 |
| CHP1 | SPINK7 | 0.847123 | 6 | 0 | 6 |
| CHP1 | SCEL | 0.846633 | 10 | 0 | 10 |
| CHP1 | ENDOU | 0.846134 | 10 | 0 | 10 |
| CHP1 | CLIC3 | 0.846039 | 8 | 0 | 8 |
| CHP1 | PRSS27 | 0.845382 | 6 | 0 | 6 |
| CHP1 | A2ML1 | 0.844268 | 6 | 0 | 6 |
| CHP1 | EPS8L2 | 0.843889 | 10 | 0 | 10 |
| CHP1 | TP53I3 | 0.841957 | 10 | 0 | 10 |
| CHP1 | CYSRT1 | 0.841491 | 6 | 0 | 6 |
| CHP1 | SCNN1B | 0.841428 | 10 | 0 | 10 |
| CHP1 | GDPD3 | 0.841164 | 10 | 0 | 10 |
| CHP1 | SASH1 | 0.839694 | 10 | 0 | 10 |
For details and further investigation, click here
