| Full name: PDZ and LIM domain 4 | Alias Symbol: RIL | ||
| Type: protein-coding gene | Cytoband: 5q31.1 | ||
| Entrez ID: 8572 | HGNC ID: HGNC:16501 | Ensembl Gene: ENSG00000131435 | OMIM ID: 603422 |
Expression of PDLIM4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PDLIM4 | 8572 | 214175_x_at | -0.1886 | 0.8108 | |
| GSE20347 | PDLIM4 | 8572 | 214175_x_at | -0.1690 | 0.5580 | |
| GSE23400 | PDLIM4 | 8572 | 211564_s_at | 0.2027 | 0.1617 | |
| GSE26886 | PDLIM4 | 8572 | 214175_x_at | 0.6502 | 0.0665 | |
| GSE29001 | PDLIM4 | 8572 | 214175_x_at | 0.0662 | 0.9104 | |
| GSE38129 | PDLIM4 | 8572 | 214175_x_at | -0.1389 | 0.5056 | |
| GSE45670 | PDLIM4 | 8572 | 214175_x_at | -0.0382 | 0.9163 | |
| GSE63941 | PDLIM4 | 8572 | 214175_x_at | -1.1804 | 0.2331 | |
| GSE77861 | PDLIM4 | 8572 | 214175_x_at | 0.1925 | 0.6340 | |
| GSE97050 | PDLIM4 | 8572 | A_33_P3237729 | -0.6987 | 0.1495 | |
| SRP007169 | PDLIM4 | 8572 | RNAseq | -0.3256 | 0.5171 | |
| SRP008496 | PDLIM4 | 8572 | RNAseq | -0.2776 | 0.4034 | |
| SRP064894 | PDLIM4 | 8572 | RNAseq | 0.3616 | 0.2632 | |
| SRP133303 | PDLIM4 | 8572 | RNAseq | 0.4508 | 0.1462 | |
| SRP159526 | PDLIM4 | 8572 | RNAseq | 0.5681 | 0.0880 | |
| SRP193095 | PDLIM4 | 8572 | RNAseq | 0.3336 | 0.2413 | |
| SRP219564 | PDLIM4 | 8572 | RNAseq | -0.1574 | 0.7430 | |
| TCGA | PDLIM4 | 8572 | RNAseq | 0.2164 | 0.0458 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PDLIM4 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of PDLIM4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PDLIM4 | 8572 | 1 | 11 | 18 | |
| GSE20123 | PDLIM4 | 8572 | 2 | 11 | 17 | |
| GSE43470 | PDLIM4 | 8572 | 2 | 9 | 32 | |
| GSE46452 | PDLIM4 | 8572 | 0 | 27 | 32 | |
| GSE47630 | PDLIM4 | 8572 | 0 | 21 | 19 | |
| GSE54993 | PDLIM4 | 8572 | 9 | 1 | 60 | |
| GSE54994 | PDLIM4 | 8572 | 2 | 14 | 37 | |
| GSE60625 | PDLIM4 | 8572 | 0 | 0 | 11 | |
| GSE74703 | PDLIM4 | 8572 | 2 | 6 | 28 | |
| GSE74704 | PDLIM4 | 8572 | 1 | 5 | 14 | |
| TCGA | PDLIM4 | 8572 | 3 | 39 | 54 |
Total number of gains: 22; Total number of losses: 144; Total Number of normals: 322.
Somatic mutations of PDLIM4:
Generating mutation plots.
Highly correlated genes for PDLIM4:
Showing top 20/66 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PDLIM4 | RNF122 | 0.699965 | 3 | 0 | 3 |
| PDLIM4 | OBSCN | 0.694138 | 4 | 0 | 3 |
| PDLIM4 | CRTAP | 0.680561 | 3 | 0 | 3 |
| PDLIM4 | TMEM64 | 0.659258 | 4 | 0 | 3 |
| PDLIM4 | PNRC1 | 0.645065 | 3 | 0 | 3 |
| PDLIM4 | AGAP2 | 0.643623 | 3 | 0 | 3 |
| PDLIM4 | PRDM8 | 0.6381 | 3 | 0 | 3 |
| PDLIM4 | CACNA1H | 0.637296 | 4 | 0 | 4 |
| PDLIM4 | MYL3 | 0.634141 | 3 | 0 | 3 |
| PDLIM4 | NOVA2 | 0.631496 | 3 | 0 | 3 |
| PDLIM4 | PFKP | 0.628831 | 4 | 0 | 3 |
| PDLIM4 | SOD3 | 0.619433 | 3 | 0 | 3 |
| PDLIM4 | PCBP4 | 0.601916 | 3 | 0 | 3 |
| PDLIM4 | PHPT1 | 0.600828 | 4 | 0 | 4 |
| PDLIM4 | TNPO1 | 0.597409 | 4 | 0 | 4 |
| PDLIM4 | POU6F1 | 0.5965 | 4 | 0 | 3 |
| PDLIM4 | TSPYL2 | 0.594523 | 4 | 0 | 3 |
| PDLIM4 | NPFFR1 | 0.591203 | 3 | 0 | 3 |
| PDLIM4 | MAGEH1 | 0.583785 | 3 | 0 | 3 |
| PDLIM4 | TGFB1I1 | 0.582164 | 4 | 0 | 4 |
For details and further investigation, click here
