| Full name: erythrocyte membrane protein band 4.1 like 4A | Alias Symbol: NBL4 | ||
| Type: protein-coding gene | Cytoband: 5q22.1-q22.2 | ||
| Entrez ID: 64097 | HGNC ID: HGNC:13278 | Ensembl Gene: ENSG00000129595 | OMIM ID: 612141 |
| Drug and gene relationship at DGIdb | |||
Expression of EPB41L4A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EPB41L4A | 64097 | 228256_s_at | -1.6569 | 0.0702 | |
| GSE20347 | EPB41L4A | 64097 | 220119_at | -0.9487 | 0.0000 | |
| GSE23400 | EPB41L4A | 64097 | 220119_at | -0.6372 | 0.0000 | |
| GSE26886 | EPB41L4A | 64097 | 228256_s_at | -2.1960 | 0.0001 | |
| GSE29001 | EPB41L4A | 64097 | 220119_at | -1.1629 | 0.0000 | |
| GSE38129 | EPB41L4A | 64097 | 220119_at | -0.8976 | 0.0000 | |
| GSE45670 | EPB41L4A | 64097 | 228256_s_at | -1.4341 | 0.0007 | |
| GSE63941 | EPB41L4A | 64097 | 228256_s_at | 3.1832 | 0.0065 | |
| GSE77861 | EPB41L4A | 64097 | 228256_s_at | -2.0758 | 0.0003 | |
| GSE97050 | EPB41L4A | 64097 | A_24_P257579 | -0.4639 | 0.2156 | |
| SRP007169 | EPB41L4A | 64097 | RNAseq | -2.4099 | 0.0000 | |
| SRP008496 | EPB41L4A | 64097 | RNAseq | -2.5544 | 0.0000 | |
| SRP064894 | EPB41L4A | 64097 | RNAseq | -1.9520 | 0.0000 | |
| SRP133303 | EPB41L4A | 64097 | RNAseq | -1.4137 | 0.0000 | |
| SRP159526 | EPB41L4A | 64097 | RNAseq | -2.1990 | 0.0000 | |
| SRP193095 | EPB41L4A | 64097 | RNAseq | -1.5421 | 0.0000 | |
| SRP219564 | EPB41L4A | 64097 | RNAseq | -1.3565 | 0.0159 | |
| TCGA | EPB41L4A | 64097 | RNAseq | -0.6471 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 11.
Survival by EPB41L4A expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of EPB41L4A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EPB41L4A | 64097 | 1 | 13 | 16 | |
| GSE20123 | EPB41L4A | 64097 | 1 | 13 | 16 | |
| GSE43470 | EPB41L4A | 64097 | 3 | 8 | 32 | |
| GSE46452 | EPB41L4A | 64097 | 0 | 28 | 31 | |
| GSE47630 | EPB41L4A | 64097 | 0 | 21 | 19 | |
| GSE54993 | EPB41L4A | 64097 | 9 | 1 | 60 | |
| GSE54994 | EPB41L4A | 64097 | 1 | 17 | 35 | |
| GSE60625 | EPB41L4A | 64097 | 0 | 0 | 11 | |
| GSE74703 | EPB41L4A | 64097 | 2 | 6 | 28 | |
| GSE74704 | EPB41L4A | 64097 | 1 | 7 | 12 | |
| TCGA | EPB41L4A | 64097 | 3 | 41 | 52 |
Total number of gains: 21; Total number of losses: 155; Total Number of normals: 312.
Somatic mutations of EPB41L4A:
Generating mutation plots.
Highly correlated genes for EPB41L4A:
Showing top 20/1358 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EPB41L4A | GDPD3 | 0.84474 | 9 | 0 | 9 |
| EPB41L4A | UBL3 | 0.843682 | 9 | 0 | 9 |
| EPB41L4A | SH3BGRL2 | 0.840811 | 5 | 0 | 5 |
| EPB41L4A | GYS2 | 0.834114 | 8 | 0 | 8 |
| EPB41L4A | ACPP | 0.833438 | 9 | 0 | 9 |
| EPB41L4A | ENDOU | 0.832814 | 9 | 0 | 9 |
| EPB41L4A | KRT78 | 0.831004 | 5 | 0 | 5 |
| EPB41L4A | SLC35C1 | 0.823933 | 8 | 0 | 8 |
| EPB41L4A | SAMD5 | 0.821013 | 5 | 0 | 5 |
| EPB41L4A | CLIC3 | 0.817272 | 9 | 0 | 9 |
| EPB41L4A | CRISP3 | 0.816906 | 9 | 0 | 9 |
| EPB41L4A | EHD3 | 0.812983 | 9 | 0 | 9 |
| EPB41L4A | SLC37A1 | 0.811051 | 8 | 0 | 8 |
| EPB41L4A | SPAG17 | 0.807719 | 5 | 0 | 5 |
| EPB41L4A | BNIPL | 0.805948 | 5 | 0 | 5 |
| EPB41L4A | EPS8L2 | 0.804597 | 9 | 0 | 8 |
| EPB41L4A | PADI1 | 0.804553 | 9 | 0 | 9 |
| EPB41L4A | EPB41L3 | 0.803113 | 8 | 0 | 8 |
| EPB41L4A | CYSRT1 | 0.802116 | 4 | 0 | 4 |
| EPB41L4A | SNX24 | 0.800795 | 9 | 0 | 9 |
For details and further investigation, click here
