BCOR

 

Full name: BCL6 corepressor Alias Symbol: FLJ20285|KIAA1575
Type: protein-coding gene Cytoband: Xp11.4
Entrez ID: 54880 HGNC ID: HGNC:20893 Ensembl Gene: ENSG00000183337 OMIM ID: 300485
Drug and gene relationship at DGIdb
Screen Evidence:
  • This gene has been idenfitied as a common driver in this paper.
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of BCOR:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 BCOR 54880 223566_s_at -0.3450 0.4957
GSE20347 BCOR 54880 219433_at -0.6168 0.0000
GSE23400 BCOR 54880 219433_at -0.2962 0.0000
GSE26886 BCOR 54880 219433_at -0.9310 0.0028
GSE29001 BCOR 54880 219433_at -0.9067 0.0035
GSE38129 BCOR 54880 219433_at -0.6114 0.0000
GSE45670 BCOR 54880 219433_at -0.3640 0.1421
GSE53622 BCOR 54880 6585 -0.6950 0.0000
GSE53624 BCOR 54880 6585 -1.2898 0.0000
GSE63941 BCOR 54880 223566_s_at 0.6283 0.1106
GSE77861 BCOR 54880 223915_at -0.2610 0.3602
GSE97050 BCOR 54880 A_23_P159741 -0.7516 0.2637
SRP007169 BCOR 54880 RNAseq -2.0348 0.0000
SRP008496 BCOR 54880 RNAseq -1.5326 0.0000
SRP064894 BCOR 54880 RNAseq -1.0933 0.0002
SRP133303 BCOR 54880 RNAseq -0.5899 0.0000
SRP159526 BCOR 54880 RNAseq -0.5740 0.0034
SRP193095 BCOR 54880 RNAseq -0.6144 0.0000
SRP219564 BCOR 54880 RNAseq -0.5923 0.1678
TCGA BCOR 54880 RNAseq -0.1391 0.0054

Upregulated datasets: 0; Downregulated datasets: 4.  


 

Survival by BCOR expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of BCOR:

 

No record found for this gene.


 

Somatic mutations of BCOR:

 

Generating mutation plots.

 

Highly correlated genes for BCOR:

 

Showing top 20/929 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
BCORPDZD20.727113909
BCORTCP11L20.719514505
BCORRASSF50.702226606
BCORBLNK0.69943411011
BCORFAM214A0.697602606
BCORRANBP90.69408212010
BCORPHACTR40.69352512011
BCORCXCR20.6931211009
BCORCHP10.69247110010
BCORSPINK70.688373606
BCORCCNG20.68781612011
BCORAAMP0.687604403
BCORSLC46A20.684075504
BCORRMND5B0.68379610010
BCORCPEB30.681566909
BCORKLHDC7A0.681229303
BCORSPATA180.67947505
BCORSCNN1B0.6784710010
BCORTTC90.67370811010
BCORLNX10.672889605

For details and further investigation, click here