| Full name: peroxisomal biogenesis factor 19 | Alias Symbol: HK33|D1S2223E|PMP1|PMPI|PXMP1 | ||
| Type: protein-coding gene | Cytoband: 1q23.2 | ||
| Entrez ID: 5824 | HGNC ID: HGNC:9713 | Ensembl Gene: ENSG00000162735 | OMIM ID: 600279 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PEX19:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PEX19 | 5824 | 201706_s_at | -0.2071 | 0.4758 | |
| GSE20347 | PEX19 | 5824 | 201706_s_at | -0.1871 | 0.1815 | |
| GSE23400 | PEX19 | 5824 | 201707_at | -0.0684 | 0.1423 | |
| GSE26886 | PEX19 | 5824 | 201706_s_at | -0.7118 | 0.0040 | |
| GSE29001 | PEX19 | 5824 | 201707_at | -0.1054 | 0.7479 | |
| GSE38129 | PEX19 | 5824 | 201706_s_at | -0.2547 | 0.0316 | |
| GSE45670 | PEX19 | 5824 | 201707_at | -0.3564 | 0.0026 | |
| GSE53622 | PEX19 | 5824 | 124190 | -0.2687 | 0.0004 | |
| GSE53624 | PEX19 | 5824 | 124190 | -0.1622 | 0.0711 | |
| GSE63941 | PEX19 | 5824 | 201707_at | -0.9733 | 0.0151 | |
| GSE77861 | PEX19 | 5824 | 201706_s_at | -0.0472 | 0.8376 | |
| GSE97050 | PEX19 | 5824 | A_24_P19752 | -0.2272 | 0.3917 | |
| SRP007169 | PEX19 | 5824 | RNAseq | -0.7977 | 0.0113 | |
| SRP008496 | PEX19 | 5824 | RNAseq | -0.4705 | 0.0452 | |
| SRP064894 | PEX19 | 5824 | RNAseq | -0.3239 | 0.0020 | |
| SRP133303 | PEX19 | 5824 | RNAseq | -0.0351 | 0.7978 | |
| SRP159526 | PEX19 | 5824 | RNAseq | 0.2955 | 0.1397 | |
| SRP193095 | PEX19 | 5824 | RNAseq | -0.1586 | 0.0596 | |
| SRP219564 | PEX19 | 5824 | RNAseq | -0.4259 | 0.1939 | |
| TCGA | PEX19 | 5824 | RNAseq | -0.1494 | 0.0008 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PEX19 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PEX19:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PEX19 | 5824 | 10 | 0 | 20 | |
| GSE20123 | PEX19 | 5824 | 10 | 0 | 20 | |
| GSE43470 | PEX19 | 5824 | 7 | 2 | 34 | |
| GSE46452 | PEX19 | 5824 | 2 | 1 | 56 | |
| GSE47630 | PEX19 | 5824 | 15 | 0 | 25 | |
| GSE54993 | PEX19 | 5824 | 0 | 5 | 65 | |
| GSE54994 | PEX19 | 5824 | 16 | 0 | 37 | |
| GSE60625 | PEX19 | 5824 | 0 | 0 | 11 | |
| GSE74703 | PEX19 | 5824 | 7 | 2 | 27 | |
| GSE74704 | PEX19 | 5824 | 4 | 0 | 16 | |
| TCGA | PEX19 | 5824 | 44 | 3 | 49 |
Total number of gains: 115; Total number of losses: 13; Total Number of normals: 360.
Somatic mutations of PEX19:
Generating mutation plots.
Highly correlated genes for PEX19:
Showing top 20/819 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PEX19 | FYTTD1 | 0.782353 | 3 | 0 | 3 |
| PEX19 | TRAF6 | 0.770315 | 3 | 0 | 3 |
| PEX19 | FPGT | 0.764431 | 3 | 0 | 3 |
| PEX19 | RIOK2 | 0.760208 | 3 | 0 | 3 |
| PEX19 | AFF3 | 0.735255 | 3 | 0 | 3 |
| PEX19 | ZNF570 | 0.735236 | 3 | 0 | 3 |
| PEX19 | VTI1B | 0.729875 | 3 | 0 | 3 |
| PEX19 | SNX19 | 0.727395 | 4 | 0 | 4 |
| PEX19 | ZNF256 | 0.723853 | 3 | 0 | 3 |
| PEX19 | PPP4R1 | 0.721231 | 3 | 0 | 3 |
| PEX19 | PLEKHM3 | 0.720358 | 3 | 0 | 3 |
| PEX19 | TBCC | 0.712683 | 4 | 0 | 4 |
| PEX19 | FILIP1 | 0.709996 | 3 | 0 | 3 |
| PEX19 | RABL3 | 0.708378 | 3 | 0 | 3 |
| PEX19 | KLF4 | 0.705131 | 3 | 0 | 3 |
| PEX19 | PITPNM3 | 0.704175 | 3 | 0 | 3 |
| PEX19 | FAM76A | 0.704015 | 3 | 0 | 3 |
| PEX19 | RSRC2 | 0.703959 | 4 | 0 | 3 |
| PEX19 | TBC1D19 | 0.698532 | 4 | 0 | 3 |
| PEX19 | SPOPL | 0.697603 | 4 | 0 | 4 |
For details and further investigation, click here
