| Full name: vesicle transport through interaction with t-SNAREs 1B | Alias Symbol: VTI2 | ||
| Type: protein-coding gene | Cytoband: 14q24.1 | ||
| Entrez ID: 10490 | HGNC ID: HGNC:17793 | Ensembl Gene: ENSG00000100568 | OMIM ID: 603207 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of VTI1B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VTI1B | 10490 | 209452_s_at | -0.1495 | 0.6457 | |
| GSE20347 | VTI1B | 10490 | 209452_s_at | -0.3959 | 0.0259 | |
| GSE23400 | VTI1B | 10490 | 209452_s_at | 0.0012 | 0.9876 | |
| GSE26886 | VTI1B | 10490 | 209452_s_at | -0.0287 | 0.9254 | |
| GSE29001 | VTI1B | 10490 | 209452_s_at | -0.4142 | 0.2510 | |
| GSE38129 | VTI1B | 10490 | 209452_s_at | -0.3672 | 0.0039 | |
| GSE45670 | VTI1B | 10490 | 209452_s_at | -0.0603 | 0.6182 | |
| GSE63941 | VTI1B | 10490 | 209452_s_at | -0.0257 | 0.9520 | |
| GSE77861 | VTI1B | 10490 | 209452_s_at | -0.3116 | 0.5269 | |
| GSE97050 | VTI1B | 10490 | A_23_P14284 | -0.1176 | 0.6865 | |
| SRP007169 | VTI1B | 10490 | RNAseq | -1.0568 | 0.0015 | |
| SRP008496 | VTI1B | 10490 | RNAseq | -0.8179 | 0.0008 | |
| SRP064894 | VTI1B | 10490 | RNAseq | -0.2458 | 0.1270 | |
| SRP133303 | VTI1B | 10490 | RNAseq | -0.0840 | 0.6034 | |
| SRP159526 | VTI1B | 10490 | RNAseq | -0.6024 | 0.0218 | |
| SRP193095 | VTI1B | 10490 | RNAseq | -0.4510 | 0.0000 | |
| SRP219564 | VTI1B | 10490 | RNAseq | -0.2778 | 0.3495 | |
| TCGA | VTI1B | 10490 | RNAseq | -0.0759 | 0.1362 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by VTI1B expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of VTI1B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VTI1B | 10490 | 7 | 2 | 21 | |
| GSE20123 | VTI1B | 10490 | 7 | 2 | 21 | |
| GSE43470 | VTI1B | 10490 | 8 | 2 | 33 | |
| GSE46452 | VTI1B | 10490 | 16 | 3 | 40 | |
| GSE47630 | VTI1B | 10490 | 11 | 9 | 20 | |
| GSE54993 | VTI1B | 10490 | 3 | 9 | 58 | |
| GSE54994 | VTI1B | 10490 | 18 | 5 | 30 | |
| GSE60625 | VTI1B | 10490 | 0 | 2 | 9 | |
| GSE74703 | VTI1B | 10490 | 7 | 2 | 27 | |
| GSE74704 | VTI1B | 10490 | 3 | 2 | 15 | |
| TCGA | VTI1B | 10490 | 33 | 14 | 49 |
Total number of gains: 113; Total number of losses: 52; Total Number of normals: 323.
Somatic mutations of VTI1B:
Generating mutation plots.
Highly correlated genes for VTI1B:
Showing top 20/379 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VTI1B | RPS14 | 0.820805 | 3 | 0 | 3 |
| VTI1B | UBR3 | 0.820026 | 3 | 0 | 3 |
| VTI1B | MED8 | 0.801026 | 3 | 0 | 3 |
| VTI1B | RAB22A | 0.779452 | 3 | 0 | 3 |
| VTI1B | TANC1 | 0.772496 | 3 | 0 | 3 |
| VTI1B | ALDH7A1 | 0.767719 | 3 | 0 | 3 |
| VTI1B | RPL18 | 0.766096 | 3 | 0 | 3 |
| VTI1B | VPS28 | 0.749234 | 3 | 0 | 3 |
| VTI1B | PITPNC1 | 0.73597 | 3 | 0 | 3 |
| VTI1B | PEX19 | 0.729875 | 3 | 0 | 3 |
| VTI1B | CTR9 | 0.726556 | 3 | 0 | 3 |
| VTI1B | ATG3 | 0.723509 | 3 | 0 | 3 |
| VTI1B | CALY | 0.710124 | 3 | 0 | 3 |
| VTI1B | AK4 | 0.707317 | 5 | 0 | 4 |
| VTI1B | METAP2 | 0.707261 | 3 | 0 | 3 |
| VTI1B | GTF3A | 0.70436 | 3 | 0 | 3 |
| VTI1B | LMAN2 | 0.703762 | 3 | 0 | 3 |
| VTI1B | TRIM23 | 0.703049 | 4 | 0 | 3 |
| VTI1B | NDUFA10 | 0.698527 | 4 | 0 | 4 |
| VTI1B | GPBP1 | 0.694109 | 3 | 0 | 3 |
For details and further investigation, click here
