| Full name: DNA polymerase delta interacting protein 2 | Alias Symbol: PDIP38|DKFZP586F1524 | ||
| Type: protein-coding gene | Cytoband: 17q11.2 | ||
| Entrez ID: 26073 | HGNC ID: HGNC:23781 | Ensembl Gene: ENSG00000004142 | OMIM ID: 611519 |
| Drug and gene relationship at DGIdb | |||
Expression of POLDIP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | POLDIP2 | 26073 | 222425_s_at | 0.2192 | 0.4111 | |
| GSE20347 | POLDIP2 | 26073 | 217806_s_at | -0.2363 | 0.0591 | |
| GSE23400 | POLDIP2 | 26073 | 217806_s_at | -0.1435 | 0.0036 | |
| GSE26886 | POLDIP2 | 26073 | 217806_s_at | -0.0699 | 0.6950 | |
| GSE29001 | POLDIP2 | 26073 | 217806_s_at | -0.2502 | 0.1540 | |
| GSE38129 | POLDIP2 | 26073 | 217806_s_at | -0.0484 | 0.7271 | |
| GSE45670 | POLDIP2 | 26073 | 217806_s_at | 0.1781 | 0.2517 | |
| GSE53622 | POLDIP2 | 26073 | 93270 | -0.0185 | 0.7903 | |
| GSE53624 | POLDIP2 | 26073 | 93270 | -0.0045 | 0.9514 | |
| GSE63941 | POLDIP2 | 26073 | 222425_s_at | 1.1185 | 0.0014 | |
| GSE77861 | POLDIP2 | 26073 | 217806_s_at | 0.1179 | 0.6722 | |
| GSE97050 | POLDIP2 | 26073 | A_24_P142442 | 0.0322 | 0.8933 | |
| SRP007169 | POLDIP2 | 26073 | RNAseq | -0.5500 | 0.0685 | |
| SRP008496 | POLDIP2 | 26073 | RNAseq | -0.5121 | 0.0091 | |
| SRP064894 | POLDIP2 | 26073 | RNAseq | -0.0413 | 0.8232 | |
| SRP133303 | POLDIP2 | 26073 | RNAseq | 0.0374 | 0.7910 | |
| SRP159526 | POLDIP2 | 26073 | RNAseq | 0.1725 | 0.4206 | |
| SRP193095 | POLDIP2 | 26073 | RNAseq | 0.0172 | 0.8855 | |
| SRP219564 | POLDIP2 | 26073 | RNAseq | -0.0637 | 0.8259 | |
| TCGA | POLDIP2 | 26073 | RNAseq | 0.0129 | 0.7683 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by POLDIP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of POLDIP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | POLDIP2 | 26073 | 9 | 1 | 20 | |
| GSE20123 | POLDIP2 | 26073 | 9 | 1 | 20 | |
| GSE43470 | POLDIP2 | 26073 | 0 | 1 | 42 | |
| GSE46452 | POLDIP2 | 26073 | 33 | 1 | 25 | |
| GSE47630 | POLDIP2 | 26073 | 7 | 1 | 32 | |
| GSE54993 | POLDIP2 | 26073 | 2 | 3 | 65 | |
| GSE54994 | POLDIP2 | 26073 | 7 | 6 | 40 | |
| GSE60625 | POLDIP2 | 26073 | 4 | 0 | 7 | |
| GSE74703 | POLDIP2 | 26073 | 0 | 1 | 35 | |
| GSE74704 | POLDIP2 | 26073 | 7 | 1 | 12 | |
| TCGA | POLDIP2 | 26073 | 21 | 10 | 65 |
Total number of gains: 99; Total number of losses: 26; Total Number of normals: 363.
Somatic mutations of POLDIP2:
Generating mutation plots.
Highly correlated genes for POLDIP2:
Showing top 20/454 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| POLDIP2 | CDYL | 0.798971 | 3 | 0 | 3 |
| POLDIP2 | ATP6V0B | 0.77629 | 3 | 0 | 3 |
| POLDIP2 | MTCH2 | 0.769793 | 4 | 0 | 4 |
| POLDIP2 | XPO6 | 0.766971 | 3 | 0 | 3 |
| POLDIP2 | DDOST | 0.764902 | 3 | 0 | 3 |
| POLDIP2 | CMTM4 | 0.756393 | 3 | 0 | 3 |
| POLDIP2 | KLHDC3 | 0.749438 | 3 | 0 | 3 |
| POLDIP2 | KDM5B | 0.738725 | 3 | 0 | 3 |
| POLDIP2 | PDZD11 | 0.737188 | 3 | 0 | 3 |
| POLDIP2 | GPR160 | 0.731828 | 3 | 0 | 3 |
| POLDIP2 | ERI3 | 0.729662 | 3 | 0 | 3 |
| POLDIP2 | EEFSEC | 0.728597 | 3 | 0 | 3 |
| POLDIP2 | C20orf27 | 0.719249 | 3 | 0 | 3 |
| POLDIP2 | MRPL27 | 0.718849 | 3 | 0 | 3 |
| POLDIP2 | MRPL38 | 0.718122 | 4 | 0 | 3 |
| POLDIP2 | SDHAF2 | 0.711388 | 4 | 0 | 3 |
| POLDIP2 | LMBR1 | 0.711197 | 3 | 0 | 3 |
| POLDIP2 | ERCC6 | 0.70491 | 3 | 0 | 3 |
| POLDIP2 | PPP6R3 | 0.704565 | 3 | 0 | 3 |
| POLDIP2 | RNPS1 | 0.704061 | 3 | 0 | 3 |
For details and further investigation, click here
