PEX5

 

Full name: peroxisomal biogenesis factor 5 Alias Symbol: PTS1R
Type: protein-coding gene Cytoband: 12p13.31
Entrez ID: 5830 HGNC ID: HGNC:9719 Ensembl Gene: ENSG00000139197 OMIM ID: 600414
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of PEX5:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PEX5 5830 203244_at 0.7089 0.0702
GSE20347 PEX5 5830 203244_at 0.5749 0.0001
GSE23400 PEX5 5830 203244_at 0.4307 0.0000
GSE26886 PEX5 5830 203244_at 0.5842 0.0580
GSE29001 PEX5 5830 203244_at 0.7291 0.0534
GSE38129 PEX5 5830 203244_at 0.3546 0.0148
GSE45670 PEX5 5830 203244_at 0.2405 0.3012
GSE53622 PEX5 5830 50408 0.2592 0.0008
GSE53624 PEX5 5830 50408 0.1881 0.0348
GSE63941 PEX5 5830 203244_at 0.0125 0.9759
GSE77861 PEX5 5830 203244_at 0.5689 0.0526
GSE97050 PEX5 5830 A_24_P372932 0.0937 0.7831
SRP007169 PEX5 5830 RNAseq 0.4927 0.2690
SRP008496 PEX5 5830 RNAseq 0.2144 0.4615
SRP064894 PEX5 5830 RNAseq 0.1098 0.3844
SRP133303 PEX5 5830 RNAseq 0.3971 0.0435
SRP159526 PEX5 5830 RNAseq 0.4293 0.0326
SRP193095 PEX5 5830 RNAseq 0.3156 0.0005
SRP219564 PEX5 5830 RNAseq 0.2177 0.5204
TCGA PEX5 5830 RNAseq 0.0802 0.1245

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by PEX5 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of PEX5:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PEX5 5830 7 3 20
GSE20123 PEX5 5830 7 3 20
GSE43470 PEX5 5830 8 3 32
GSE46452 PEX5 5830 10 1 48
GSE47630 PEX5 5830 12 2 26
GSE54993 PEX5 5830 1 10 59
GSE54994 PEX5 5830 10 2 41
GSE60625 PEX5 5830 0 1 10
GSE74703 PEX5 5830 7 2 27
GSE74704 PEX5 5830 4 2 14
TCGA PEX5 5830 40 6 50

Total number of gains: 106; Total number of losses: 35; Total Number of normals: 347.  

 

Somatic mutations of PEX5:

 

Generating mutation plots.

 

Highly correlated genes for PEX5:

 

Showing top 20/426 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PEX5FBXO410.692721303
PEX5TAS2R310.678187303
PEX5GMNN0.674197404
PEX5SAPCD20.668175303
PEX5KRTAP4-10.6535505
PEX5SERPINH10.645205808
PEX5TOMM340.642608503
PEX5DHX90.639267807
PEX5PXYLP10.636722403
PEX5NOP20.6359651007
PEX5B4GALT30.633453404
PEX5COLGALT10.627153706
PEX5HAUS80.626864404
PEX5RAD51AP10.623044806
PEX5PDIA40.622787605
PEX5PHB20.621349906
PEX5E2F60.619825705
PEX5FOXO60.618394303
PEX5TAS2R300.618325303
PEX5ANKRD390.618258403

For details and further investigation, click here