| Full name: suppressor APC domain containing 2 | Alias Symbol: p42.3 | ||
| Type: protein-coding gene | Cytoband: 9q34.3 | ||
| Entrez ID: 89958 | HGNC ID: HGNC:28055 | Ensembl Gene: ENSG00000186193 | OMIM ID: 612057 |
| Drug and gene relationship at DGIdb | |||
Expression of SAPCD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SAPCD2 | 89958 | 225777_at | 0.9623 | 0.0517 | |
| GSE26886 | SAPCD2 | 89958 | 225777_at | 0.2810 | 0.1023 | |
| GSE45670 | SAPCD2 | 89958 | 225777_at | 0.7412 | 0.0050 | |
| GSE53622 | SAPCD2 | 89958 | 151360 | 1.4345 | 0.0000 | |
| GSE53624 | SAPCD2 | 89958 | 151360 | 1.4561 | 0.0000 | |
| GSE63941 | SAPCD2 | 89958 | 225777_at | 1.6823 | 0.0021 | |
| GSE77861 | SAPCD2 | 89958 | 225777_at | 0.6632 | 0.0038 | |
| SRP007169 | SAPCD2 | 89958 | RNAseq | 1.7433 | 0.0005 | |
| SRP008496 | SAPCD2 | 89958 | RNAseq | 1.4278 | 0.0003 | |
| SRP064894 | SAPCD2 | 89958 | RNAseq | 0.9225 | 0.0096 | |
| SRP133303 | SAPCD2 | 89958 | RNAseq | 1.1516 | 0.0032 | |
| SRP159526 | SAPCD2 | 89958 | RNAseq | 1.7596 | 0.0000 | |
| SRP193095 | SAPCD2 | 89958 | RNAseq | 1.1624 | 0.0000 | |
| SRP219564 | SAPCD2 | 89958 | RNAseq | 1.5691 | 0.0227 |
Upregulated datasets: 9; Downregulated datasets: 0.
Survival by SAPCD2 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of SAPCD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SAPCD2 | 89958 | 5 | 7 | 18 | |
| GSE20123 | SAPCD2 | 89958 | 5 | 7 | 18 | |
| GSE43470 | SAPCD2 | 89958 | 3 | 7 | 33 | |
| GSE46452 | SAPCD2 | 89958 | 6 | 13 | 40 | |
| GSE47630 | SAPCD2 | 89958 | 6 | 15 | 19 | |
| GSE54993 | SAPCD2 | 89958 | 3 | 3 | 64 | |
| GSE54994 | SAPCD2 | 89958 | 12 | 8 | 33 | |
| GSE60625 | SAPCD2 | 89958 | 0 | 0 | 11 | |
| GSE74703 | SAPCD2 | 89958 | 3 | 5 | 28 | |
| GSE74704 | SAPCD2 | 89958 | 3 | 5 | 12 | |
| TCGA | SAPCD2 | 89958 | 29 | 23 | 44 |
Total number of gains: 75; Total number of losses: 93; Total Number of normals: 320.
Somatic mutations of SAPCD2:
Generating mutation plots.
Highly correlated genes for SAPCD2:
Showing top 20/1211 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SAPCD2 | NCAPH | 0.798182 | 4 | 0 | 4 |
| SAPCD2 | CENPN | 0.774422 | 6 | 0 | 6 |
| SAPCD2 | CEP55 | 0.766311 | 6 | 0 | 6 |
| SAPCD2 | CHAF1A | 0.76199 | 6 | 0 | 6 |
| SAPCD2 | DSCC1 | 0.759702 | 4 | 0 | 4 |
| SAPCD2 | CENPM | 0.759596 | 6 | 0 | 6 |
| SAPCD2 | BUB1 | 0.758174 | 6 | 0 | 6 |
| SAPCD2 | CDCA3 | 0.757715 | 6 | 0 | 6 |
| SAPCD2 | CENPA | 0.755003 | 6 | 0 | 6 |
| SAPCD2 | BUB1B | 0.753825 | 4 | 0 | 4 |
| SAPCD2 | ECT2 | 0.753653 | 6 | 0 | 6 |
| SAPCD2 | CENPF | 0.752263 | 6 | 0 | 6 |
| SAPCD2 | CDCA2 | 0.749165 | 4 | 0 | 4 |
| SAPCD2 | CCNB2 | 0.748642 | 5 | 0 | 5 |
| SAPCD2 | FOXM1 | 0.74804 | 6 | 0 | 6 |
| SAPCD2 | RAD51AP1 | 0.74799 | 6 | 0 | 6 |
| SAPCD2 | NUF2 | 0.74782 | 6 | 0 | 6 |
| SAPCD2 | DDX39A | 0.746305 | 7 | 0 | 7 |
| SAPCD2 | UBE2C | 0.744747 | 6 | 0 | 6 |
| SAPCD2 | LMNB2 | 0.744138 | 6 | 0 | 5 |
For details and further investigation, click here
