| Full name: phosphoglucomutase 3 | Alias Symbol: AGM1|DKFZP434B187|PAGM | ||
| Type: protein-coding gene | Cytoband: 6q14.1 | ||
| Entrez ID: 5238 | HGNC ID: HGNC:8907 | Ensembl Gene: ENSG00000013375 | OMIM ID: 172100 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PGM3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PGM3 | 5238 | 210041_s_at | -0.4167 | 0.5887 | |
| GSE20347 | PGM3 | 5238 | 221788_at | 0.0791 | 0.6650 | |
| GSE23400 | PGM3 | 5238 | 221788_at | 0.0772 | 0.1830 | |
| GSE26886 | PGM3 | 5238 | 210041_s_at | -0.8835 | 0.0170 | |
| GSE29001 | PGM3 | 5238 | 210041_s_at | 0.1796 | 0.6498 | |
| GSE38129 | PGM3 | 5238 | 221788_at | 0.2296 | 0.1057 | |
| GSE45670 | PGM3 | 5238 | 210041_s_at | 0.4105 | 0.0348 | |
| GSE53622 | PGM3 | 5238 | 105561 | 0.4183 | 0.0000 | |
| GSE53624 | PGM3 | 5238 | 105561 | 0.3660 | 0.0000 | |
| GSE63941 | PGM3 | 5238 | 210041_s_at | -1.3315 | 0.0073 | |
| GSE77861 | PGM3 | 5238 | 210041_s_at | -0.0463 | 0.8752 | |
| GSE97050 | PGM3 | 5238 | A_23_P19592 | 0.8401 | 0.1698 | |
| SRP007169 | PGM3 | 5238 | RNAseq | 0.2784 | 0.4645 | |
| SRP008496 | PGM3 | 5238 | RNAseq | 0.0794 | 0.7331 | |
| SRP064894 | PGM3 | 5238 | RNAseq | 0.3895 | 0.1063 | |
| SRP133303 | PGM3 | 5238 | RNAseq | 0.7039 | 0.0124 | |
| SRP159526 | PGM3 | 5238 | RNAseq | 0.0683 | 0.7341 | |
| SRP193095 | PGM3 | 5238 | RNAseq | 0.0428 | 0.8091 | |
| SRP219564 | PGM3 | 5238 | RNAseq | 0.3020 | 0.5402 | |
| TCGA | PGM3 | 5238 | RNAseq | -0.0645 | 0.2947 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PGM3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PGM3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PGM3 | 5238 | 1 | 4 | 25 | |
| GSE20123 | PGM3 | 5238 | 1 | 3 | 26 | |
| GSE43470 | PGM3 | 5238 | 2 | 1 | 40 | |
| GSE46452 | PGM3 | 5238 | 2 | 11 | 46 | |
| GSE47630 | PGM3 | 5238 | 8 | 6 | 26 | |
| GSE54993 | PGM3 | 5238 | 3 | 2 | 65 | |
| GSE54994 | PGM3 | 5238 | 8 | 8 | 37 | |
| GSE60625 | PGM3 | 5238 | 0 | 1 | 10 | |
| GSE74703 | PGM3 | 5238 | 2 | 1 | 33 | |
| GSE74704 | PGM3 | 5238 | 0 | 2 | 18 | |
| TCGA | PGM3 | 5238 | 6 | 24 | 66 |
Total number of gains: 33; Total number of losses: 63; Total Number of normals: 392.
Somatic mutations of PGM3:
Generating mutation plots.
Highly correlated genes for PGM3:
Showing top 20/347 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PGM3 | PDGFRA | 0.7645 | 3 | 0 | 3 |
| PGM3 | TMEM117 | 0.757482 | 3 | 0 | 3 |
| PGM3 | GALNT1 | 0.748874 | 3 | 0 | 3 |
| PGM3 | MTPN | 0.744181 | 3 | 0 | 3 |
| PGM3 | GALNT7 | 0.716988 | 3 | 0 | 3 |
| PGM3 | AGPAT5 | 0.708283 | 3 | 0 | 3 |
| PGM3 | IRAK2 | 0.703755 | 3 | 0 | 3 |
| PGM3 | ELK3 | 0.690547 | 4 | 0 | 3 |
| PGM3 | SLC38A4 | 0.688333 | 3 | 0 | 3 |
| PGM3 | LDHD | 0.687879 | 3 | 0 | 3 |
| PGM3 | LYSMD3 | 0.684437 | 4 | 0 | 3 |
| PGM3 | RASGRP1 | 0.683618 | 4 | 0 | 3 |
| PGM3 | RALB | 0.676372 | 4 | 0 | 3 |
| PGM3 | USP8 | 0.674373 | 3 | 0 | 3 |
| PGM3 | SLC9A6 | 0.673545 | 3 | 0 | 3 |
| PGM3 | LIMS1 | 0.673393 | 3 | 0 | 3 |
| PGM3 | TNFRSF19 | 0.672917 | 3 | 0 | 3 |
| PGM3 | DHX32 | 0.670382 | 4 | 0 | 3 |
| PGM3 | MYO1E | 0.668408 | 4 | 0 | 3 |
| PGM3 | VAMP7 | 0.66569 | 5 | 0 | 4 |
For details and further investigation, click here
