| Full name: polypeptide N-acetylgalactosaminyltransferase 1 | Alias Symbol: GalNAc-T1 | ||
| Type: protein-coding gene | Cytoband: 18q12.2 | ||
| Entrez ID: 2589 | HGNC ID: HGNC:4123 | Ensembl Gene: ENSG00000141429 | OMIM ID: 602273 |
| Drug and gene relationship at DGIdb | |||
Expression of GALNT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GALNT1 | 2589 | 1568618_a_at | -0.5211 | 0.3107 | |
| GSE20347 | GALNT1 | 2589 | 201722_s_at | -1.0083 | 0.0001 | |
| GSE23400 | GALNT1 | 2589 | 201722_s_at | -0.6106 | 0.0000 | |
| GSE26886 | GALNT1 | 2589 | 1568618_a_at | -2.2729 | 0.0000 | |
| GSE29001 | GALNT1 | 2589 | 201724_s_at | -0.7107 | 0.0307 | |
| GSE38129 | GALNT1 | 2589 | 201722_s_at | -0.6074 | 0.0044 | |
| GSE45670 | GALNT1 | 2589 | 1568618_a_at | -0.1389 | 0.5577 | |
| GSE53622 | GALNT1 | 2589 | 19352 | -0.5995 | 0.0000 | |
| GSE53624 | GALNT1 | 2589 | 19352 | -0.8470 | 0.0000 | |
| GSE63941 | GALNT1 | 2589 | 201722_s_at | -1.3246 | 0.0712 | |
| GSE77861 | GALNT1 | 2589 | 201722_s_at | -1.0595 | 0.0678 | |
| GSE97050 | GALNT1 | 2589 | A_33_P3210218 | -0.1267 | 0.7411 | |
| SRP007169 | GALNT1 | 2589 | RNAseq | -1.8196 | 0.0001 | |
| SRP008496 | GALNT1 | 2589 | RNAseq | -1.1679 | 0.0032 | |
| SRP064894 | GALNT1 | 2589 | RNAseq | -1.2992 | 0.0000 | |
| SRP133303 | GALNT1 | 2589 | RNAseq | -0.3209 | 0.0789 | |
| SRP159526 | GALNT1 | 2589 | RNAseq | -0.6645 | 0.1858 | |
| SRP193095 | GALNT1 | 2589 | RNAseq | -1.2900 | 0.0000 | |
| SRP219564 | GALNT1 | 2589 | RNAseq | -1.2308 | 0.0137 | |
| TCGA | GALNT1 | 2589 | RNAseq | 0.1072 | 0.0724 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by GALNT1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GALNT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GALNT1 | 2589 | 2 | 5 | 23 | |
| GSE20123 | GALNT1 | 2589 | 2 | 5 | 23 | |
| GSE43470 | GALNT1 | 2589 | 0 | 3 | 40 | |
| GSE46452 | GALNT1 | 2589 | 1 | 25 | 33 | |
| GSE47630 | GALNT1 | 2589 | 5 | 20 | 15 | |
| GSE54993 | GALNT1 | 2589 | 7 | 1 | 62 | |
| GSE54994 | GALNT1 | 2589 | 1 | 16 | 36 | |
| GSE60625 | GALNT1 | 2589 | 0 | 4 | 7 | |
| GSE74703 | GALNT1 | 2589 | 0 | 3 | 33 | |
| GSE74704 | GALNT1 | 2589 | 1 | 4 | 15 | |
| TCGA | GALNT1 | 2589 | 16 | 38 | 42 |
Total number of gains: 35; Total number of losses: 124; Total Number of normals: 329.
Somatic mutations of GALNT1:
Generating mutation plots.
Highly correlated genes for GALNT1:
Showing top 20/1297 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GALNT1 | CNFN | 0.791035 | 6 | 0 | 6 |
| GALNT1 | C15orf48 | 0.771332 | 6 | 0 | 6 |
| GALNT1 | SH3PXD2A-AS1 | 0.76823 | 4 | 0 | 4 |
| GALNT1 | CYSRT1 | 0.761752 | 6 | 0 | 6 |
| GALNT1 | CAPNS2 | 0.751313 | 4 | 0 | 4 |
| GALNT1 | PGM3 | 0.748874 | 3 | 0 | 3 |
| GALNT1 | LYNX1 | 0.748389 | 6 | 0 | 6 |
| GALNT1 | SCEL | 0.743388 | 10 | 0 | 10 |
| GALNT1 | TMEM45B | 0.742457 | 7 | 0 | 7 |
| GALNT1 | CAPN14 | 0.741532 | 6 | 0 | 6 |
| GALNT1 | SPINK7 | 0.739704 | 6 | 0 | 6 |
| GALNT1 | ECM1 | 0.738823 | 10 | 0 | 10 |
| GALNT1 | RANBP9 | 0.738208 | 12 | 0 | 11 |
| GALNT1 | PRSS2 | 0.738176 | 8 | 0 | 7 |
| GALNT1 | TMPRSS11E | 0.735722 | 10 | 0 | 10 |
| GALNT1 | VPS4B | 0.734625 | 13 | 0 | 11 |
| GALNT1 | TMPRSS11B | 0.733926 | 6 | 0 | 6 |
| GALNT1 | MCEE | 0.73196 | 6 | 0 | 6 |
| GALNT1 | USP6NL | 0.731551 | 11 | 0 | 11 |
| GALNT1 | C18orf25 | 0.729781 | 11 | 0 | 11 |
For details and further investigation, click here
