| Full name: ETS transcription factor ELK3 | Alias Symbol: ERP|NET|SAP2 | ||
| Type: protein-coding gene | Cytoband: 12q23.1 | ||
| Entrez ID: 2004 | HGNC ID: HGNC:3325 | Ensembl Gene: ENSG00000111145 | OMIM ID: 600247 |
| Drug and gene relationship at DGIdb | |||
Expression of ELK3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ELK3 | 2004 | 221773_at | -0.4899 | 0.4064 | |
| GSE20347 | ELK3 | 2004 | 221773_at | -1.0582 | 0.0000 | |
| GSE23400 | ELK3 | 2004 | 221773_at | -0.7200 | 0.0000 | |
| GSE26886 | ELK3 | 2004 | 221773_at | -0.8973 | 0.0005 | |
| GSE29001 | ELK3 | 2004 | 221773_at | -0.6552 | 0.0473 | |
| GSE38129 | ELK3 | 2004 | 221773_at | -0.8099 | 0.0000 | |
| GSE45670 | ELK3 | 2004 | 221773_at | -0.4781 | 0.0159 | |
| GSE53622 | ELK3 | 2004 | 41203 | -0.4650 | 0.0000 | |
| GSE53624 | ELK3 | 2004 | 41203 | -0.6193 | 0.0000 | |
| GSE63941 | ELK3 | 2004 | 221773_at | -1.6231 | 0.0299 | |
| GSE77861 | ELK3 | 2004 | 221773_at | -0.7497 | 0.0182 | |
| GSE97050 | ELK3 | 2004 | A_23_P338325 | 0.4650 | 0.3844 | |
| SRP007169 | ELK3 | 2004 | RNAseq | -0.6040 | 0.1327 | |
| SRP008496 | ELK3 | 2004 | RNAseq | -0.5975 | 0.0117 | |
| SRP064894 | ELK3 | 2004 | RNAseq | -0.4716 | 0.0156 | |
| SRP133303 | ELK3 | 2004 | RNAseq | -0.4331 | 0.0055 | |
| SRP159526 | ELK3 | 2004 | RNAseq | -0.8359 | 0.0000 | |
| SRP193095 | ELK3 | 2004 | RNAseq | -0.4426 | 0.0112 | |
| SRP219564 | ELK3 | 2004 | RNAseq | -0.5491 | 0.0988 | |
| TCGA | ELK3 | 2004 | RNAseq | 0.1543 | 0.0300 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by ELK3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ELK3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ELK3 | 2004 | 3 | 2 | 25 | |
| GSE20123 | ELK3 | 2004 | 3 | 2 | 25 | |
| GSE43470 | ELK3 | 2004 | 3 | 0 | 40 | |
| GSE46452 | ELK3 | 2004 | 9 | 1 | 49 | |
| GSE47630 | ELK3 | 2004 | 9 | 1 | 30 | |
| GSE54993 | ELK3 | 2004 | 0 | 5 | 65 | |
| GSE54994 | ELK3 | 2004 | 4 | 1 | 48 | |
| GSE60625 | ELK3 | 2004 | 0 | 0 | 11 | |
| GSE74703 | ELK3 | 2004 | 3 | 0 | 33 | |
| GSE74704 | ELK3 | 2004 | 1 | 2 | 17 | |
| TCGA | ELK3 | 2004 | 18 | 10 | 68 |
Total number of gains: 53; Total number of losses: 24; Total Number of normals: 411.
Somatic mutations of ELK3:
Generating mutation plots.
Highly correlated genes for ELK3:
Showing top 20/1283 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ELK3 | RNFT1 | 0.827157 | 3 | 0 | 3 |
| ELK3 | GTF3C6 | 0.79976 | 3 | 0 | 3 |
| ELK3 | ACTR2 | 0.770705 | 3 | 0 | 3 |
| ELK3 | SLC16A14 | 0.73988 | 3 | 0 | 3 |
| ELK3 | TXNDC9 | 0.736557 | 3 | 0 | 3 |
| ELK3 | ZMYM2 | 0.721943 | 4 | 0 | 4 |
| ELK3 | SNX14 | 0.721522 | 4 | 0 | 4 |
| ELK3 | TMOD3 | 0.718633 | 10 | 0 | 10 |
| ELK3 | SMC5 | 0.717439 | 3 | 0 | 3 |
| ELK3 | ELOVL1 | 0.716172 | 3 | 0 | 3 |
| ELK3 | TMEM167B | 0.715691 | 3 | 0 | 3 |
| ELK3 | SPAG17 | 0.715376 | 3 | 0 | 3 |
| ELK3 | SUSD1 | 0.713133 | 4 | 0 | 4 |
| ELK3 | MRPL44 | 0.707615 | 4 | 0 | 3 |
| ELK3 | CCNYL1 | 0.707354 | 6 | 0 | 6 |
| ELK3 | EI24 | 0.705581 | 3 | 0 | 3 |
| ELK3 | TMEM41B | 0.704622 | 3 | 0 | 3 |
| ELK3 | CNN3 | 0.700986 | 9 | 0 | 9 |
| ELK3 | CPVL | 0.700497 | 4 | 0 | 4 |
| ELK3 | COPG2 | 0.699716 | 3 | 0 | 3 |
For details and further investigation, click here
