| Full name: solute carrier family 38 member 4 | Alias Symbol: PAAT|NAT3|ATA3 | ||
| Type: protein-coding gene | Cytoband: 12q13.11 | ||
| Entrez ID: 55089 | HGNC ID: HGNC:14679 | Ensembl Gene: ENSG00000139209 | OMIM ID: 608065 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC38A4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC38A4 | 55089 | 220786_s_at | -0.7401 | 0.2301 | |
| GSE20347 | SLC38A4 | 55089 | 220786_s_at | -0.2050 | 0.0133 | |
| GSE23400 | SLC38A4 | 55089 | 220786_s_at | -0.0264 | 0.1593 | |
| GSE26886 | SLC38A4 | 55089 | 220786_s_at | -0.6502 | 0.0426 | |
| GSE29001 | SLC38A4 | 55089 | 220786_s_at | -0.0346 | 0.8711 | |
| GSE38129 | SLC38A4 | 55089 | 220786_s_at | -0.1265 | 0.1203 | |
| GSE45670 | SLC38A4 | 55089 | 220786_s_at | -0.3366 | 0.5317 | |
| GSE53622 | SLC38A4 | 55089 | 29189 | -0.7546 | 0.0051 | |
| GSE53624 | SLC38A4 | 55089 | 29189 | -0.7908 | 0.0000 | |
| GSE63941 | SLC38A4 | 55089 | 220786_s_at | -3.7460 | 0.0003 | |
| GSE77861 | SLC38A4 | 55089 | 1555345_at | -0.0143 | 0.8815 | |
| GSE97050 | SLC38A4 | 55089 | A_24_P321581 | 1.3103 | 0.1257 | |
| SRP007169 | SLC38A4 | 55089 | RNAseq | 1.7103 | 0.0245 | |
| SRP133303 | SLC38A4 | 55089 | RNAseq | 0.4221 | 0.3053 | |
| SRP159526 | SLC38A4 | 55089 | RNAseq | -2.0066 | 0.0045 | |
| SRP193095 | SLC38A4 | 55089 | RNAseq | -0.7370 | 0.0005 | |
| TCGA | SLC38A4 | 55089 | RNAseq | 0.7870 | 0.0241 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by SLC38A4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC38A4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC38A4 | 55089 | 7 | 1 | 22 | |
| GSE20123 | SLC38A4 | 55089 | 7 | 1 | 22 | |
| GSE43470 | SLC38A4 | 55089 | 3 | 1 | 39 | |
| GSE46452 | SLC38A4 | 55089 | 8 | 1 | 50 | |
| GSE47630 | SLC38A4 | 55089 | 11 | 2 | 27 | |
| GSE54993 | SLC38A4 | 55089 | 0 | 5 | 65 | |
| GSE54994 | SLC38A4 | 55089 | 5 | 2 | 46 | |
| GSE60625 | SLC38A4 | 55089 | 0 | 0 | 11 | |
| GSE74703 | SLC38A4 | 55089 | 3 | 1 | 32 | |
| GSE74704 | SLC38A4 | 55089 | 3 | 1 | 16 | |
| TCGA | SLC38A4 | 55089 | 16 | 12 | 68 |
Total number of gains: 63; Total number of losses: 27; Total Number of normals: 398.
Somatic mutations of SLC38A4:
Generating mutation plots.
Highly correlated genes for SLC38A4:
Showing top 20/284 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC38A4 | DPY19L3 | 0.734311 | 3 | 0 | 3 |
| SLC38A4 | ITGB5 | 0.727901 | 3 | 0 | 3 |
| SLC38A4 | ANKRD44 | 0.696091 | 3 | 0 | 3 |
| SLC38A4 | PGM3 | 0.688333 | 3 | 0 | 3 |
| SLC38A4 | PDXDC1 | 0.687958 | 3 | 0 | 3 |
| SLC38A4 | RNF149 | 0.686107 | 3 | 0 | 3 |
| SLC38A4 | PRPF38B | 0.663664 | 3 | 0 | 3 |
| SLC38A4 | RAPGEF2 | 0.660814 | 3 | 0 | 3 |
| SLC38A4 | ZDHHC5 | 0.659725 | 4 | 0 | 4 |
| SLC38A4 | RNFT1 | 0.659343 | 3 | 0 | 3 |
| SLC38A4 | PTPN23 | 0.658818 | 3 | 0 | 3 |
| SLC38A4 | RAB7B | 0.657809 | 3 | 0 | 3 |
| SLC38A4 | ATG9B | 0.649377 | 3 | 0 | 3 |
| SLC38A4 | MAGI1 | 0.647843 | 4 | 0 | 3 |
| SLC38A4 | RARS2 | 0.645528 | 3 | 0 | 3 |
| SLC38A4 | LACTB | 0.638668 | 4 | 0 | 3 |
| SLC38A4 | WDFY1 | 0.634992 | 4 | 0 | 3 |
| SLC38A4 | ARSD | 0.628963 | 3 | 0 | 3 |
| SLC38A4 | CD109 | 0.626801 | 3 | 0 | 3 |
| SLC38A4 | ANGPTL4 | 0.625832 | 3 | 0 | 3 |
For details and further investigation, click here
