| Full name: PHD finger protein 11 | Alias Symbol: NY-REN-34|BCAP|IGER | ||
| Type: protein-coding gene | Cytoband: 13q14.2 | ||
| Entrez ID: 51131 | HGNC ID: HGNC:17024 | Ensembl Gene: ENSG00000136147 | OMIM ID: 607796 |
| Drug and gene relationship at DGIdb | |||
Expression of PHF11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PHF11 | 51131 | 221816_s_at | -0.4655 | 0.3789 | |
| GSE20347 | PHF11 | 51131 | 221816_s_at | -0.4292 | 0.0074 | |
| GSE23400 | PHF11 | 51131 | 221816_s_at | -0.0037 | 0.9709 | |
| GSE26886 | PHF11 | 51131 | 221816_s_at | 0.1434 | 0.6580 | |
| GSE29001 | PHF11 | 51131 | 221816_s_at | -0.2259 | 0.3816 | |
| GSE38129 | PHF11 | 51131 | 221816_s_at | -0.4400 | 0.0001 | |
| GSE45670 | PHF11 | 51131 | 221816_s_at | 0.0054 | 0.9847 | |
| GSE53622 | PHF11 | 51131 | 20978 | -0.0765 | 0.3483 | |
| GSE53624 | PHF11 | 51131 | 20978 | -0.2475 | 0.0000 | |
| GSE63941 | PHF11 | 51131 | 221816_s_at | -2.0283 | 0.0846 | |
| GSE77861 | PHF11 | 51131 | 221816_s_at | -0.2114 | 0.5119 | |
| GSE97050 | PHF11 | 51131 | A_23_P65174 | -0.0406 | 0.8894 | |
| SRP007169 | PHF11 | 51131 | RNAseq | -0.8124 | 0.0193 | |
| SRP008496 | PHF11 | 51131 | RNAseq | -0.8050 | 0.0002 | |
| SRP064894 | PHF11 | 51131 | RNAseq | 0.1130 | 0.4169 | |
| SRP133303 | PHF11 | 51131 | RNAseq | -0.2351 | 0.0819 | |
| SRP159526 | PHF11 | 51131 | RNAseq | -1.2082 | 0.0004 | |
| SRP193095 | PHF11 | 51131 | RNAseq | 0.0089 | 0.9465 | |
| SRP219564 | PHF11 | 51131 | RNAseq | -0.1521 | 0.4940 | |
| TCGA | PHF11 | 51131 | RNAseq | -0.0526 | 0.4223 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PHF11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PHF11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PHF11 | 51131 | 1 | 13 | 16 | |
| GSE20123 | PHF11 | 51131 | 1 | 12 | 17 | |
| GSE43470 | PHF11 | 51131 | 3 | 13 | 27 | |
| GSE46452 | PHF11 | 51131 | 0 | 32 | 27 | |
| GSE47630 | PHF11 | 51131 | 2 | 27 | 11 | |
| GSE54993 | PHF11 | 51131 | 12 | 2 | 56 | |
| GSE54994 | PHF11 | 51131 | 2 | 14 | 37 | |
| GSE60625 | PHF11 | 51131 | 0 | 3 | 8 | |
| GSE74703 | PHF11 | 51131 | 3 | 10 | 23 | |
| GSE74704 | PHF11 | 51131 | 0 | 9 | 11 | |
| TCGA | PHF11 | 51131 | 9 | 38 | 49 |
Total number of gains: 33; Total number of losses: 173; Total Number of normals: 282.
Somatic mutations of PHF11:
Generating mutation plots.
Highly correlated genes for PHF11:
Showing top 20/333 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PHF11 | GALNT11 | 0.802985 | 3 | 0 | 3 |
| PHF11 | BDP1 | 0.763567 | 3 | 0 | 3 |
| PHF11 | BIVM | 0.753085 | 3 | 0 | 3 |
| PHF11 | THUMPD1 | 0.732907 | 3 | 0 | 3 |
| PHF11 | ZMAT1 | 0.731301 | 4 | 0 | 4 |
| PHF11 | SLC25A43 | 0.721748 | 3 | 0 | 3 |
| PHF11 | LTBP2 | 0.716989 | 3 | 0 | 3 |
| PHF11 | TADA2B | 0.715127 | 3 | 0 | 3 |
| PHF11 | ZNF383 | 0.714659 | 4 | 0 | 4 |
| PHF11 | UHRF2 | 0.714568 | 4 | 0 | 3 |
| PHF11 | ORAI3 | 0.709975 | 3 | 0 | 3 |
| PHF11 | IFT74 | 0.705718 | 5 | 0 | 5 |
| PHF11 | RABGAP1L | 0.704768 | 3 | 0 | 3 |
| PHF11 | FBXO8 | 0.697385 | 3 | 0 | 3 |
| PHF11 | ATAT1 | 0.691648 | 3 | 0 | 3 |
| PHF11 | PLCE1 | 0.691119 | 3 | 0 | 3 |
| PHF11 | BBS9 | 0.685495 | 4 | 0 | 3 |
| PHF11 | TUBE1 | 0.678649 | 3 | 0 | 3 |
| PHF11 | GPATCH1 | 0.671848 | 3 | 0 | 3 |
| PHF11 | UPF3A | 0.667522 | 6 | 0 | 5 |
For details and further investigation, click here
