| Full name: alpha tubulin acetyltransferase 1 | Alias Symbol: FLJ13158|Em:AB023049.7|MEC17 | ||
| Type: protein-coding gene | Cytoband: 6p21.33 | ||
| Entrez ID: 79969 | HGNC ID: HGNC:21186 | Ensembl Gene: ENSG00000137343 | OMIM ID: 615556 |
| Drug and gene relationship at DGIdb | |||
Expression of ATAT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATAT1 | 79969 | 218874_s_at | 0.1380 | 0.7946 | |
| GSE20347 | ATAT1 | 79969 | 218874_s_at | 0.1157 | 0.3790 | |
| GSE23400 | ATAT1 | 79969 | 218874_s_at | -0.0687 | 0.2198 | |
| GSE26886 | ATAT1 | 79969 | 218874_s_at | 0.1948 | 0.1247 | |
| GSE29001 | ATAT1 | 79969 | 218874_s_at | -0.2110 | 0.2934 | |
| GSE38129 | ATAT1 | 79969 | 218874_s_at | 0.0819 | 0.4709 | |
| GSE45670 | ATAT1 | 79969 | 228510_at | 0.2135 | 0.0788 | |
| GSE53622 | ATAT1 | 79969 | 27089 | 0.5403 | 0.0000 | |
| GSE53624 | ATAT1 | 79969 | 27089 | 0.4050 | 0.0000 | |
| GSE63941 | ATAT1 | 79969 | 228510_at | 0.2815 | 0.3526 | |
| GSE77861 | ATAT1 | 79969 | 218874_s_at | -0.0534 | 0.6267 | |
| GSE97050 | ATAT1 | 79969 | A_23_P70509 | 0.5532 | 0.1344 | |
| SRP007169 | ATAT1 | 79969 | RNAseq | 1.1062 | 0.1090 | |
| SRP064894 | ATAT1 | 79969 | RNAseq | 0.3090 | 0.1242 | |
| SRP133303 | ATAT1 | 79969 | RNAseq | 0.2018 | 0.3101 | |
| SRP159526 | ATAT1 | 79969 | RNAseq | 0.7055 | 0.1032 | |
| SRP193095 | ATAT1 | 79969 | RNAseq | 0.0851 | 0.5141 | |
| SRP219564 | ATAT1 | 79969 | RNAseq | 0.2096 | 0.4511 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ATAT1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of ATAT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATAT1 | 79969 | 5 | 1 | 24 | |
| GSE20123 | ATAT1 | 79969 | 5 | 1 | 24 | |
| GSE43470 | ATAT1 | 79969 | 5 | 1 | 37 | |
| GSE46452 | ATAT1 | 79969 | 1 | 10 | 48 | |
| GSE47630 | ATAT1 | 79969 | 7 | 3 | 30 | |
| GSE54993 | ATAT1 | 79969 | 2 | 1 | 67 | |
| GSE54994 | ATAT1 | 79969 | 11 | 4 | 38 | |
| GSE60625 | ATAT1 | 79969 | 0 | 1 | 10 | |
| GSE74703 | ATAT1 | 79969 | 5 | 0 | 31 | |
| GSE74704 | ATAT1 | 79969 | 2 | 0 | 18 | |
| TCGA | ATAT1 | 79969 | 18 | 16 | 62 |
Total number of gains: 61; Total number of losses: 38; Total Number of normals: 389.
Somatic mutations of ATAT1:
Generating mutation plots.
Highly correlated genes for ATAT1:
Showing top 20/364 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATAT1 | SCAF1 | 0.770196 | 3 | 0 | 3 |
| ATAT1 | RFX1 | 0.765703 | 3 | 0 | 3 |
| ATAT1 | RAVER1 | 0.756713 | 3 | 0 | 3 |
| ATAT1 | ADCK1 | 0.75547 | 3 | 0 | 3 |
| ATAT1 | FBXO6 | 0.754685 | 3 | 0 | 3 |
| ATAT1 | YIPF3 | 0.749739 | 3 | 0 | 3 |
| ATAT1 | TNFSF8 | 0.744973 | 3 | 0 | 3 |
| ATAT1 | CIDEC | 0.735247 | 4 | 0 | 4 |
| ATAT1 | TMEM214 | 0.734283 | 3 | 0 | 3 |
| ATAT1 | CCDC167 | 0.718888 | 3 | 0 | 3 |
| ATAT1 | RHOH | 0.713044 | 3 | 0 | 3 |
| ATAT1 | NACC1 | 0.71098 | 3 | 0 | 3 |
| ATAT1 | ETS1 | 0.709136 | 3 | 0 | 3 |
| ATAT1 | ARAF | 0.704048 | 3 | 0 | 3 |
| ATAT1 | PHF11 | 0.691648 | 3 | 0 | 3 |
| ATAT1 | SHF | 0.690685 | 3 | 0 | 3 |
| ATAT1 | TRIM62 | 0.686118 | 3 | 0 | 3 |
| ATAT1 | FUBP1 | 0.683692 | 4 | 0 | 3 |
| ATAT1 | MINK1 | 0.682829 | 4 | 0 | 3 |
| ATAT1 | R3HDM2 | 0.680769 | 3 | 0 | 3 |
For details and further investigation, click here
