| Full name: intraflagellar transport 74 | Alias Symbol: CMG1|CMG-1|FLJ22621 | ||
| Type: protein-coding gene | Cytoband: 9p21.2 | ||
| Entrez ID: 80173 | HGNC ID: HGNC:21424 | Ensembl Gene: ENSG00000096872 | OMIM ID: 608040 |
| Drug and gene relationship at DGIdb | |||
Expression of IFT74:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IFT74 | 80173 | 219174_at | -0.4650 | 0.3490 | |
| GSE20347 | IFT74 | 80173 | 219174_at | -0.4386 | 0.0693 | |
| GSE23400 | IFT74 | 80173 | 219174_at | 0.0754 | 0.3055 | |
| GSE26886 | IFT74 | 80173 | 219174_at | 0.4953 | 0.1689 | |
| GSE29001 | IFT74 | 80173 | 219174_at | -0.3225 | 0.6172 | |
| GSE38129 | IFT74 | 80173 | 219174_at | -0.4287 | 0.0329 | |
| GSE45670 | IFT74 | 80173 | 219174_at | -0.4492 | 0.1729 | |
| GSE53622 | IFT74 | 80173 | 4957 | -0.2917 | 0.0006 | |
| GSE53624 | IFT74 | 80173 | 4957 | -0.1051 | 0.1491 | |
| GSE63941 | IFT74 | 80173 | 219174_at | -1.2433 | 0.1383 | |
| GSE77861 | IFT74 | 80173 | 219174_at | 0.2678 | 0.8035 | |
| GSE97050 | IFT74 | 80173 | A_23_P255714 | -0.5008 | 0.1204 | |
| SRP007169 | IFT74 | 80173 | RNAseq | -0.6702 | 0.2260 | |
| SRP008496 | IFT74 | 80173 | RNAseq | -0.0740 | 0.8679 | |
| SRP064894 | IFT74 | 80173 | RNAseq | -0.2763 | 0.2258 | |
| SRP133303 | IFT74 | 80173 | RNAseq | -0.1752 | 0.3365 | |
| SRP159526 | IFT74 | 80173 | RNAseq | -0.1556 | 0.5357 | |
| SRP193095 | IFT74 | 80173 | RNAseq | -0.3641 | 0.0058 | |
| SRP219564 | IFT74 | 80173 | RNAseq | -0.7190 | 0.1324 | |
| TCGA | IFT74 | 80173 | RNAseq | -0.0162 | 0.9013 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by IFT74 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IFT74:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IFT74 | 80173 | 2 | 14 | 14 | |
| GSE20123 | IFT74 | 80173 | 2 | 14 | 14 | |
| GSE43470 | IFT74 | 80173 | 2 | 11 | 30 | |
| GSE46452 | IFT74 | 80173 | 6 | 18 | 35 | |
| GSE47630 | IFT74 | 80173 | 1 | 22 | 17 | |
| GSE54993 | IFT74 | 80173 | 7 | 0 | 63 | |
| GSE54994 | IFT74 | 80173 | 7 | 15 | 31 | |
| GSE60625 | IFT74 | 80173 | 0 | 0 | 11 | |
| GSE74703 | IFT74 | 80173 | 2 | 8 | 26 | |
| GSE74704 | IFT74 | 80173 | 0 | 11 | 9 | |
| TCGA | IFT74 | 80173 | 16 | 47 | 33 |
Total number of gains: 45; Total number of losses: 160; Total Number of normals: 283.
Somatic mutations of IFT74:
Generating mutation plots.
Highly correlated genes for IFT74:
Showing top 20/445 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IFT74 | THUMPD1 | 0.80071 | 4 | 0 | 3 |
| IFT74 | FNIP1 | 0.752269 | 3 | 0 | 3 |
| IFT74 | CHUK | 0.747946 | 3 | 0 | 3 |
| IFT74 | REV1 | 0.742924 | 3 | 0 | 3 |
| IFT74 | SHPRH | 0.739194 | 4 | 0 | 4 |
| IFT74 | SGMS1 | 0.736565 | 3 | 0 | 3 |
| IFT74 | ACVR2A | 0.735147 | 4 | 0 | 4 |
| IFT74 | TYW3 | 0.727268 | 3 | 0 | 3 |
| IFT74 | DNAJC1 | 0.724283 | 4 | 0 | 3 |
| IFT74 | ZNF627 | 0.721704 | 3 | 0 | 3 |
| IFT74 | RWDD4 | 0.721175 | 4 | 0 | 4 |
| IFT74 | NIPSNAP3A | 0.720492 | 4 | 0 | 3 |
| IFT74 | MTO1 | 0.716671 | 4 | 0 | 3 |
| IFT74 | ZNF292 | 0.716616 | 4 | 0 | 3 |
| IFT74 | MTRF1 | 0.711606 | 3 | 0 | 3 |
| IFT74 | NFAT5 | 0.709148 | 3 | 0 | 3 |
| IFT74 | PHF11 | 0.705718 | 5 | 0 | 5 |
| IFT74 | YTHDF3 | 0.70181 | 3 | 0 | 3 |
| IFT74 | CHD1 | 0.694451 | 4 | 0 | 3 |
| IFT74 | SRPK1 | 0.692216 | 4 | 0 | 4 |
For details and further investigation, click here
