RABGAP1L

 

Full name: RAB GTPase activating protein 1 like Alias Symbol: HHL|TBC1D18|KIAA0471|FLJ38519
Type: protein-coding gene Cytoband: 1q25.1
Entrez ID: 9910 HGNC ID: HGNC:24663 Ensembl Gene: ENSG00000152061 OMIM ID: 609238
Drug and gene relationship at DGIdb

 

Expression of RABGAP1L:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RABGAP1L 9910 203020_at -0.4348 0.2362
GSE20347 RABGAP1L 9910 203020_at -0.8249 0.0029
GSE23400 RABGAP1L 9910 203020_at -0.3590 0.0003
GSE26886 RABGAP1L 9910 203020_at -0.9353 0.0012
GSE29001 RABGAP1L 9910 203020_at -0.4527 0.1885
GSE38129 RABGAP1L 9910 203020_at -0.6588 0.0008
GSE45670 RABGAP1L 9910 203020_at -0.6455 0.0027
GSE53622 RABGAP1L 9910 48772 -0.6485 0.0000
GSE53624 RABGAP1L 9910 48772 -0.9226 0.0000
GSE63941 RABGAP1L 9910 203020_at 0.7287 0.2054
GSE77861 RABGAP1L 9910 203020_at -0.5404 0.0921
GSE97050 RABGAP1L 9910 A_24_P28295 -0.1068 0.6889
SRP007169 RABGAP1L 9910 RNAseq -0.0737 0.8680
SRP008496 RABGAP1L 9910 RNAseq 0.6158 0.0674
SRP064894 RABGAP1L 9910 RNAseq -0.0215 0.9178
SRP133303 RABGAP1L 9910 RNAseq 0.0164 0.9058
SRP159526 RABGAP1L 9910 RNAseq -0.1316 0.7146
SRP193095 RABGAP1L 9910 RNAseq -0.1471 0.1345
SRP219564 RABGAP1L 9910 RNAseq -0.3469 0.5270
TCGA RABGAP1L 9910 RNAseq -0.1488 0.0101

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by RABGAP1L expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of RABGAP1L:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RABGAP1L 9910 12 0 18
GSE20123 RABGAP1L 9910 12 0 18
GSE43470 RABGAP1L 9910 7 2 34
GSE46452 RABGAP1L 9910 3 1 55
GSE47630 RABGAP1L 9910 14 0 26
GSE54993 RABGAP1L 9910 0 6 64
GSE54994 RABGAP1L 9910 15 0 38
GSE60625 RABGAP1L 9910 0 0 11
GSE74703 RABGAP1L 9910 7 2 27
GSE74704 RABGAP1L 9910 5 0 15
TCGA RABGAP1L 9910 43 7 46

Total number of gains: 118; Total number of losses: 18; Total Number of normals: 352.  


 

Somatic mutations of RABGAP1L:

 

Generating mutation plots.

 

Highly correlated genes for RABGAP1L:

 

Showing top 20/1274 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RABGAP1LIFT460.808457303
RABGAP1LRBM200.764006404
RABGAP1LACTR20.760822303
RABGAP1LCDKL10.756343303
RABGAP1LEBPL0.755119404
RABGAP1LMAT2B0.751111303
RABGAP1LATP6V1G10.730911303
RABGAP1LTMEM126A0.727063303
RABGAP1LNUDT90.726959303
RABGAP1LCOG50.726408303
RABGAP1LEIF3E0.724864303
RABGAP1LCOG30.713625303
RABGAP1LZNF8230.71081706
RABGAP1LCAPNS20.708901505
RABGAP1LPHF110.704768303
RABGAP1LRCOR30.70349504
RABGAP1LTET20.703168707
RABGAP1LWDFY10.701018404
RABGAP1LPIGM0.701008303
RABGAP1LBLOC1S20.700903404

For details and further investigation, click here