| Full name: cytochrome c oxidase assembly factor COX20 | Alias Symbol: FLJ43269 | ||
| Type: protein-coding gene | Cytoband: 1q44 | ||
| Entrez ID: 116228 | HGNC ID: HGNC:26970 | Ensembl Gene: ENSG00000203667 | OMIM ID: 614698 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of COX20:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COX20 | 116228 | 224820_at | -0.7100 | 0.2817 | |
| GSE26886 | COX20 | 116228 | 224820_at | 0.7119 | 0.0064 | |
| GSE45670 | COX20 | 116228 | 224820_at | -0.8688 | 0.0002 | |
| GSE63941 | COX20 | 116228 | 224820_at | -0.4204 | 0.4273 | |
| GSE77861 | COX20 | 116228 | 224824_at | 0.2508 | 0.0665 | |
| SRP007169 | COX20 | 116228 | RNAseq | 0.0151 | 0.9675 | |
| SRP008496 | COX20 | 116228 | RNAseq | 0.2527 | 0.3257 | |
| SRP064894 | COX20 | 116228 | RNAseq | -0.2730 | 0.0450 | |
| SRP133303 | COX20 | 116228 | RNAseq | 0.0850 | 0.5915 | |
| SRP159526 | COX20 | 116228 | RNAseq | 0.2597 | 0.2094 | |
| SRP193095 | COX20 | 116228 | RNAseq | -0.0033 | 0.9734 | |
| SRP219564 | COX20 | 116228 | RNAseq | -0.1137 | 0.7512 |
Upregulated datasets: 0; Downregulated datasets: 0.
Copy number change of COX20:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COX20 | 116228 | 7 | 1 | 22 | |
| GSE20123 | COX20 | 116228 | 7 | 1 | 22 | |
| GSE43470 | COX20 | 116228 | 6 | 2 | 35 | |
| GSE46452 | COX20 | 116228 | 4 | 2 | 53 | |
| GSE47630 | COX20 | 116228 | 15 | 0 | 25 | |
| GSE54993 | COX20 | 116228 | 0 | 6 | 64 | |
| GSE54994 | COX20 | 116228 | 18 | 0 | 35 | |
| GSE60625 | COX20 | 116228 | 0 | 0 | 11 | |
| GSE74703 | COX20 | 116228 | 6 | 1 | 29 | |
| GSE74704 | COX20 | 116228 | 2 | 0 | 18 | |
| TCGA | COX20 | 116228 | 46 | 4 | 46 |
Total number of gains: 111; Total number of losses: 17; Total Number of normals: 360.
Somatic mutations of COX20:
Generating mutation plots.
Highly correlated genes for COX20:
Showing top 20/133 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COX20 | PPP1R12A | 0.744364 | 3 | 0 | 3 |
| COX20 | MOAP1 | 0.73797 | 3 | 0 | 3 |
| COX20 | SGCB | 0.720495 | 3 | 0 | 3 |
| COX20 | PRKAB2 | 0.719485 | 3 | 0 | 3 |
| COX20 | RPS27 | 0.714669 | 3 | 0 | 3 |
| COX20 | PPARGC1A | 0.714236 | 3 | 0 | 3 |
| COX20 | PHYH | 0.708769 | 3 | 0 | 3 |
| COX20 | TSPAN2 | 0.677217 | 3 | 0 | 3 |
| COX20 | SVIL | 0.675784 | 3 | 0 | 3 |
| COX20 | PBXIP1 | 0.673864 | 3 | 0 | 3 |
| COX20 | HMCN1 | 0.672283 | 4 | 0 | 3 |
| COX20 | ANO6 | 0.670341 | 3 | 0 | 3 |
| COX20 | MTERF2 | 0.665721 | 3 | 0 | 3 |
| COX20 | PLCB4 | 0.663162 | 3 | 0 | 3 |
| COX20 | ARIH2 | 0.662682 | 3 | 0 | 3 |
| COX20 | CCDC92 | 0.662625 | 3 | 0 | 3 |
| COX20 | WIF1 | 0.660919 | 3 | 0 | 3 |
| COX20 | STON1 | 0.65999 | 3 | 0 | 3 |
| COX20 | SYNM | 0.658878 | 4 | 0 | 3 |
| COX20 | MGST3 | 0.658142 | 4 | 0 | 3 |
For details and further investigation, click here
