| Full name: ubiquitin specific peptidase 42 | Alias Symbol: FLJ12697 | ||
| Type: protein-coding gene | Cytoband: 7p22.1 | ||
| Entrez ID: 84132 | HGNC ID: HGNC:20068 | Ensembl Gene: ENSG00000106346 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of USP42:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | USP42 | 84132 | 226669_at | 0.4541 | 0.1073 | |
| GSE26886 | USP42 | 84132 | 226669_at | 1.2307 | 0.0000 | |
| GSE45670 | USP42 | 84132 | 226669_at | 0.5254 | 0.0001 | |
| GSE53622 | USP42 | 84132 | 82192 | 0.7677 | 0.0000 | |
| GSE53624 | USP42 | 84132 | 82192 | 0.8609 | 0.0000 | |
| GSE63941 | USP42 | 84132 | 226669_at | 0.4255 | 0.3039 | |
| GSE77861 | USP42 | 84132 | 226174_at | 0.0396 | 0.7874 | |
| GSE97050 | USP42 | 84132 | A_24_P135276 | 0.6048 | 0.1450 | |
| SRP007169 | USP42 | 84132 | RNAseq | 1.0540 | 0.0146 | |
| SRP008496 | USP42 | 84132 | RNAseq | 1.1576 | 0.0004 | |
| SRP064894 | USP42 | 84132 | RNAseq | 0.5378 | 0.0009 | |
| SRP133303 | USP42 | 84132 | RNAseq | 0.6804 | 0.0000 | |
| SRP159526 | USP42 | 84132 | RNAseq | 0.7668 | 0.0089 | |
| SRP193095 | USP42 | 84132 | RNAseq | 0.4803 | 0.0000 | |
| SRP219564 | USP42 | 84132 | RNAseq | 0.4956 | 0.1574 | |
| TCGA | USP42 | 84132 | RNAseq | 0.1569 | 0.0043 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by USP42 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of USP42:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | USP42 | 84132 | 14 | 1 | 15 | |
| GSE20123 | USP42 | 84132 | 14 | 1 | 15 | |
| GSE43470 | USP42 | 84132 | 6 | 1 | 36 | |
| GSE46452 | USP42 | 84132 | 13 | 1 | 45 | |
| GSE47630 | USP42 | 84132 | 9 | 1 | 30 | |
| GSE54993 | USP42 | 84132 | 0 | 6 | 64 | |
| GSE54994 | USP42 | 84132 | 20 | 1 | 32 | |
| GSE60625 | USP42 | 84132 | 0 | 0 | 11 | |
| GSE74703 | USP42 | 84132 | 6 | 0 | 30 | |
| GSE74704 | USP42 | 84132 | 9 | 0 | 11 | |
| TCGA | USP42 | 84132 | 55 | 5 | 36 |
Total number of gains: 146; Total number of losses: 17; Total Number of normals: 325.
Somatic mutations of USP42:
Generating mutation plots.
Highly correlated genes for USP42:
Showing top 20/1754 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| USP42 | SPNS1 | 0.83657 | 3 | 0 | 3 |
| USP42 | ZNF668 | 0.798772 | 3 | 0 | 3 |
| USP42 | FAM171B | 0.796974 | 3 | 0 | 3 |
| USP42 | SEC22C | 0.795055 | 3 | 0 | 3 |
| USP42 | LRRK1 | 0.780558 | 3 | 0 | 3 |
| USP42 | RALGAPB | 0.777237 | 3 | 0 | 3 |
| USP42 | RNPS1 | 0.773903 | 6 | 0 | 6 |
| USP42 | STAT2 | 0.772541 | 3 | 0 | 3 |
| USP42 | SCNM1 | 0.77193 | 3 | 0 | 3 |
| USP42 | INPP5B | 0.770566 | 3 | 0 | 3 |
| USP42 | CLCN7 | 0.768606 | 3 | 0 | 3 |
| USP42 | RPS19BP1 | 0.765039 | 3 | 0 | 3 |
| USP42 | PHF5A | 0.761828 | 4 | 0 | 4 |
| USP42 | KIF3B | 0.75437 | 5 | 0 | 5 |
| USP42 | ADAR | 0.753033 | 5 | 0 | 4 |
| USP42 | CD2BP2 | 0.75056 | 3 | 0 | 3 |
| USP42 | COMMD2 | 0.745225 | 3 | 0 | 3 |
| USP42 | ADSL | 0.74405 | 5 | 0 | 5 |
| USP42 | PTCD1 | 0.743875 | 3 | 0 | 3 |
| USP42 | POLA2 | 0.743185 | 6 | 0 | 6 |
For details and further investigation, click here
