| Full name: myosin VA | Alias Symbol: MYO5|GS1|MYR12 | ||
| Type: protein-coding gene | Cytoband: 15q21.2 | ||
| Entrez ID: 4644 | HGNC ID: HGNC:7602 | Ensembl Gene: ENSG00000197535 | OMIM ID: 160777 |
| Drug and gene relationship at DGIdb | |||
Expression of MYO5A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MYO5A | 4644 | 227761_at | 0.6975 | 0.4454 | |
| GSE20347 | MYO5A | 4644 | 204527_at | 1.7637 | 0.0000 | |
| GSE23400 | MYO5A | 4644 | 204527_at | 0.8125 | 0.0000 | |
| GSE26886 | MYO5A | 4644 | 227761_at | 1.7665 | 0.0000 | |
| GSE29001 | MYO5A | 4644 | 204527_at | 1.3189 | 0.0000 | |
| GSE38129 | MYO5A | 4644 | 204527_at | 1.7619 | 0.0000 | |
| GSE45670 | MYO5A | 4644 | 227761_at | 0.7402 | 0.0385 | |
| GSE53622 | MYO5A | 4644 | 122015 | 1.1170 | 0.0000 | |
| GSE53624 | MYO5A | 4644 | 122015 | 1.3999 | 0.0000 | |
| GSE63941 | MYO5A | 4644 | 227761_at | -1.1734 | 0.0334 | |
| GSE77861 | MYO5A | 4644 | 204527_at | 1.5133 | 0.0006 | |
| GSE97050 | MYO5A | 4644 | A_24_P255218 | 0.9517 | 0.0620 | |
| SRP007169 | MYO5A | 4644 | RNAseq | 3.0955 | 0.0000 | |
| SRP008496 | MYO5A | 4644 | RNAseq | 2.9564 | 0.0000 | |
| SRP064894 | MYO5A | 4644 | RNAseq | 1.2641 | 0.0000 | |
| SRP133303 | MYO5A | 4644 | RNAseq | 1.2573 | 0.0000 | |
| SRP159526 | MYO5A | 4644 | RNAseq | 1.2962 | 0.0056 | |
| SRP193095 | MYO5A | 4644 | RNAseq | 1.8840 | 0.0000 | |
| SRP219564 | MYO5A | 4644 | RNAseq | 0.5368 | 0.1212 | |
| TCGA | MYO5A | 4644 | RNAseq | 0.2831 | 0.0005 |
Upregulated datasets: 13; Downregulated datasets: 1.
Survival by MYO5A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MYO5A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MYO5A | 4644 | 5 | 4 | 21 | |
| GSE20123 | MYO5A | 4644 | 5 | 4 | 21 | |
| GSE43470 | MYO5A | 4644 | 4 | 3 | 36 | |
| GSE46452 | MYO5A | 4644 | 3 | 7 | 49 | |
| GSE47630 | MYO5A | 4644 | 8 | 10 | 22 | |
| GSE54993 | MYO5A | 4644 | 5 | 6 | 59 | |
| GSE54994 | MYO5A | 4644 | 5 | 7 | 41 | |
| GSE60625 | MYO5A | 4644 | 4 | 0 | 7 | |
| GSE74703 | MYO5A | 4644 | 4 | 2 | 30 | |
| GSE74704 | MYO5A | 4644 | 2 | 3 | 15 | |
| TCGA | MYO5A | 4644 | 9 | 17 | 70 |
Total number of gains: 54; Total number of losses: 63; Total Number of normals: 371.
Somatic mutations of MYO5A:
Generating mutation plots.
Highly correlated genes for MYO5A:
Showing top 20/1687 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MYO5A | PLEKHA3 | 0.822345 | 3 | 0 | 3 |
| MYO5A | WDR54 | 0.815804 | 7 | 0 | 7 |
| MYO5A | C2orf69 | 0.809041 | 3 | 0 | 3 |
| MYO5A | FADS1 | 0.785989 | 3 | 0 | 3 |
| MYO5A | SPON2 | 0.783529 | 3 | 0 | 3 |
| MYO5A | NACC1 | 0.781864 | 3 | 0 | 3 |
| MYO5A | LRRC8C | 0.779118 | 3 | 0 | 3 |
| MYO5A | SUZ12 | 0.778897 | 3 | 0 | 3 |
| MYO5A | XPR1 | 0.778367 | 7 | 0 | 7 |
| MYO5A | A4GALT | 0.778352 | 3 | 0 | 3 |
| MYO5A | SH3RF3 | 0.766795 | 4 | 0 | 4 |
| MYO5A | PLEKHG2 | 0.766437 | 3 | 0 | 3 |
| MYO5A | GMCL1 | 0.766142 | 3 | 0 | 3 |
| MYO5A | LIX1L | 0.765184 | 3 | 0 | 3 |
| MYO5A | TGFBI | 0.760626 | 12 | 0 | 11 |
| MYO5A | RAB34 | 0.758945 | 3 | 0 | 3 |
| MYO5A | ARPC1B | 0.757828 | 11 | 0 | 11 |
| MYO5A | ABCB6 | 0.75221 | 3 | 0 | 3 |
| MYO5A | SLC38A6 | 0.745117 | 9 | 0 | 9 |
| MYO5A | TENM2 | 0.743971 | 6 | 0 | 6 |
For details and further investigation, click here
