| Full name: sarcolemma associated protein | Alias Symbol: SLAP|KIAA1601 | ||
| Type: protein-coding gene | Cytoband: 3p14.3 | ||
| Entrez ID: 7871 | HGNC ID: HGNC:16643 | Ensembl Gene: ENSG00000163681 | OMIM ID: 602701 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SLMAP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLMAP | 7871 | 225243_s_at | -1.3211 | 0.0695 | |
| GSE26886 | SLMAP | 7871 | 225243_s_at | -1.0814 | 0.0000 | |
| GSE45670 | SLMAP | 7871 | 225243_s_at | -1.2089 | 0.0000 | |
| GSE53622 | SLMAP | 7871 | 92483 | -1.8104 | 0.0000 | |
| GSE53624 | SLMAP | 7871 | 92483 | -1.5268 | 0.0000 | |
| GSE63941 | SLMAP | 7871 | 225243_s_at | -0.8373 | 0.0884 | |
| GSE77861 | SLMAP | 7871 | 225243_s_at | -0.4396 | 0.0299 | |
| GSE97050 | SLMAP | 7871 | A_24_P942773 | -2.0002 | 0.0643 | |
| SRP007169 | SLMAP | 7871 | RNAseq | -0.6809 | 0.0638 | |
| SRP008496 | SLMAP | 7871 | RNAseq | -0.2508 | 0.2924 | |
| SRP064894 | SLMAP | 7871 | RNAseq | -1.2197 | 0.0000 | |
| SRP133303 | SLMAP | 7871 | RNAseq | -0.9157 | 0.0000 | |
| SRP159526 | SLMAP | 7871 | RNAseq | -1.2191 | 0.0021 | |
| SRP193095 | SLMAP | 7871 | RNAseq | -0.6144 | 0.0000 | |
| SRP219564 | SLMAP | 7871 | RNAseq | -1.5769 | 0.0429 | |
| TCGA | SLMAP | 7871 | RNAseq | -0.3509 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by SLMAP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLMAP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLMAP | 7871 | 0 | 17 | 13 | |
| GSE20123 | SLMAP | 7871 | 0 | 18 | 12 | |
| GSE43470 | SLMAP | 7871 | 0 | 17 | 26 | |
| GSE46452 | SLMAP | 7871 | 2 | 17 | 40 | |
| GSE47630 | SLMAP | 7871 | 1 | 24 | 15 | |
| GSE54993 | SLMAP | 7871 | 6 | 2 | 62 | |
| GSE54994 | SLMAP | 7871 | 0 | 32 | 21 | |
| GSE60625 | SLMAP | 7871 | 5 | 0 | 6 | |
| GSE74703 | SLMAP | 7871 | 0 | 14 | 22 | |
| GSE74704 | SLMAP | 7871 | 0 | 11 | 9 | |
| TCGA | SLMAP | 7871 | 0 | 79 | 17 |
Total number of gains: 14; Total number of losses: 231; Total Number of normals: 243.
Somatic mutations of SLMAP:
Generating mutation plots.
Highly correlated genes for SLMAP:
Showing top 20/1602 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLMAP | RASSF3 | 0.861057 | 5 | 0 | 5 |
| SLMAP | HPSE2 | 0.850914 | 5 | 0 | 5 |
| SLMAP | SLC2A4 | 0.845073 | 3 | 0 | 3 |
| SLMAP | PCP4 | 0.843329 | 5 | 0 | 5 |
| SLMAP | WBP4 | 0.836127 | 3 | 0 | 3 |
| SLMAP | CLEC3B | 0.835973 | 3 | 0 | 3 |
| SLMAP | SLITRK3 | 0.834594 | 5 | 0 | 5 |
| SLMAP | RAP1A | 0.833081 | 7 | 0 | 7 |
| SLMAP | PYGM | 0.831995 | 5 | 0 | 5 |
| SLMAP | SLC8A1 | 0.827038 | 3 | 0 | 3 |
| SLMAP | C1QTNF7 | 0.820403 | 5 | 0 | 5 |
| SLMAP | CKMT2 | 0.815677 | 5 | 0 | 5 |
| SLMAP | XKR4 | 0.815646 | 5 | 0 | 5 |
| SLMAP | CHRDL1 | 0.812004 | 4 | 0 | 4 |
| SLMAP | BCHE | 0.811252 | 5 | 0 | 5 |
| SLMAP | MYOC | 0.802679 | 5 | 0 | 5 |
| SLMAP | OGN | 0.802128 | 5 | 0 | 5 |
| SLMAP | PDK4 | 0.798839 | 4 | 0 | 4 |
| SLMAP | CYP21A2 | 0.798217 | 3 | 0 | 3 |
| SLMAP | PPP1R12A | 0.797943 | 7 | 0 | 7 |
For details and further investigation, click here
