| Full name: phosphatidylinositol specific phospholipase C X domain containing 2 | Alias Symbol: FLJ31579 | ||
| Type: protein-coding gene | Cytoband: 3q13.2 | ||
| Entrez ID: 257068 | HGNC ID: HGNC:26462 | Ensembl Gene: ENSG00000240891 | OMIM ID: 617015 |
| Drug and gene relationship at DGIdb | |||
Expression of PLCXD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PLCXD2 | 257068 | 1553281_at | 0.1919 | 0.6354 | |
| GSE26886 | PLCXD2 | 257068 | 235230_at | 0.1252 | 0.7945 | |
| GSE45670 | PLCXD2 | 257068 | 235230_at | 0.2896 | 0.3830 | |
| GSE53622 | PLCXD2 | 257068 | 16145 | 0.0678 | 0.6084 | |
| GSE53624 | PLCXD2 | 257068 | 16145 | 0.0220 | 0.8542 | |
| GSE63941 | PLCXD2 | 257068 | 235230_at | 1.4644 | 0.0182 | |
| GSE77861 | PLCXD2 | 257068 | 1553281_at | -0.0875 | 0.5442 | |
| GSE97050 | PLCXD2 | 257068 | A_33_P3214339 | 0.0781 | 0.8183 | |
| SRP007169 | PLCXD2 | 257068 | RNAseq | -1.1558 | 0.1521 | |
| SRP133303 | PLCXD2 | 257068 | RNAseq | 0.2650 | 0.5003 | |
| SRP193095 | PLCXD2 | 257068 | RNAseq | 0.1525 | 0.5086 | |
| TCGA | PLCXD2 | 257068 | RNAseq | 0.2106 | 0.1851 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PLCXD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PLCXD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PLCXD2 | 257068 | 19 | 1 | 10 | |
| GSE20123 | PLCXD2 | 257068 | 19 | 1 | 10 | |
| GSE43470 | PLCXD2 | 257068 | 20 | 1 | 22 | |
| GSE46452 | PLCXD2 | 257068 | 12 | 6 | 41 | |
| GSE47630 | PLCXD2 | 257068 | 16 | 6 | 18 | |
| GSE54993 | PLCXD2 | 257068 | 2 | 5 | 63 | |
| GSE54994 | PLCXD2 | 257068 | 29 | 4 | 20 | |
| GSE60625 | PLCXD2 | 257068 | 0 | 6 | 5 | |
| GSE74703 | PLCXD2 | 257068 | 16 | 1 | 19 | |
| GSE74704 | PLCXD2 | 257068 | 13 | 1 | 6 | |
| TCGA | PLCXD2 | 257068 | 52 | 9 | 35 |
Total number of gains: 198; Total number of losses: 41; Total Number of normals: 249.
Somatic mutations of PLCXD2:
Generating mutation plots.
Highly correlated genes for PLCXD2:
Showing top 20/22 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PLCXD2 | C20orf96 | 0.690302 | 3 | 0 | 3 |
| PLCXD2 | AGTPBP1 | 0.671803 | 3 | 0 | 3 |
| PLCXD2 | MCU | 0.660668 | 3 | 0 | 3 |
| PLCXD2 | WBP2 | 0.65965 | 3 | 0 | 3 |
| PLCXD2 | DEDD2 | 0.659094 | 4 | 0 | 4 |
| PLCXD2 | ADSL | 0.6549 | 3 | 0 | 3 |
| PLCXD2 | DHX35 | 0.646967 | 3 | 0 | 3 |
| PLCXD2 | GGN | 0.640134 | 3 | 0 | 3 |
| PLCXD2 | SP4 | 0.634125 | 3 | 0 | 3 |
| PLCXD2 | USP42 | 0.626924 | 3 | 0 | 3 |
| PLCXD2 | PRPSAP2 | 0.621081 | 3 | 0 | 3 |
| PLCXD2 | DDX19A | 0.620157 | 3 | 0 | 3 |
| PLCXD2 | TEX19 | 0.61302 | 3 | 0 | 3 |
| PLCXD2 | PTOV1 | 0.61028 | 3 | 0 | 3 |
| PLCXD2 | SUZ12 | 0.606713 | 4 | 0 | 3 |
| PLCXD2 | CNTD1 | 0.604246 | 4 | 0 | 3 |
| PLCXD2 | THOC5 | 0.575411 | 4 | 0 | 3 |
| PLCXD2 | EPOR | 0.574179 | 3 | 0 | 3 |
| PLCXD2 | TCEANC2 | 0.570317 | 3 | 0 | 3 |
| PLCXD2 | DHDH | 0.563498 | 5 | 0 | 4 |
For details and further investigation, click here
