| Full name: WW domain binding protein 2 | Alias Symbol: WBP-2|GRAMD6 | ||
| Type: protein-coding gene | Cytoband: 17q25.1 | ||
| Entrez ID: 23558 | HGNC ID: HGNC:12738 | Ensembl Gene: ENSG00000132471 | OMIM ID: 606962 |
| Drug and gene relationship at DGIdb | |||
Expression of WBP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WBP2 | 23558 | 209117_at | -0.0402 | 0.9399 | |
| GSE20347 | WBP2 | 23558 | 209117_at | -0.5487 | 0.0002 | |
| GSE23400 | WBP2 | 23558 | 209117_at | -0.3190 | 0.0000 | |
| GSE26886 | WBP2 | 23558 | 209117_at | -1.5898 | 0.0000 | |
| GSE29001 | WBP2 | 23558 | 209117_at | -0.3959 | 0.1127 | |
| GSE38129 | WBP2 | 23558 | 209117_at | -0.5934 | 0.0000 | |
| GSE45670 | WBP2 | 23558 | 209117_at | 0.1351 | 0.4565 | |
| GSE53622 | WBP2 | 23558 | 137599 | -0.6084 | 0.0000 | |
| GSE53624 | WBP2 | 23558 | 137599 | -0.2591 | 0.0000 | |
| GSE63941 | WBP2 | 23558 | 209117_at | 1.0360 | 0.0027 | |
| GSE77861 | WBP2 | 23558 | 209117_at | -0.2349 | 0.4460 | |
| GSE97050 | WBP2 | 23558 | A_23_P15299 | -0.1131 | 0.5742 | |
| SRP007169 | WBP2 | 23558 | RNAseq | -1.4052 | 0.0000 | |
| SRP008496 | WBP2 | 23558 | RNAseq | -1.4827 | 0.0000 | |
| SRP064894 | WBP2 | 23558 | RNAseq | -0.1502 | 0.4734 | |
| SRP133303 | WBP2 | 23558 | RNAseq | -0.1320 | 0.3848 | |
| SRP159526 | WBP2 | 23558 | RNAseq | -0.4968 | 0.0019 | |
| SRP193095 | WBP2 | 23558 | RNAseq | -0.2492 | 0.1690 | |
| SRP219564 | WBP2 | 23558 | RNAseq | -0.5101 | 0.1219 | |
| TCGA | WBP2 | 23558 | RNAseq | -0.1346 | 0.0020 |
Upregulated datasets: 1; Downregulated datasets: 3.
Survival by WBP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WBP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WBP2 | 23558 | 7 | 2 | 21 | |
| GSE20123 | WBP2 | 23558 | 7 | 2 | 21 | |
| GSE43470 | WBP2 | 23558 | 5 | 3 | 35 | |
| GSE46452 | WBP2 | 23558 | 34 | 0 | 25 | |
| GSE47630 | WBP2 | 23558 | 8 | 1 | 31 | |
| GSE54993 | WBP2 | 23558 | 2 | 5 | 63 | |
| GSE54994 | WBP2 | 23558 | 10 | 4 | 39 | |
| GSE60625 | WBP2 | 23558 | 6 | 0 | 5 | |
| GSE74703 | WBP2 | 23558 | 5 | 1 | 30 | |
| GSE74704 | WBP2 | 23558 | 5 | 1 | 14 | |
| TCGA | WBP2 | 23558 | 32 | 9 | 55 |
Total number of gains: 121; Total number of losses: 28; Total Number of normals: 339.
Somatic mutations of WBP2:
Generating mutation plots.
Highly correlated genes for WBP2:
Showing top 20/810 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WBP2 | PRPF38A | 0.823791 | 3 | 0 | 3 |
| WBP2 | TRAPPC1 | 0.817718 | 3 | 0 | 3 |
| WBP2 | UNC5B | 0.790102 | 3 | 0 | 3 |
| WBP2 | STAU2 | 0.7758 | 3 | 0 | 3 |
| WBP2 | PTGES2 | 0.775442 | 3 | 0 | 3 |
| WBP2 | CCNDBP1 | 0.773711 | 3 | 0 | 3 |
| WBP2 | MEAF6 | 0.77008 | 3 | 0 | 3 |
| WBP2 | ABHD14B | 0.763156 | 5 | 0 | 5 |
| WBP2 | FBXO8 | 0.757396 | 3 | 0 | 3 |
| WBP2 | UGP2 | 0.745866 | 4 | 0 | 4 |
| WBP2 | MORC3 | 0.743227 | 3 | 0 | 3 |
| WBP2 | SETD4 | 0.741337 | 3 | 0 | 3 |
| WBP2 | EXOC3L1 | 0.740011 | 3 | 0 | 3 |
| WBP2 | AP3M1 | 0.739629 | 3 | 0 | 3 |
| WBP2 | CD2AP | 0.730818 | 3 | 0 | 3 |
| WBP2 | VPS25 | 0.727899 | 3 | 0 | 3 |
| WBP2 | MBOAT2 | 0.723115 | 4 | 0 | 4 |
| WBP2 | C16orf70 | 0.722496 | 3 | 0 | 3 |
| WBP2 | RBM20 | 0.719417 | 3 | 0 | 3 |
| WBP2 | SLC35A4 | 0.713606 | 6 | 0 | 5 |
For details and further investigation, click here
