| Full name: meiotic double-stranded break formation protein 1 | Alias Symbol: MGC40042|SPATA38 | ||
| Type: protein-coding gene | Cytoband: 22q13.2 | ||
| Entrez ID: 150365 | HGNC ID: HGNC:28613 | Ensembl Gene: ENSG00000167077 | OMIM ID: 608797 |
| Drug and gene relationship at DGIdb | |||
Expression of MEI1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MEI1 | 150365 | 1554208_at | 0.0123 | 0.9891 | |
| GSE26886 | MEI1 | 150365 | 230011_at | -0.2095 | 0.1171 | |
| GSE45670 | MEI1 | 150365 | 230011_at | -0.0850 | 0.5423 | |
| GSE53622 | MEI1 | 150365 | 16097 | 0.1454 | 0.3116 | |
| GSE53624 | MEI1 | 150365 | 16097 | -0.0129 | 0.9415 | |
| GSE63941 | MEI1 | 150365 | 1554208_at | 0.3044 | 0.0546 | |
| GSE77861 | MEI1 | 150365 | 1554208_at | 0.1020 | 0.3712 | |
| GSE97050 | MEI1 | 150365 | A_23_P211561 | 0.6334 | 0.1791 | |
| SRP064894 | MEI1 | 150365 | RNAseq | 0.5411 | 0.1457 | |
| SRP133303 | MEI1 | 150365 | RNAseq | -0.1541 | 0.6711 | |
| SRP159526 | MEI1 | 150365 | RNAseq | 0.2668 | 0.7649 | |
| SRP219564 | MEI1 | 150365 | RNAseq | 1.1041 | 0.0729 | |
| TCGA | MEI1 | 150365 | RNAseq | -0.6336 | 0.0349 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MEI1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MEI1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MEI1 | 150365 | 6 | 5 | 19 | |
| GSE20123 | MEI1 | 150365 | 6 | 4 | 20 | |
| GSE43470 | MEI1 | 150365 | 5 | 6 | 32 | |
| GSE46452 | MEI1 | 150365 | 31 | 2 | 26 | |
| GSE47630 | MEI1 | 150365 | 9 | 4 | 27 | |
| GSE54993 | MEI1 | 150365 | 3 | 6 | 61 | |
| GSE54994 | MEI1 | 150365 | 11 | 8 | 34 | |
| GSE60625 | MEI1 | 150365 | 5 | 0 | 6 | |
| GSE74703 | MEI1 | 150365 | 5 | 4 | 27 | |
| GSE74704 | MEI1 | 150365 | 3 | 2 | 15 | |
| TCGA | MEI1 | 150365 | 27 | 14 | 55 |
Total number of gains: 111; Total number of losses: 55; Total Number of normals: 322.
Somatic mutations of MEI1:
Generating mutation plots.
Highly correlated genes for MEI1:
Showing top 20/135 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MEI1 | MZB1 | 0.829654 | 5 | 0 | 5 |
| MEI1 | CNGB3 | 0.755602 | 3 | 0 | 3 |
| MEI1 | PNOC | 0.75213 | 3 | 0 | 3 |
| MEI1 | E2F1 | 0.746893 | 3 | 0 | 3 |
| MEI1 | MFNG | 0.740353 | 4 | 0 | 4 |
| MEI1 | TBXAS1 | 0.734647 | 4 | 0 | 4 |
| MEI1 | CHTF8 | 0.732015 | 4 | 0 | 4 |
| MEI1 | CD48 | 0.731995 | 6 | 0 | 6 |
| MEI1 | CD27 | 0.717199 | 3 | 0 | 3 |
| MEI1 | ATP2B3 | 0.71667 | 3 | 0 | 3 |
| MEI1 | HTRA4 | 0.711207 | 3 | 0 | 3 |
| MEI1 | IRF4 | 0.697129 | 5 | 0 | 4 |
| MEI1 | CYTIP | 0.690967 | 4 | 0 | 4 |
| MEI1 | CD52 | 0.689972 | 6 | 0 | 6 |
| MEI1 | SNORA71A | 0.682581 | 3 | 0 | 3 |
| MEI1 | TIMD4 | 0.680966 | 4 | 0 | 4 |
| MEI1 | FMNL1 | 0.679043 | 5 | 0 | 4 |
| MEI1 | VAV1 | 0.67613 | 3 | 0 | 3 |
| MEI1 | CDK2 | 0.672395 | 3 | 0 | 3 |
| MEI1 | P2RY10 | 0.672385 | 5 | 0 | 5 |
For details and further investigation, click here
