CPNE5

 

Full name: copine 5 Alias Symbol: CPN5|COPN5|KIAA1599
Type: protein-coding gene Cytoband: 6p21.2
Entrez ID: 57699 HGNC ID: HGNC:2318 Ensembl Gene: ENSG00000124772 OMIM ID: 604209
Drug and gene relationship at DGIdb

 

Expression of CPNE5:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CPNE5 57699 227189_at 0.0893 0.9323
GSE26886 CPNE5 57699 227189_at -0.3171 0.0805
GSE45670 CPNE5 57699 227189_at 0.0103 0.9445
GSE53622 CPNE5 57699 149805 0.2162 0.0028
GSE53624 CPNE5 57699 149805 0.0713 0.4217
GSE63941 CPNE5 57699 227189_at -0.2807 0.0270
GSE77861 CPNE5 57699 227189_at 0.0031 0.9816
GSE97050 CPNE5 57699 A_23_P360804 0.5393 0.1839
SRP064894 CPNE5 57699 RNAseq 1.2726 0.0001
SRP133303 CPNE5 57699 RNAseq 0.1665 0.5288
SRP159526 CPNE5 57699 RNAseq 0.0969 0.8706
SRP193095 CPNE5 57699 RNAseq 0.0054 0.9871
SRP219564 CPNE5 57699 RNAseq 1.3108 0.0009
TCGA CPNE5 57699 RNAseq -0.4523 0.0031

Upregulated datasets: 2; Downregulated datasets: 0.  


 

Survival by CPNE5 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of CPNE5:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CPNE5 57699 6 0 24
GSE20123 CPNE5 57699 6 0 24
GSE43470 CPNE5 57699 5 1 37
GSE46452 CPNE5 57699 2 9 48
GSE47630 CPNE5 57699 8 4 28
GSE54993 CPNE5 57699 3 1 66
GSE54994 CPNE5 57699 10 5 38
GSE60625 CPNE5 57699 1 0 10
GSE74703 CPNE5 57699 5 0 31
GSE74704 CPNE5 57699 3 0 17
TCGA CPNE5 57699 15 15 66

Total number of gains: 64; Total number of losses: 35; Total Number of normals: 389.  


 

Somatic mutations of CPNE5:

 

Generating mutation plots.

 

Highly correlated genes for CPNE5:

 

Showing top 20/69 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CPNE5PNOC0.765884404
CPNE5ZC3H12D0.722914303
CPNE5ERCC10.682205303
CPNE5CD79A0.677755605
CPNE5IRF40.676868504
CPNE5FCRL50.660414706
CPNE5CLECL10.66504
CPNE5DERL30.659968303
CPNE5STAP10.654059404
CPNE5MAP4K10.650316505
CPNE5IL21R0.642397504
CPNE5TCL1A0.641599404
CPNE5RHOH0.637643303
CPNE5IL2RB0.636124303
CPNE5PAX50.632504503
CPNE5MPDU10.632463303
CPNE5NT5DC40.624346303
CPNE5CD480.623475403
CPNE5CCL240.618344403
CPNE5IGLL10.616636503

For details and further investigation, click here