| Full name: stromal antigen 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 7q22.1 | ||
| Entrez ID: 10734 | HGNC ID: HGNC:11356 | Ensembl Gene: ENSG00000066923 | OMIM ID: 608489 |
| Drug and gene relationship at DGIdb | |||
Expression of STAG3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STAG3 | 10734 | 219753_at | 0.0729 | 0.8925 | |
| GSE20347 | STAG3 | 10734 | 219753_at | -0.0220 | 0.7561 | |
| GSE23400 | STAG3 | 10734 | 219753_at | -0.0852 | 0.0192 | |
| GSE26886 | STAG3 | 10734 | 219753_at | 0.0838 | 0.4708 | |
| GSE29001 | STAG3 | 10734 | 219753_at | 0.1570 | 0.5500 | |
| GSE38129 | STAG3 | 10734 | 219753_at | -0.0557 | 0.5647 | |
| GSE45670 | STAG3 | 10734 | 219753_at | 0.0766 | 0.6498 | |
| GSE53622 | STAG3 | 10734 | 146005 | 0.7246 | 0.0000 | |
| GSE53624 | STAG3 | 10734 | 34176 | 0.2336 | 0.0010 | |
| GSE63941 | STAG3 | 10734 | 219753_at | 0.3597 | 0.0291 | |
| GSE77861 | STAG3 | 10734 | 219753_at | -0.0651 | 0.5092 | |
| GSE97050 | STAG3 | 10734 | A_32_P170749 | 0.1545 | 0.4504 | |
| SRP133303 | STAG3 | 10734 | RNAseq | 0.2712 | 0.0934 | |
| SRP159526 | STAG3 | 10734 | RNAseq | 0.2735 | 0.6207 | |
| SRP193095 | STAG3 | 10734 | RNAseq | 0.9811 | 0.0001 | |
| SRP219564 | STAG3 | 10734 | RNAseq | 0.8910 | 0.0250 | |
| TCGA | STAG3 | 10734 | RNAseq | 0.2430 | 0.4179 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by STAG3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STAG3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STAG3 | 10734 | 13 | 0 | 17 | |
| GSE20123 | STAG3 | 10734 | 13 | 0 | 17 | |
| GSE43470 | STAG3 | 10734 | 6 | 2 | 35 | |
| GSE46452 | STAG3 | 10734 | 11 | 1 | 47 | |
| GSE47630 | STAG3 | 10734 | 7 | 3 | 30 | |
| GSE54993 | STAG3 | 10734 | 1 | 9 | 60 | |
| GSE54994 | STAG3 | 10734 | 16 | 3 | 34 | |
| GSE60625 | STAG3 | 10734 | 0 | 0 | 11 | |
| GSE74703 | STAG3 | 10734 | 6 | 1 | 29 | |
| GSE74704 | STAG3 | 10734 | 9 | 0 | 11 | |
| TCGA | STAG3 | 10734 | 52 | 6 | 38 |
Total number of gains: 134; Total number of losses: 25; Total Number of normals: 329.
Somatic mutations of STAG3:
Generating mutation plots.
Highly correlated genes for STAG3:
Showing top 20/126 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STAG3 | VTCN1 | 0.729451 | 3 | 0 | 3 |
| STAG3 | SLAMF6 | 0.692784 | 3 | 0 | 3 |
| STAG3 | PNOC | 0.678138 | 5 | 0 | 4 |
| STAG3 | MS4A1 | 0.652657 | 4 | 0 | 3 |
| STAG3 | ADAM32 | 0.641898 | 3 | 0 | 3 |
| STAG3 | RFC4 | 0.624589 | 3 | 0 | 3 |
| STAG3 | XKR8 | 0.619903 | 3 | 0 | 3 |
| STAG3 | FCRL3 | 0.618729 | 4 | 0 | 3 |
| STAG3 | ST6GAL1 | 0.61699 | 4 | 0 | 3 |
| STAG3 | C15orf39 | 0.613714 | 3 | 0 | 3 |
| STAG3 | GTSF1L | 0.613246 | 4 | 0 | 3 |
| STAG3 | CST1 | 0.607311 | 3 | 0 | 3 |
| STAG3 | SYNGR2 | 0.599103 | 4 | 0 | 3 |
| STAG3 | SIT1 | 0.598842 | 6 | 0 | 4 |
| STAG3 | PTGES2 | 0.598101 | 3 | 0 | 3 |
| STAG3 | DTX1 | 0.597517 | 5 | 0 | 3 |
| STAG3 | ACAP1 | 0.594791 | 3 | 0 | 3 |
| STAG3 | RAB15 | 0.594719 | 4 | 0 | 3 |
| STAG3 | SASH3 | 0.593778 | 4 | 0 | 3 |
| STAG3 | BTBD6 | 0.59036 | 3 | 0 | 3 |
For details and further investigation, click here
