RPA3

 

Full name: replication protein A3 Alias Symbol: REPA3
Type: protein-coding gene Cytoband: 7p21.3
Entrez ID: 6119 HGNC ID: HGNC:10291 Ensembl Gene: ENSG00000106399 OMIM ID: 179837
Drug and gene relationship at DGIdb

 

Expression of RPA3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RPA3 6119 209507_at 0.4278 0.4421
GSE20347 RPA3 6119 209507_at 0.9667 0.0004
GSE23400 RPA3 6119 209507_at 0.8450 0.0000
GSE26886 RPA3 6119 209507_at 1.2965 0.0000
GSE29001 RPA3 6119 209507_at 0.6850 0.1523
GSE38129 RPA3 6119 209507_at 1.1249 0.0000
GSE45670 RPA3 6119 209507_at 0.7790 0.0001
GSE53622 RPA3 6119 91539 0.8303 0.0000
GSE53624 RPA3 6119 91539 1.1083 0.0000
GSE63941 RPA3 6119 209507_at 2.6050 0.0001
GSE77861 RPA3 6119 209507_at 0.5825 0.0026
GSE97050 RPA3 6119 A_23_P256455 0.5303 0.3997
SRP007169 RPA3 6119 RNAseq 1.1691 0.0231
SRP008496 RPA3 6119 RNAseq 1.4176 0.0001
SRP064894 RPA3 6119 RNAseq 1.0308 0.0004
SRP133303 RPA3 6119 RNAseq 1.0993 0.0000
SRP159526 RPA3 6119 RNAseq 0.4095 0.0958
SRP193095 RPA3 6119 RNAseq 0.2400 0.1935
SRP219564 RPA3 6119 RNAseq 0.4153 0.3165
TCGA RPA3 6119 RNAseq 0.4602 0.0000

Upregulated datasets: 8; Downregulated datasets: 0.  

 

Survival by RPA3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of RPA3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RPA3 6119 15 2 13
GSE20123 RPA3 6119 15 2 13
GSE43470 RPA3 6119 8 0 35
GSE46452 RPA3 6119 11 1 47
GSE47630 RPA3 6119 9 1 30
GSE54993 RPA3 6119 0 6 64
GSE54994 RPA3 6119 21 1 31
GSE60625 RPA3 6119 0 0 11
GSE74703 RPA3 6119 8 0 28
GSE74704 RPA3 6119 9 2 9
TCGA RPA3 6119 56 4 36

Total number of gains: 152; Total number of losses: 19; Total Number of normals: 317.  

 

Somatic mutations of RPA3:

 

Generating mutation plots.

 

Highly correlated genes for RPA3:

 

Showing top 20/1884 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RPA3LSM50.79646513013
RPA3HES40.781842303
RPA3MMS22L0.773095303
RPA3PCNA0.77234813013
RPA3FBXO160.767661303
RPA3WDR540.766552808
RPA3CCNB20.76442712012
RPA3AIMP20.76390411011
RPA3TRAF70.762731606
RPA3NUDT10.76114113013
RPA3MRPS230.759923808
RPA3GINS10.75221412012
RPA3DCAF130.75202505
RPA3MCM60.75201913013
RPA3MRPL470.751199707
RPA3CKS1B0.75106613012
RPA3RFC20.75058312012
RPA3POLR2G0.74788911011
RPA3MRGBP0.746155909
RPA3DTYMK0.74589612011

For details and further investigation, click here